Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- 11493-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11493-1-AP, RRID:AB_2237967
- Product name
- PTPMT1 antibody
- Antibody type
- Polyclonal
- Description
- PTPMT1 antibody (Cat. #11493-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Phosphorylated SHMT2 Regulates Oncogenesis Through m(6)A Modification in Lung Adenocarcinoma.
PTPMT1 protects cardiomyocytes from necroptosis induced by γ-ray irradiation through alleviating mitochondria injury.
4EBP1 senses extracellular glucose deprivation and initiates cell death signaling in lung cancer.
Genome-wide CRISPR-Cas9 knockout library screening identified PTPMT1 in cardiolipin synthesis is crucial to survival in hypoxia in liver cancer.
A critical role of mitochondrial phosphatase Ptpmt1 in embryogenesis reveals a mitochondrial metabolic stress-induced differentiation checkpoint in embryonic stem cells.
Han T, Wang Y, Cheng M, Hu Q, Wan X, Huang M, Liu Y, Xun W, Xu J, Wang L, Luo R, Yuan Y, Wang K, Wang J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(18):e2307834
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(18):e2307834
PTPMT1 protects cardiomyocytes from necroptosis induced by γ-ray irradiation through alleviating mitochondria injury.
Yi J, Yue L, Zhang Y, Tao N, Duan H, Lv L, Tan Y, Wang H
American journal of physiology. Cell physiology 2023 Jun 1;324(6):C1320-C1331
American journal of physiology. Cell physiology 2023 Jun 1;324(6):C1320-C1331
4EBP1 senses extracellular glucose deprivation and initiates cell death signaling in lung cancer.
Wang Y, Lei J, Zhang S, Wang X, Jin J, Liu Y, Gan M, Yuan Y, Sun L, Li X, Han T, Wang JB
Cell death & disease 2022 Dec 27;13(12):1075
Cell death & disease 2022 Dec 27;13(12):1075
Genome-wide CRISPR-Cas9 knockout library screening identified PTPMT1 in cardiolipin synthesis is crucial to survival in hypoxia in liver cancer.
Bao MH, Yang C, Tse AP, Wei L, Lee D, Zhang MS, Goh CC, Chiu DK, Yuen VW, Law CT, Chin WC, Chui NN, Wong BP, Chan CY, Ng IO, Chung CY, Wong CM, Wong CC
Cell reports 2021 Jan 26;34(4):108676
Cell reports 2021 Jan 26;34(4):108676
A critical role of mitochondrial phosphatase Ptpmt1 in embryogenesis reveals a mitochondrial metabolic stress-induced differentiation checkpoint in embryonic stem cells.
Shen J, Liu X, Yu WM, Liu J, Nibbelink MG, Guo C, Finkel T, Qu CK
Molecular and cellular biology 2011 Dec;31(24):4902-16
Molecular and cellular biology 2011 Dec;31(24):4902-16
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse pancreas tissue were subjected to SDS PAGE followed by western blot with 11493-1-AP(PTPMT1 antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PTPMT1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PTPMT1. This antibody recognizes human, mouse, rat antigen. The PTPMT1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.