Antibody data
- Antibody Data
- Antigen structure
- References [20]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- 15571-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15571-1-AP, RRID:AB_2106746
- Product name
- Flotillin 1 antibody
- Antibody type
- Polyclonal
- Description
- Flotillin 1 antibody (Cat. #15571-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Neuronal Exosomes Secreted under Oxygen-Glucose Deprivation/Reperfusion Presenting Differentially Expressed miRNAs and Affecting Neuronal Survival and Neurite Outgrowth.
Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway.
NCBP3/SNHG6 inhibits GBX2 transcription in a histone modification manner to facilitate the malignant biological behaviour of glioma cells.
EVs Containing Host Restriction Factor IFITM3 Inhibited ZIKV Infection of Fetuses in Pregnant Mice through Trans-placenta Delivery.
GBA Mutations Influence the Release and Pathological Effects of Small Extracellular Vesicles from Fibroblasts of Patients with Parkinson's Disease.
Bone marrow macrophage-derived exosomal miR-143-5p contributes to insulin resistance in hepatocytes by repressing MKP5.
Circulating Exosomal miRNAs as Novel Biomarkers for Stable Coronary Artery Disease.
Circulating Donor Heart Exosome Profiling Enables Noninvasive Detection of Antibody-mediated Rejection.
Discovery of new receptors regulating luteinizing hormone and follicle-stimulating hormone secretion by bovine gonadotrophs to explore a new paradigm for mechanisms regulating reproduction.
In vivo reduction of striatal D1R by RNA interference alters expression of D1R signaling-related proteins and enhances methamphetamine addiction in male rats.
Syncytiotrophoblast extracellular microvesicle profiles in maternal circulation for noninvasive diagnosis of preeclampsia.
A new small cell lung cancer biomarker identified by Cell-SELEX generated aptamers.
Shenmai injection maintains blood-brain barrier integrity following focal cerebral ischemia via modulating the expression and trafficking of occludin in lipid rafts.
Exosomes Induce Fibroblast Differentiation into Cancer-Associated Fibroblasts through TGFβ Signaling.
Differential protein analysis of serum exosomes post-intravenous immunoglobulin therapy in patients with Kawasaki disease.
Identification and characterization of the lamprey Flotillin-1 gene with a role in cell adhesion.
Lost region in amyloid precursor protein (APP) through TALEN-mediated genome editing alters mitochondrial morphology.
Flotillin-2 promotes metastasis of nasopharyngeal carcinoma by activating NF-κB and PI3K/Akt3 signaling pathways.
TNFα triggers release of extracellular vesicles containing TNFR1 and TRADD, which can modulate TNFα responses of the parental cells.
Translocation of mixed lineage kinase domain-like protein to plasma membrane leads to necrotic cell death.
Chiang CS, Fu SJ, Hsu CL, Jeng CJ, Tang CY, Huang YS, Tang SC
Neuromolecular medicine 2021 Sep;23(3):404-415
Neuromolecular medicine 2021 Sep;23(3):404-415
Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway.
Gao X, Wang Y, Lu F, Chen X, Yang D, Cao Y, Zhang W, Chen J, Zheng L, Wang G, Fu M, Ma L, Song Y, Zhan Q
Journal of extracellular vesicles 2021 Mar;10(5):e12060
Journal of extracellular vesicles 2021 Mar;10(5):e12060
NCBP3/SNHG6 inhibits GBX2 transcription in a histone modification manner to facilitate the malignant biological behaviour of glioma cells.
Li X, Zhang F, Ma J, Ruan X, Liu X, Zheng J, Liu Y, Cao S, Shen S, Shao L, Cai H, Li Z, Xue Y
RNA biology 2021 Jan;18(1):47-63
RNA biology 2021 Jan;18(1):47-63
EVs Containing Host Restriction Factor IFITM3 Inhibited ZIKV Infection of Fetuses in Pregnant Mice through Trans-placenta Delivery.
Zou X, Yuan M, Zhang T, Zheng N, Wu Z
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Jan 6;29(1):176-190
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Jan 6;29(1):176-190
GBA Mutations Influence the Release and Pathological Effects of Small Extracellular Vesicles from Fibroblasts of Patients with Parkinson's Disease.
Cerri S, Ghezzi C, Ongari G, Croce S, Avenali M, Zangaglia R, Di Monte DA, Valente EM, Blandini F
International journal of molecular sciences 2021 Feb 23;22(4)
International journal of molecular sciences 2021 Feb 23;22(4)
Bone marrow macrophage-derived exosomal miR-143-5p contributes to insulin resistance in hepatocytes by repressing MKP5.
Li L, Zuo H, Huang X, Shen T, Tang W, Zhang X, An T, Dou L, Li J
Cell proliferation 2021 Dec;54(12):e13140
Cell proliferation 2021 Dec;54(12):e13140
Circulating Exosomal miRNAs as Novel Biomarkers for Stable Coronary Artery Disease.
Zhang P, Liang T, Chen Y, Wang X, Wu T, Xie Z, Luo J, Yu Y, Yu H
BioMed research international 2020;2020:3593962
BioMed research international 2020;2020:3593962
Circulating Donor Heart Exosome Profiling Enables Noninvasive Detection of Antibody-mediated Rejection.
Hu RW, Korutla L, Reddy S, Harmon J, Zielinski PD, Bueker A, Molina M, Romano C, Margulies K, McLean R, Lal P, Vallabhajosyula P
Transplantation direct 2020 Nov;6(11):e615
Transplantation direct 2020 Nov;6(11):e615
Discovery of new receptors regulating luteinizing hormone and follicle-stimulating hormone secretion by bovine gonadotrophs to explore a new paradigm for mechanisms regulating reproduction.
Kadokawa H
The Journal of reproduction and development 2020 Aug 20;66(4):291-297
The Journal of reproduction and development 2020 Aug 20;66(4):291-297
In vivo reduction of striatal D1R by RNA interference alters expression of D1R signaling-related proteins and enhances methamphetamine addiction in male rats.
Kreisler AD, Terranova MJ, Somkuwar SS, Purohit DC, Wang S, Head BP, Mandyam CD
Brain structure & function 2020 Apr;225(3):1073-1088
Brain structure & function 2020 Apr;225(3):1073-1088
Syncytiotrophoblast extracellular microvesicle profiles in maternal circulation for noninvasive diagnosis of preeclampsia.
Levine L, Habertheuer A, Ram C, Korutla L, Schwartz N, Hu RW, Reddy S, Freas A, Zielinski PD, Harmon J, Molugu SK, Parry S, Vallabhajosyula P
Scientific reports 2020 Apr 14;10(1):6398
Scientific reports 2020 Apr 14;10(1):6398
A new small cell lung cancer biomarker identified by Cell-SELEX generated aptamers.
Zhou W, Zhao L, Yuan H, Xu L, Tan W, Song Y, Fang X
Experimental cell research 2019 Sep 15;382(2):111478
Experimental cell research 2019 Sep 15;382(2):111478
Shenmai injection maintains blood-brain barrier integrity following focal cerebral ischemia via modulating the expression and trafficking of occludin in lipid rafts.
Xu H, Liu Y, Wang D, Zhang Z
Journal of ethnopharmacology 2019 Jun 12;237:55-63
Journal of ethnopharmacology 2019 Jun 12;237:55-63
Exosomes Induce Fibroblast Differentiation into Cancer-Associated Fibroblasts through TGFβ Signaling.
Ringuette Goulet C, Bernard G, Tremblay S, Chabaud S, Bolduc S, Pouliot F
Molecular cancer research : MCR 2018 Jul;16(7):1196-1204
Molecular cancer research : MCR 2018 Jul;16(7):1196-1204
Differential protein analysis of serum exosomes post-intravenous immunoglobulin therapy in patients with Kawasaki disease.
Zhang L, Song QF, Jin JJ, Huang P, Wang ZP, Xie XF, Gu XQ, Gao XJ, Jia HL
Cardiology in the young 2017 Nov;27(9):1786-1796
Cardiology in the young 2017 Nov;27(9):1786-1796
Identification and characterization of the lamprey Flotillin-1 gene with a role in cell adhesion.
Xu R, Song X, Su P, Pang Y, Li Q
Fish & shellfish immunology 2017 Dec;71:286-294
Fish & shellfish immunology 2017 Dec;71:286-294
Lost region in amyloid precursor protein (APP) through TALEN-mediated genome editing alters mitochondrial morphology.
Wang Y, Wu F, Pan H, Zheng W, Feng C, Wang Y, Deng Z, Wang L, Luo J, Chen S
Scientific reports 2016 Feb 29;6:22244
Scientific reports 2016 Feb 29;6:22244
Flotillin-2 promotes metastasis of nasopharyngeal carcinoma by activating NF-κB and PI3K/Akt3 signaling pathways.
Liu J, Huang W, Ren C, Wen Q, Liu W, Yang X, Wang L, Zhu B, Zeng L, Feng X, Zhang C, Chen H, Jia W, Zhang L, Xia X, Chen Y
Scientific reports 2015 Jul 24;5:11614
Scientific reports 2015 Jul 24;5:11614
TNFα triggers release of extracellular vesicles containing TNFR1 and TRADD, which can modulate TNFα responses of the parental cells.
Sohda M, Misumi Y, Oda K
Archives of biochemistry and biophysics 2015 Dec 1;587:31-7
Archives of biochemistry and biophysics 2015 Dec 1;587:31-7
Translocation of mixed lineage kinase domain-like protein to plasma membrane leads to necrotic cell death.
Chen X, Li W, Ren J, Huang D, He WT, Song Y, Yang C, Li W, Zheng X, Chen P, Han J
Cell research 2014 Jan;24(1):105-21
Cell research 2014 Jan;24(1):105-21
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse heart tissue were subjected to SDS PAGE followed by western blot with 15571-1-AP(FLOT1 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using FLOT1 antibody 15571-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line