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- Antibody Data
- Antigen structure
- References [27]
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- Product number
- 13721-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13721-1-AP, RRID:AB_2108296
- Product name
- Phospholemman/FXYD1 antibody
- Antibody type
- Polyclonal
- Description
- Phospholemman/FXYD1 antibody (Cat. #13721-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Effect of sample fractionation and normalization when immunoblotting for human muscle Na(+)/K(+)-ATPase subunits and glycogen synthase.
Skeletal muscle phenotype and game performance in elite women football players.
Effect of differentiation, de novo innervation, and electrical pulse stimulation on mRNA and protein expression of Na+,K+-ATPase, FXYD1, and FXYD5 in cultured human skeletal muscle cells.
No additive effect of acetaminophen when co-ingested with caffeine on cycling performance in well-trained young men.
Skeletal muscle proteins important for work capacity are altered with type 2 diabetes - Effect of 10-20-30 training.
Insulin-Like Growth Factor-1 Down-Regulates the Phosphorylation of FXYD1 and Rescues Behavioral Deficits in a Mouse Model of Rett Syndrome.
Fatigue-induced change in T-system excitability and its major cause in rat fast-twitch skeletal muscle in vivo.
Isoform-specific Na,K-ATPase and membrane cholesterol remodeling in motor endplates in distinct mouse models of myodystrophy.
Cycling with blood flow restriction improves performance and muscle K(+) regulation and alters the effect of anti-oxidant infusion in humans.
Axial Tubule Junctions Activate Atrial Ca(2+) Release Across Species.
The effect of repeated periods of speed endurance training on performance, running economy, and muscle adaptations.
Effect of tapering after a period of high-volume sprint interval training on running performance and muscular adaptations in moderately trained runners.
Cold-water immersion after training sessions: effects on fiber type-specific adaptations in muscle K(+) transport proteins to sprint-interval training in men.
Effect of increased and maintained frequency of speed endurance training on performance and muscle adaptations in runners.
Over-expression of microRNA-1 causes arrhythmia by disturbing intracellular trafficking system.
Effect of formoterol, a long-acting β2-adrenergic agonist, on muscle strength and power output, metabolism, and fatigue during maximal sprinting in men.
Distinct α2 Na,K-ATPase membrane pools are differently involved in early skeletal muscle remodeling during disuse.
Muscle variables of importance for physiological performance in competitive football.
Intensive training and reduced volume increases muscle FXYD1 expression and phosphorylation at rest and during exercise in athletes.
Mechanisms underlying enhancements in muscle force and power output during maximal cycle ergometer exercise induced by chronic β2-adrenergic stimulation in men.
Phospholemman is not required for the acute stimulation of Na⁺-K⁺-ATPase α₂-activity during skeletal muscle fatigue.
Concurrent speed endurance and resistance training improves performance, running economy, and muscle NHE1 in moderately trained runners.
Fibre type-specific change in FXYD1 phosphorylation during acute intense exercise in humans.
Chronic nicotine modifies skeletal muscle Na,K-ATPase activity through its interaction with the nicotinic acetylcholine receptor and phospholemman.
Influence of chronic and acute spinal cord injury on skeletal muscle Na+-K+-ATPase and phospholemman expression in humans.
Effect of exercise and training on phospholemman phosphorylation in human skeletal muscle.
The nicotinic acetylcholine receptor and the Na,K-ATPase alpha2 isoform interact to regulate membrane electrogenesis in skeletal muscle.
Thomassen M, Bangsbo J, Hostrup M
Analytical biochemistry 2023 Apr 1;666:115071
Analytical biochemistry 2023 Apr 1;666:115071
Skeletal muscle phenotype and game performance in elite women football players.
Mohr M, Fatouros IG, Jamurtas AZ, Draganidis D, Thomassen M, Ørntoft C, Ermidis G, Loules G, Batsilas D, Poulios A, Papanikolaou K, Randers MB, Krustrup P, Nybo L
Scandinavian journal of medicine & science in sports 2022 Apr;32 Suppl 1:39-53
Scandinavian journal of medicine & science in sports 2022 Apr;32 Suppl 1:39-53
Effect of differentiation, de novo innervation, and electrical pulse stimulation on mRNA and protein expression of Na+,K+-ATPase, FXYD1, and FXYD5 in cultured human skeletal muscle cells.
Jan V, Miš K, Nikolic N, Dolinar K, Petrič M, Bone A, Thoresen GH, Rustan AC, Marš T, Chibalin AV, Pirkmajer S
PloS one 2021;16(2):e0247377
PloS one 2021;16(2):e0247377
No additive effect of acetaminophen when co-ingested with caffeine on cycling performance in well-trained young men.
Jessen S, Eibye K, Christensen PM, Hostrup M, Bangsbo J
Journal of applied physiology (Bethesda, Md. : 1985) 2021 Jul 1;131(1):238-249
Journal of applied physiology (Bethesda, Md. : 1985) 2021 Jul 1;131(1):238-249
Skeletal muscle proteins important for work capacity are altered with type 2 diabetes - Effect of 10-20-30 training.
Baasch-Skytte T, Gunnarsson TP, Fiorenza M, Bangsbo J
Physiological reports 2021 Jan;9(1):e14681
Physiological reports 2021 Jan;9(1):e14681
Insulin-Like Growth Factor-1 Down-Regulates the Phosphorylation of FXYD1 and Rescues Behavioral Deficits in a Mouse Model of Rett Syndrome.
Yuan ZF, Mao SS, Shen J, Jiang LH, Xu L, Xu JL, Gao F
Frontiers in neuroscience 2020;14:20
Frontiers in neuroscience 2020;14:20
Fatigue-induced change in T-system excitability and its major cause in rat fast-twitch skeletal muscle in vivo.
Watanabe D, Wada M
The Journal of physiology 2020 Nov;598(22):5195-5211
The Journal of physiology 2020 Nov;598(22):5195-5211
Isoform-specific Na,K-ATPase and membrane cholesterol remodeling in motor endplates in distinct mouse models of myodystrophy.
Kravtsova VV, Bouzinova EV, Chibalin AV, Matchkov VV, Krivoi II
American journal of physiology. Cell physiology 2020 May 1;318(5):C1030-C1041
American journal of physiology. Cell physiology 2020 May 1;318(5):C1030-C1041
Cycling with blood flow restriction improves performance and muscle K(+) regulation and alters the effect of anti-oxidant infusion in humans.
Christiansen D, Eibye KH, Rasmussen V, Voldbye HM, Thomassen M, Nyberg M, Gunnarsson TGP, Skovgaard C, Lindskrog MS, Bishop DJ, Hostrup M, Bangsbo J
The Journal of physiology 2019 May;597(9):2421-2444
The Journal of physiology 2019 May;597(9):2421-2444
Axial Tubule Junctions Activate Atrial Ca(2+) Release Across Species.
Brandenburg S, Pawlowitz J, Fakuade FE, Kownatzki-Danger D, Kohl T, Mitronova GY, Scardigli M, Neef J, Schmidt C, Wiedmann F, Pavone FS, Sacconi L, Kutschka I, Sossalla S, Moser T, Voigt N, Lehnart SE
Frontiers in physiology 2018;9:1227
Frontiers in physiology 2018;9:1227
The effect of repeated periods of speed endurance training on performance, running economy, and muscle adaptations.
Skovgaard C, Almquist NW, Bangsbo J
Scandinavian journal of medicine & science in sports 2018 Feb;28(2):381-390
Scandinavian journal of medicine & science in sports 2018 Feb;28(2):381-390
Effect of tapering after a period of high-volume sprint interval training on running performance and muscular adaptations in moderately trained runners.
Skovgaard C, Almquist NW, Kvorning T, Christensen PM, Bangsbo J
Journal of applied physiology (Bethesda, Md. : 1985) 2018 Feb 1;124(2):259-267
Journal of applied physiology (Bethesda, Md. : 1985) 2018 Feb 1;124(2):259-267
Cold-water immersion after training sessions: effects on fiber type-specific adaptations in muscle K(+) transport proteins to sprint-interval training in men.
Christiansen D, Bishop DJ, Broatch JR, Bangsbo J, McKenna MJ, Murphy RM
Journal of applied physiology (Bethesda, Md. : 1985) 2018 Aug 1;125(2):429-444
Journal of applied physiology (Bethesda, Md. : 1985) 2018 Aug 1;125(2):429-444
Effect of increased and maintained frequency of speed endurance training on performance and muscle adaptations in runners.
Skovgaard C, Almquist NW, Bangsbo J
Journal of applied physiology (Bethesda, Md. : 1985) 2017 Jan 1;122(1):48-59
Journal of applied physiology (Bethesda, Md. : 1985) 2017 Jan 1;122(1):48-59
Over-expression of microRNA-1 causes arrhythmia by disturbing intracellular trafficking system.
Su X, Liang H, Wang H, Chen G, Jiang H, Wu Q, Liu T, Liu Q, Yu T, Gu Y, Yang B, Shan H
Scientific reports 2017 Apr 11;7:46259
Scientific reports 2017 Apr 11;7:46259
Effect of formoterol, a long-acting β2-adrenergic agonist, on muscle strength and power output, metabolism, and fatigue during maximal sprinting in men.
Kalsen A, Hostrup M, Backer V, Bangsbo J
American journal of physiology. Regulatory, integrative and comparative physiology 2016 Jun 1;310(11):R1312-21
American journal of physiology. Regulatory, integrative and comparative physiology 2016 Jun 1;310(11):R1312-21
Distinct α2 Na,K-ATPase membrane pools are differently involved in early skeletal muscle remodeling during disuse.
Kravtsova VV, Petrov AM, Matchkov VV, Bouzinova EV, Vasiliev AN, Benziane B, Zefirov AL, Chibalin AV, Heiny JA, Krivoi II
The Journal of general physiology 2016 Feb;147(2):175-88
The Journal of general physiology 2016 Feb;147(2):175-88
Muscle variables of importance for physiological performance in competitive football.
Mohr M, Thomassen M, Girard O, Racinais S, Nybo L
European journal of applied physiology 2016 Feb;116(2):251-62
European journal of applied physiology 2016 Feb;116(2):251-62
Intensive training and reduced volume increases muscle FXYD1 expression and phosphorylation at rest and during exercise in athletes.
Thomassen M, Gunnarsson TP, Christensen PM, Pavlovic D, Shattock MJ, Bangsbo J
American journal of physiology. Regulatory, integrative and comparative physiology 2016 Apr 1;310(7):R659-69
American journal of physiology. Regulatory, integrative and comparative physiology 2016 Apr 1;310(7):R659-69
Mechanisms underlying enhancements in muscle force and power output during maximal cycle ergometer exercise induced by chronic β2-adrenergic stimulation in men.
Hostrup M, Kalsen A, Onslev J, Jessen S, Haase C, Habib S, Ørtenblad N, Backer V, Bangsbo J
Journal of applied physiology (Bethesda, Md. : 1985) 2015 Sep 1;119(5):475-86
Journal of applied physiology (Bethesda, Md. : 1985) 2015 Sep 1;119(5):475-86
Phospholemman is not required for the acute stimulation of Na⁺-K⁺-ATPase α₂-activity during skeletal muscle fatigue.
Manoharan P, Radzyukevich TL, Hakim Javadi H, Stiner CA, Landero Figueroa JA, Lingrel JB, Heiny JA
American journal of physiology. Cell physiology 2015 Dec 15;309(12):C813-22
American journal of physiology. Cell physiology 2015 Dec 15;309(12):C813-22
Concurrent speed endurance and resistance training improves performance, running economy, and muscle NHE1 in moderately trained runners.
Skovgaard C, Christensen PM, Larsen S, Andersen TR, Thomassen M, Bangsbo J
Journal of applied physiology (Bethesda, Md. : 1985) 2014 Nov 15;117(10):1097-109
Journal of applied physiology (Bethesda, Md. : 1985) 2014 Nov 15;117(10):1097-109
Fibre type-specific change in FXYD1 phosphorylation during acute intense exercise in humans.
Thomassen M, Murphy RM, Bangsbo J
The Journal of physiology 2013 Mar 15;591(6):1523-33
The Journal of physiology 2013 Mar 15;591(6):1523-33
Chronic nicotine modifies skeletal muscle Na,K-ATPase activity through its interaction with the nicotinic acetylcholine receptor and phospholemman.
Chibalin AV, Heiny JA, Benziane B, Prokofiev AV, Vasiliev AV, Kravtsova VV, Krivoi II
PloS one 2012;7(3):e33719
PloS one 2012;7(3):e33719
Influence of chronic and acute spinal cord injury on skeletal muscle Na+-K+-ATPase and phospholemman expression in humans.
Boon H, Kostovski E, Pirkmajer S, Song M, Lubarski I, Iversen PO, Hjeltnes N, Widegren U, Chibalin AV
American journal of physiology. Endocrinology and metabolism 2012 Apr 1;302(7):E864-71
American journal of physiology. Endocrinology and metabolism 2012 Apr 1;302(7):E864-71
Effect of exercise and training on phospholemman phosphorylation in human skeletal muscle.
Benziane B, Widegren U, Pirkmajer S, Henriksson J, Stepto NK, Chibalin AV
American journal of physiology. Endocrinology and metabolism 2011 Sep;301(3):E456-66
American journal of physiology. Endocrinology and metabolism 2011 Sep;301(3):E456-66
The nicotinic acetylcholine receptor and the Na,K-ATPase alpha2 isoform interact to regulate membrane electrogenesis in skeletal muscle.
Heiny JA, Kravtsova VV, Mandel F, Radzyukevich TL, Benziane B, Prokofiev AV, Pedersen SE, Chibalin AV, Krivoi II
The Journal of biological chemistry 2010 Sep 10;285(37):28614-26
The Journal of biological chemistry 2010 Sep 10;285(37):28614-26
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Phospholemman/FXYD1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Phospholemman/FXYD1. This antibody recognizes human,mouse,rat antigen. The Phospholemman/FXYD1 antibody has been validated for the following applications: ELISA, WB analysis.
