Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
- Flow cytometry [1]
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Validation data
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- Product number
- AF5825 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal CX3CR1 Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects human and mouse CX3CR1 in direct ELISAs and Western blots.
- Reactivity
- Human, Mouse
- Host
- Goat
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Migration-based selections of antibodies that convert bone marrow into trafficking microglia-like cells that reduce brain amyloid β.
Novel adherent CD11b+ Gr-1+ tumor-infiltrating cells initiate an immunosuppressive tumor microenvironment.
Hepatectomy leads to loss of TRAIL-expressing liver NK cells via downregulation of the CXCL9-CXCR3 axis in mice.
MicroRNA-101a regulates microglial morphology and inflammation.
A CCR2+ myeloid cell niche required for pancreatic β cell growth.
MKEY, a Peptide Inhibitor of CXCL4-CCL5 Heterodimer Formation, Protects Against Stroke in Mice.
Selective suppression of the α isoform of p38 MAPK rescues late-stage tau pathology.
Syndecan-1 in the mouse parietal peritoneum microcirculation in inflammation.
Fractalkine is a novel human adipochemokine associated with type 2 diabetes.
Han KH, Arlian BM, Macauley MS, Paulson JC, Lerner RA
Proceedings of the National Academy of Sciences of the United States of America 2018 Jan 16;115(3):E372-E381
Proceedings of the National Academy of Sciences of the United States of America 2018 Jan 16;115(3):E372-E381
Novel adherent CD11b+ Gr-1+ tumor-infiltrating cells initiate an immunosuppressive tumor microenvironment.
Tsubaki T, Kadonosono T, Sakurai S, Shiozawa T, Goto T, Sakai S, Kuchimaru T, Sakamoto T, Watanabe H, Kondoh G, Kizaka-Kondoh S
Oncotarget 2018 Feb 16;9(13):11209-11226
Oncotarget 2018 Feb 16;9(13):11209-11226
Hepatectomy leads to loss of TRAIL-expressing liver NK cells via downregulation of the CXCL9-CXCR3 axis in mice.
Yano T, Ohira M, Nakano R, Tanaka Y, Ohdan H
PloS one 2017;12(10):e0186997
PloS one 2017;12(10):e0186997
MicroRNA-101a regulates microglial morphology and inflammation.
Saika R, Sakuma H, Noto D, Yamaguchi S, Yamamura T, Miyake S
Journal of neuroinflammation 2017 May 30;14(1):109
Journal of neuroinflammation 2017 May 30;14(1):109
A CCR2+ myeloid cell niche required for pancreatic β cell growth.
Mussar K, Pardike S, Hohl TM, Hardiman G, Cirulli V, Crisa L
JCI insight 2017 Aug 3;2(15)
JCI insight 2017 Aug 3;2(15)
MKEY, a Peptide Inhibitor of CXCL4-CCL5 Heterodimer Formation, Protects Against Stroke in Mice.
Fan Y, Xiong X, Zhang Y, Yan D, Jian Z, Xu B, Zhao H
Journal of the American Heart Association 2016 Sep 15;5(9)
Journal of the American Heart Association 2016 Sep 15;5(9)
Selective suppression of the α isoform of p38 MAPK rescues late-stage tau pathology.
Maphis N, Jiang S, Xu G, Kokiko-Cochran ON, Roy SM, Van Eldik LJ, Watterson DM, Lamb BT, Bhaskar K
Alzheimer's research & therapy 2016 Dec 15;8(1):54
Alzheimer's research & therapy 2016 Dec 15;8(1):54
Syndecan-1 in the mouse parietal peritoneum microcirculation in inflammation.
Kowalewska PM, Patrick AL, Fox-Robichaud AE
PloS one 2014;9(9):e104537
PloS one 2014;9(9):e104537
Fractalkine is a novel human adipochemokine associated with type 2 diabetes.
Shah R, Hinkle CC, Ferguson JF, Mehta NN, Li M, Qu L, Lu Y, Putt ME, Ahima RS, Reilly MP
Diabetes 2011 May;60(5):1512-8
Diabetes 2011 May;60(5):1512-8
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of Human and Mouse CX3CR1 by Western Blot. Detection of Human and Mouse CX3CR1 by Western Blot.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of CX3CR1 in M1 Mouse Cell Line by Flow Cytometry. Detection of CX3CR1 in M1 Mouse Cell Line by Flow Cytometry.