Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- 341605 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#341605, RRID:AB_1626276
- Product name
- FITC anti-human CX3CR1
- Antibody type
- Monoclonal
- Antigen
- CX3CR1-EGFP fusion protein
- Description
- CX3CR1 is a G-protein- coupled seven-transmembrane chemokine receptor, also called GPR13 or V28. It is expressed on NK cells, T cell subset, monocytes/macrophages, dendritic cells, and some malignant epithelial cells. CX3CL1 (known as fractalkine, neurotactin) is the ligand of CX3CR1. CX3CL1 is a unique transmembrane molecule with a CX3C-motif chemokine domain and a mucin-like stalk. CX3CL1 is expressed by activated-endothelial cells, neurons, and astrocytes. The interaction of CX3CR1 and its ligand mediates cell firm adhesion and migration.
- Reactivity
- Human
- Host
- Rat
- Conjugate
- Green dye
- Isotype
- IgG
- Vial size
- 25 tests
- Storage
- The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Submitted references Cytomegalovirus-induced effector T cells cause endothelial cell damage.
Human virus-specific effector-type T cells accumulate in blood but not in lymph nodes.
van de Berg PJ, Yong SL, Remmerswaal EB, van Lier RA, ten Berge IJ
Clinical and vaccine immunology : CVI 2012 May;19(5):772-9
Clinical and vaccine immunology : CVI 2012 May;19(5):772-9
Human virus-specific effector-type T cells accumulate in blood but not in lymph nodes.
Remmerswaal EB, Havenith SH, Idu MM, van Leeuwen EM, van Donselaar KA, Ten Brinke A, van der Bom-Baylon N, Bemelman FJ, van Lier RA, Ten Berge IJ
Blood 2012 Feb 16;119(7):1702-12
Blood 2012 Feb 16;119(7):1702-12
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- Human peripheral blood lymphocytes stained with 2A9-1 FITC and anti-FCD3 (UCHT1) APC
- Conjugate
- Green dye