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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [6]
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- Product number
- ABIN362737 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Forkhead Box O1 (FOXO1) (AA 254-258) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around AA 254-258 (A-A-S-M-D) derived from Human FKHR, FOXO1A. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- AA 254-258
- Isotype
- IgG
- Vial size
- 50 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references Atrial natriuretic peptide suppresses Th17 development through regulation of cGMP-dependent protein kinase and PI3K-Akt signaling pathways.
Nuclear/cytoplasmic shuttling of the transcription factor FoxO1 is regulated by neurotrophic factors.
Protein kinase CK2 phosphorylates and upregulates Akt/PKB.
Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity.
Restoration of SHIP activity in a human leukemia cell line downregulates constitutively activated phosphatidylinositol 3-kinase/Akt/GSK-3beta signaling and leads to an increased transit time through the G1 phase of the cell cycle.
Multiple elements regulate nuclear/cytoplasmic shuttling of FOXO1: characterization of phosphorylation- and 14-3-3-dependent and -independent mechanisms.
Ma L, Li J, Wang G, Gong S, Zhang L, Li K, Ji X, Liu Y, Chen P, Xiang X
Regulatory peptides 2013 Feb 10;181:9-16
Regulatory peptides 2013 Feb 10;181:9-16
Nuclear/cytoplasmic shuttling of the transcription factor FoxO1 is regulated by neurotrophic factors.
Gan L, Zheng W, Chabot JG, Unterman TG, Quirion R
Journal of neurochemistry 2005 Jun;93(5):1209-19
Journal of neurochemistry 2005 Jun;93(5):1209-19
Protein kinase CK2 phosphorylates and upregulates Akt/PKB.
Di Maira G, Salvi M, Arrigoni G, Marin O, Sarno S, Brustolon F, Pinna LA, Ruzzene M
Cell death and differentiation 2005 Jun;12(6):668-77
Cell death and differentiation 2005 Jun;12(6):668-77
Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity.
Smith WW, Norton DD, Gorospe M, Jiang H, Nemoto S, Holbrook NJ, Finkel T, Kusiak JW
The Journal of cell biology 2005 Apr 25;169(2):331-9
The Journal of cell biology 2005 Apr 25;169(2):331-9
Restoration of SHIP activity in a human leukemia cell line downregulates constitutively activated phosphatidylinositol 3-kinase/Akt/GSK-3beta signaling and leads to an increased transit time through the G1 phase of the cell cycle.
Horn S, Endl E, Fehse B, Weck MM, Mayr GW, Jücker M
Leukemia 2004 Nov;18(11):1839-49
Leukemia 2004 Nov;18(11):1839-49
Multiple elements regulate nuclear/cytoplasmic shuttling of FOXO1: characterization of phosphorylation- and 14-3-3-dependent and -independent mechanisms.
Zhao X, Gan L, Pan H, Kan D, Majeski M, Adam SA, Unterman TG
The Biochemical journal 2004 Mar 15;378(Pt 3):839-49
The Biochemical journal 2004 Mar 15;378(Pt 3):839-49
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