Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations [0]
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- Product number
- ABIN966149 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Forkhead Box O1 (FOXO1) antibody
- Antibody type
- Polyclonal
- Antigen
- The antiserum was produced against synthesized non-phosphopeptide derived from human FKHR around the phosphorylation site of serine 319.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Vial size
- 100 μg
- Concentration
- 100ug/100ul.
- Storage
- -20°C
Submitted references Multiple elements regulate nuclear/cytoplasmic shuttling of FOXO1: characterization of phosphorylation- and 14-3-3-dependent and -independent mechanisms.
Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion.
Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting.
Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence.
Zhao X, Gan L, Pan H, Kan D, Majeski M, Adam SA, Unterman TG
The Biochemical journal 2004 Mar 15;378(Pt 3):839-49
The Biochemical journal 2004 Mar 15;378(Pt 3):839-49
Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion.
Rena G, Woods YL, Prescott AR, Peggie M, Unterman TG, Williams MR, Cohen P
The EMBO journal 2002 May 1;21(9):2263-71
The EMBO journal 2002 May 1;21(9):2263-71
Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting.
Rena G, Prescott AR, Guo S, Cohen P, Unterman TG
The Biochemical journal 2001 Mar 15;354(Pt 3):605-12
The Biochemical journal 2001 Mar 15;354(Pt 3):605-12
Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence.
Guo S, Rena G, Cichy S, He X, Cohen P, Unterman T
The Journal of biological chemistry 1999 Jun 11;274(24):17184-92
The Journal of biological chemistry 1999 Jun 11;274(24):17184-92
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