17516-1-AP

antibody from Proteintech Group

Targeting: KRT17 PCHC1

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Flow cytometry (Supportive data in Antibodypedia)

Antibody Data

Product number

17516-1-AP

Provider

Proteintech Group

Proper citation

Proteintech Cat#17516-1-AP, RRID:AB_2133036

Product name

Cytokeratin 17-Specific antibody

Antibody type

Polyclonal

Description

KD/KO validated Cytokeratin 17-Specific antibody (Cat. #17516-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Low Expression of Keratin17 is Related to Poor Prognosis in Bladder Cancer.

Wu J, Xu H, Ji H, Zhai B, Zhu J, Gao M, Zhu H, Wang X
OncoTargets and therapy 2021;14:577-587

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The keratin 17/YAP/IL6 axis contributes to E-cadherin loss and aggressiveness of diffuse gastric cancer.

Li M, Rao X, Cui Y, Zhang L, Li X, Wang B, Zheng Y, Teng L, Zhou T, Zhuo W
Oncogene 2021 Nov 29;

---

[Sitagliptin inhibits lipopolysaccharide-induced inflammatory response in human gingival fibroblasts by blocking nuclear factor-κB signaling pathway].

Liu X, Kang WY, Shang LL, Ge SH
Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology 2021 Apr 1;39(2):153-163

---

A Preclinical Trial and Molecularly Annotated Patient Cohort Identify Predictive Biomarkers in Homologous Recombination-deficient Pancreatic Cancer.

Wang Y, Park JYP, Pacis A, Denroche RE, Jang GH, Zhang A, Cuggia A, Domecq C, Monlong J, Raitses-Gurevich M, Grant RC, Borgida A, Holter S, Stossel C, Bu S, Masoomian M, Lungu IM, Bartlett JMS, Wilson JM, Gao ZH, Riazalhosseini Y, Asselah J, Bouganim N, Cabrera T, Boucher LM, Valenti D, Biagi J, Greenwood CMT, Polak P, Foulkes WD, Golan T, O'Kane GM, Fischer SE, Knox JJ, Gallinger S, Zogopoulos G
Clinical cancer research : an official journal of the American Association for Cancer Research 2020 Oct 15;26(20):5462-5476

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Anillin regulates breast cancer cell migration, growth, and metastasis by non-canonical mechanisms involving control of cell stemness and differentiation.

Wang D, Naydenov NG, Dozmorov MG, Koblinski JE, Ivanov AI
Breast cancer research : BCR 2020 Jan 7;22(1):3

---

The potential of Diosgenin in treating psoriasis: Studies from HaCaT keratinocytes and imiquimod-induced murine model.

Wu S, Zhao M, Sun Y, Xie M, Le K, Xu M, Huang C
Life sciences 2020 Jan 15;241:117115

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Overexpression of KRT17 promotes proliferation and invasion of non-small cell lung cancer and indicates poor prognosis.

Wang Z, Yang MQ, Lei L, Fei LR, Zheng YW, Huang WJ, Li ZH, Liu CC, Xu HT
Cancer management and research 2019;11:7485-7497

---

Spatiotemporal immune zonation of the human kidney.

Stewart BJ, Ferdinand JR, Young MD, Mitchell TJ, Loudon KW, Riding AM, Richoz N, Frazer GL, Staniforth JUL, Vieira Braga FA, Botting RA, Popescu DM, Vento-Tormo R, Stephenson E, Cagan A, Farndon SJ, Polanski K, Efremova M, Green K, Del Castillo Velasco-Herrera M, Guzzo C, Collord G, Mamanova L, Aho T, Armitage JN, Riddick ACP, Mushtaq I, Farrell S, Rampling D, Nicholson J, Filby A, Burge J, Lisgo S, Lindsay S, Bajenoff M, Warren AY, Stewart GD, Sebire N, Coleman N, Haniffa M, Teichmann SA, Behjati S, Clatworthy MR
Science (New York, N.Y.) 2019 Sep 27;365(6460):1461-1466

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Cytokeratin expression in epidermal stem cells in skin adnexal tumors.

Zhou X, Li G, Wang D, Sun X, Li X
Oncology letters 2019 Jan;17(1):927-932

---

Keratin17 Promotes Tumor Growth and is Associated with Poor Prognosis in Gastric Cancer.

Hu H, Xu DH, Huang XX, Zhu CC, Xu J, Zhang ZZ, Zhao G
Journal of Cancer 2018;9(2):346-357

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

A431 cells were subjected to SDS PAGE followed by western blot with 17516-1-AP(KRT17-Specific antibody) at dilution of 1:300

Sample type

cell line

Immunocytochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunofluorescent analysis of Hela cells, using KRT17 antibody 17516-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

Sample type

cell line

Immunohistochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human cervical cancer using 17516-1-AP(KRT17-Specific antibody) at dilution of 1:50 (under 10x lens)

Sample type

tissue

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human cervical cancer using 17516-1-AP(KRT17-Specific antibody) at dilution of 1:50 (under 40x lens)

Sample type

tissue

Flow cytometry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

The Cytokeratin 17-Specific antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human Cytokeratin 17-Specific. This antibody recognizes human,mouse,rat antigen. The Cytokeratin 17-Specific antibody has been validated for the following applications: ELISA, WB, IHC, IF, FC analysis.

Appendix

17516-1-AP.pdf

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