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Learn19949-1-AP
antibody from Proteintech Group
Targeting: GLI3
ACLS, GCPS, PAP-A, PAPA, PAPA1, PAPB, PHS, PPDIV
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- 19949-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#19949-1-AP, RRID:AB_11182281
- Product name
- GLI3-Specific antibody
- Antibody type
- Polyclonal
- Description
- GLI3-Specific antibody (Cat. #19949-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references 1-Indanone retards cyst development in ADPKD mouse model by stabilizing tubulin and down-regulating anterograde transport of cilia.
Rosmarinic Acid Decreases the Malignancy of Pancreatic Cancer Through Inhibiting Gli1 Signaling.
Mutations in OSBPL2 cause hearing loss associated with primary cilia defects via sonic hedgehog signaling.
MicroRNA-223 restricts liver fibrosis by inhibiting the TAZ-IHH-GLI2 and PDGF signaling pathways via the crosstalk of multiple liver cell types.
Depletion of Ric-8B leads to reduced mTORC2 activity.
Combined inhibition of sonic Hedgehog signaling and histone deacetylase is an effective treatment for liver cancer.
Regulation of Survivin Isoform Expression by GLI Proteins in Ovarian Cancer.
Effects of baicalein on pancreatic cancer stem cells via modulation of sonic Hedgehog pathway.
Non-canonical Hedgehog signaling activation in ovarian borderline tumors and ovarian carcinomas.
mTORC1 regulates PTHrP to coordinate chondrocyte growth, proliferation and differentiation.
LKB1 Regulates Cerebellar Development by Controlling Sonic Hedgehog-mediated Granule Cell Precursor Proliferation and Granule Cell Migration.
GSK3β and Gli3 play a role in activation of Hedgehog-Gli pathway in human colon cancer - Targeting GSK3β downregulates the signaling pathway and reduces cell proliferation.
Li XW, Ran JH, Zhou H, He JZ, Qiu ZW, Wang SY, Wu MN, Zhu S, An YP, Ma A, Li M, Quan YZ, Li NN, Ren CQ, Yang BX
Acta pharmacologica Sinica 2023 Feb;44(2):406-420
Acta pharmacologica Sinica 2023 Feb;44(2):406-420
Rosmarinic Acid Decreases the Malignancy of Pancreatic Cancer Through Inhibiting Gli1 Signaling.
Zhou X, Wang W, Li Z, Chen L, Wen C, Ruan Q, Xu Z, Liu R, Xu J, Bai Y, Deng J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153861
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153861
Mutations in OSBPL2 cause hearing loss associated with primary cilia defects via sonic hedgehog signaling.
Shi H, Wang H, Zhang C, Lu Y, Yao J, Chen Z, Xing G, Wei Q, Cao X
JCI insight 2022 Feb 22;7(4)
JCI insight 2022 Feb 22;7(4)
MicroRNA-223 restricts liver fibrosis by inhibiting the TAZ-IHH-GLI2 and PDGF signaling pathways via the crosstalk of multiple liver cell types.
Wang X, Seo W, Park SH, Fu Y, Hwang S, Rodrigues RM, Feng D, Gao B, He Y
International journal of biological sciences 2021;17(4):1153-1167
International journal of biological sciences 2021;17(4):1153-1167
Depletion of Ric-8B leads to reduced mTORC2 activity.
Nagai MH, Xavier VPS, Gutiyama LM, Machado CF, Reis AH, Donnard ER, Galante PAF, Abreu JG, Festuccia WT, Malnic B
PLoS genetics 2020 May;16(5):e1008255
PLoS genetics 2020 May;16(5):e1008255
Combined inhibition of sonic Hedgehog signaling and histone deacetylase is an effective treatment for liver cancer.
Li J, Cai H, Li H, Liu Y, Wang Y, Shi Y, Sun Y, Song H, Wang D
Oncology reports 2019 Mar;41(3):1991-1997
Oncology reports 2019 Mar;41(3):1991-1997
Regulation of Survivin Isoform Expression by GLI Proteins in Ovarian Cancer.
Trnski D, Gregorić M, Levanat S, Ozretić P, Rinčić N, Vidaković TM, Kalafatić D, Maurac I, Orešković S, Sabol M, Musani V
Cells 2019 Feb 6;8(2)
Cells 2019 Feb 6;8(2)
Effects of baicalein on pancreatic cancer stem cells via modulation of sonic Hedgehog pathway.
Song L, Chen X, Wang P, Gao S, Qu C, Liu L
Acta biochimica et biophysica Sinica 2018 Jun 1;50(6):586-596
Acta biochimica et biophysica Sinica 2018 Jun 1;50(6):586-596
Non-canonical Hedgehog signaling activation in ovarian borderline tumors and ovarian carcinomas.
Ozretić P, Trnski D, Musani V, Maurac I, Kalafatić D, Orešković S, Levanat S, Sabol M
International journal of oncology 2017 Dec;51(6):1869-1877
International journal of oncology 2017 Dec;51(6):1869-1877
mTORC1 regulates PTHrP to coordinate chondrocyte growth, proliferation and differentiation.
Yan B, Zhang Z, Jin D, Cai C, Jia C, Liu W, Wang T, Li S, Zhang H, Huang B, Lai P, Wang H, Liu A, Zeng C, Cai D, Jiang Y, Bai X
Nature communications 2016 Apr 4;7:11151
Nature communications 2016 Apr 4;7:11151
LKB1 Regulates Cerebellar Development by Controlling Sonic Hedgehog-mediated Granule Cell Precursor Proliferation and Granule Cell Migration.
Men Y, Zhang A, Li H, Jin Y, Sun X, Li H, Gao J
Scientific reports 2015 Nov 9;5:16232
Scientific reports 2015 Nov 9;5:16232
GSK3β and Gli3 play a role in activation of Hedgehog-Gli pathway in human colon cancer - Targeting GSK3β downregulates the signaling pathway and reduces cell proliferation.
Trnski D, Sabol M, Gojević A, Martinić M, Ozretić P, Musani V, Ramić S, Levanat S
Biochimica et biophysica acta 2015 Dec;1852(12):2574-84
Biochimica et biophysica acta 2015 Dec;1852(12):2574-84
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human placenta tissue were subjected to SDS PAGE followed by western blot with 19949-1-AP(GLI3-Specific antibody) at dilution of 1:400
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GLI3-Specific antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human GLI3-Specific. This antibody recognizes human,mouse,rat antigen. The GLI3-Specific antibody has been validated for the following applications: ELISA, WB, IF, IHC analysis.
