Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Western blot [2]
- Other assay [1]
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Validation data
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- Product number
- PA5-80956 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- PTPMT1 Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full-length protein
- Description
- This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human PTPMT1.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µL
- Concentration
- 1 mg/mL
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Submitted references PAX2 promotes epithelial ovarian cancer progression involving fatty acid metabolic reprogramming.
Feng Y, Tang Y, Mao Y, Liu Y, Yao D, Yang L, Garson K, Vanderhyden BC, Wang Q
International journal of oncology 2020 Mar;56(3):697-708
International journal of oncology 2020 Mar;56(3):697-708
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot analysis of PTPMT1 in Lane A: 293T Whole Cell Lysate (60 µg). Samples were probed using a PTPMT1 Polyclonal Antibody (Product # PA5-80956) at a 1:500 dilution, followed by a Goat Anti-Rabbit IgG (H+L), Dylight 800 Secondary Antibody at a 1:10000 dilution. Western blot was performed under reducing conditions. Predicted band size:23 kDa. Observed band size:18 kDa.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western Blot using PTPMT1 Polyclonal Antibody (Product # PA5-80956) at 1:500 dilution. Lane A: 293T Whole Cell Lysate. Lysates/proteins at 60 μg per lane. Secondary Goat Anti-Rabbit IgG H&L (DyLight™ 800) at 1:10,000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size: 23 kDa. Observed band size: 18 kDa.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Figure 5 ACAA2 overexpression is associated with a poor prognosis of patients with ovarian cancer. (A and B) Kaplan-Meier progression-free survival curves for patients with a low or high expression of (A) ACAA2 or (B) PNLIP among the total number of patients; (C-E) Kaplan-Meier progression-free survival curves for patients with (C) a negative PAX2 expression (PAX2 - ) or positive PAX2 expression (PAX2 + ), (D) low or high ACAA2 expression or (E) low or high PNLIP in expression RAS positive (RAS + ) subgroup.