Antibody data
- Antibody Data
 - Antigen structure
 - References [3]
 - Comments [0]
 - Validations
 - Immunocytochemistry [1]
 
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Validation data
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- Product number
 - HPA055619 - Provider product page

 - Provider
 - Atlas Antibodies
 - Proper citation
 - Atlas Antibodies Cat#HPA055619, RRID:AB_2682864
 - Product name
 - Anti-DEPDC5
 - Antibody type
 - Polyclonal
 - Description
 - Polyclonal Antibody against Human DEPDC5, Gene description: DEP domain containing 5, Alternative Gene Names: DEP.5, KIAA0645, Validated applications: ICC, Uniprot ID: O75140, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
 - Reactivity
 - Human
 - Host
 - Rabbit
 - Conjugate
 - Unconjugated
 - Isotype
 - IgG
 - Vial size
 - 100 µl
 - Concentration
 - 0.3 mg/ml
 - Storage
 - Store at +4°C for short term storage. Long time storage is recommended at -20°C.
 - Handling
 - The antibody solution should be gently mixed before use.
 
Submitted references		NPRL2 downâregulation facilitates the growth of hepatocellular carcinoma via the mTOR pathway and autophagy suppression
				
DEPDC5-dependent mTORC1 signaling mechanisms are critical for the anti-seizure effects of acute fasting
				
DEPDC5 deficiency contributes to resistance to leucine starvation via p62 accumulation in hepatocellular carcinoma
				
		
	
			Wang Y, Tsai M, Chen Y, Hsieh P, Hung C, Lin H, Hsu Y, Yeh J, Hsiao P, Su Y, Ma C, Lee C, Lin C, Shu C, Li Y, Tsai M, Lin J, Peng W, Yu M, Lin C
Hepatology Communications 2022;6(12):3563-3577
		Hepatology Communications 2022;6(12):3563-3577
DEPDC5-dependent mTORC1 signaling mechanisms are critical for the anti-seizure effects of acute fasting
			Yuskaitis C, Modasia J, Schrötter S, Rossitto L, Groff K, Morici C, Mithal D, Chakrabarty R, Chandel N, Manning B, Sahin M
Cell Reports 2022;40(9):111278
		Cell Reports 2022;40(9):111278
DEPDC5 deficiency contributes to resistance to leucine starvation via p62 accumulation in hepatocellular carcinoma
			Mizuno Y, Shimada S, Akiyama Y, Watanabe S, Aida T, Ogawa K, Ono H, Mitsunori Y, Ban D, Kudo A, Arii S, Yamaoka S, Tanabe M, Tanaka S
Scientific Reports 2018;8(1)
		Scientific Reports 2018;8(1)
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					Supportive validation
					
									
				
		- Submitted by
 - Atlas Antibodies (provider)
 - Main image
 
- Experimental details
 - Immunofluorescent staining of human cell line HeLa shows localization to the Golgi apparatus.
 - Sample type
 - Human