HPA001562

antibody from Atlas Antibodies

Targeting: ATF3

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

HPA001562

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA001562, RRID:AB_1078233

Product name

Anti-ATF3

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human ATF3, Gene description: activating transcription factor 3, Validated applications: IHC, ICC, Uniprot ID: P18847, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.2 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

Electroacupuncture alleviates paclitaxel-induced peripheral neuropathy by reducing CCL2-mediated macrophage infiltration in sensory ganglia and sciatic nerve

Li Y, Xu R, Chen M, Zheng K, Nie H, Yin C, Liu B, Tai Y, Du J, Wang J, Fang J, Liu B
Chinese Medicine 2025;20(1)

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Effects of novel flame retardants tris(1,3-dichloro-2-propyl) phosphate (TDCIPP) and triphenyl phosphate (TPhP) on function and homeostasis in human and rat pancreatic beta-cell lines

Pavlíková N, Šrámek J, Němcová V, Bajard L
Archives of Toxicology 2024;98(11):3859-3874

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Development of a 3-dimensional organotypic model with characteristics of peripheral sensory nerves

Koyanagi M, Ogido R, Moriya A, Saigo M, Ihida S, Teranishi T, Kawada J, Katsuno T, Matsubara K, Terada T, Yamashita A, Imai S
Cell Reports Methods 2024;4(8):100835

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Molecular profiling of NOD mouse islets reveals a novel regulator of insulitis onset

Mathisen A, Vacaru A, Unger L, Lamba E, Mardare O, Daian L, Ghila L, Vacaru A, Chera S
Scientific Reports 2024;14(1)

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Injury distance limits the transcriptional response to spinal injury.

Wang Z, Kumaran M, Batsel E, Testor-Cabrera S, Beine Z, Ribelles AA, Tsoulfas P, Venkatesh I, Blackmore MG
bioRxiv : the preprint server for biology 2024 Jun 5;

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Inflammatory, metabolic, and sex-dependent gene-regulatory dynamics of microglia and macrophages in neonatal hippocampus after hypoxia-ischemia.

Di Martino E, Ambikan A, Ramsköld D, Umekawa T, Giatrellis S, Vacondio D, Romero AL, Galán MG, Sandberg R, Ådén U, Lauschke VM, Neogi U, Blomgren K, Kele J
iScience 2024 Apr 19;27(4):109346

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Anti-Inflammatory Activity of Synaptamide in the Peripheral Nervous System in a Model of Sciatic Nerve Injury

Starinets A, Tyrtyshnaia A, Manzhulo I
International Journal of Molecular Sciences 2023;24(7):6273

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RNA-Seq Reveals Sex Differences in Gene Expression during Peripheral Neuropathic Inflammation and in Pain Relief from a COX-2 Inhibiting Theranostic Nanoemulsion

Deal B, Phillips K, Crelli C, Janjic J, Pollock J
International Journal of Molecular Sciences 2023;24(11):9163

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High-intensity swimming alleviates nociception and neuroinflammation in a mouse model of chronic post-ischemia pain by activating the resolvin E1-chemerin receptor 23 axis in the spinal cord

Jia X, Li Z, Shen X, Zhang Y, Zhang L, Zhang L
Neural Regeneration Research 2023;18(11):2535-2542

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Genome-Wide Expression Profiling by RNA-Sequencing in Spinal Cord Dorsal Horn of a Rat Chronic Postsurgical Pain Model to Explore Potential Mechanisms Involved in Chronic Pain

Xu R, Wang J, Nie H, Zeng D, Yin C, Li Y, Wei H, Liu B, Tai Y, Hu Q, Shao X, Fang J, Liu B
Journal of Pain Research 2022;Volume 15

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Linalyl Acetate Ameliorates Mechanical Hyperalgesia Through Suppressing Inflammation by TSLP/IL-33 Signaling

Lu Y, Lu C, Huang C, Tsai H, Wang W, Zhang Z, Wu C
Neurochemical Research 2022;47(12):3805-3816

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Gene Expression Profiling of Contralateral Dorsal Root Ganglia Associated with Mirror-Image Pain in a Rat Model of Complex Regional Pain Syndrome Type-I

Nie H, Liu B, Yin C, Chen R, Wang J, Zeng D, Tai Y, Xie J, He D, Liu B
Journal of Pain Research 2021;Volume 14

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Decreased expression of ATF3, orchestrated by β-catenin/TCF3, miR-17-5p and HOXA11-AS, promoted gastric cancer progression via increased β-catenin and CEMIP

Xie G, Dong P, Chen H, Xu L, Liu Y, Ma Y, Zheng Y, Yang J, Zhou Y, Chen L, Shen L
Experimental & Molecular Medicine 2021;53(11):1706-1722

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Exercise-induced angiogenesis is dependent on metabolically primed ATF3/4+ endothelial cells

Fan Z, Turiel G, Ardicoglu R, Ghobrial M, Masschelein E, Kocijan T, Zhang J, Tan G, Fitzgerald G, Gorski T, Alvarado-Diaz A, Gilardoni P, Adams C, Ghesquière B, De Bock K
Cell Metabolism 2021;33(9):1793-1807.e9

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Increased Expression of Thymic Stromal Lymphopoietin in Chronic Constriction Injury of Rat Nerve

Wu C, Lu C, Huang C, Wu M, Lu Y
International Journal of Molecular Sciences 2021;22(13):7105

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Transcriptome profiling of long noncoding RNAs and mRNAs in spinal cord of a rat model of paclitaxel-induced peripheral neuropathy identifies potential mechanisms mediating neuroinflammation and pain

Li Y, Yin C, Liu B, Nie H, Wang J, Zeng D, Chen R, He X, Fang J, Du J, Liang Y, Jiang Y, Fang J, Liu B
Journal of Neuroinflammation 2021;18(1)

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ATF3 deficiency impairs the proliferative–secretory phase transition and decidualization in RIF patients

Wang Z, Liu Y, Liu J, Kong N, Jiang Y, Jiang R, Zhen X, Zhou J, Li C, Sun H, Yan G
Cell Death & Disease 2021;12(4)

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Tissue-resident M2 macrophages directly contact primary sensory neurons in the sensory ganglia after nerve injury.

Iwai H, Ataka K, Suzuki H, Dhar A, Kuramoto E, Yamanaka A, Goto T
Journal of neuroinflammation 2021 Oct 13;18(1):227

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Activating transcription factor 3 coordinates differentiation of cardiac and hematopoietic progenitors by regulating glucose metabolism

Yin H, Yan L, Liu Q, Peng Z, Zhang C, Xia Y, Su D, Gu A, Zhou Y
Science Advances 2020;6(19)

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The endogenous neuronal complement inhibitor SRPX2 protects against complement-mediated synapse elimination during development

Cong Q, Soteros B, Wollet M, Kim J, Sia G
Nature Neuroscience 2020;23(9):1067-1078

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Atrophy and Death of Nonpeptidergic and Peptidergic Nociceptive Neurons in SIV Infection

Robinson J, Guenthner G, Warfield R, Kublin J, Smith M, Shekarabi M, Miller A, Burdo T
The American Journal of Pathology 2020;190(7):1530-1544

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Transcriptional Reprogramming of Distinct Peripheral Sensory Neuron Subtypes after Axonal Injury

Renthal W, Tochitsky I, Yang L, Cheng Y, Li E, Kawaguchi R, Geschwind D, Woolf C
Neuron 2020;108(1):128-144.e9

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Interference with SRF expression in skeletal muscles reduces peripheral nerve regeneration in mice.

Wanner R, Knöll B
Scientific reports 2020 Mar 24;10(1):5281

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Single-Cell RNA Transcriptome Helps Define the Limbal/Corneal Epithelial Stem/Early Transit Amplifying Cells and How Autophagy Affects This Population

Kaplan N, Wang J, Wray B, Patel P, Yang W, Peng H, Lavker R
Investigative Opthalmology & Visual Science 2019;60(10):3570

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Sensory lesioning induces microglial synapse elimination via ADAM10 and fractalkine signaling

Gunner G, Cheadle L, Johnson K, Ayata P, Badimon A, Mondo E, Nagy M, Liu L, Bemiller S, Kim K, Lira S, Lamb B, Tapper A, Ransohoff R, Greenberg M, Schaefer A, Schafer D
Nature Neuroscience 2019;22(7):1075-1088

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Inhibiting the integrated stress response pathway prevents aberrant chondrocyte differentiation thereby alleviating chondrodysplasia

Wang C, Tan Z, Niu B, Tsang K, Tai A, Chan W, Lo R, Leung K, Dung N, Itoh N, Zhang M, Chan D, Cheah K
eLife 2018;7

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Defining the Transcriptional Targets of Leptin Reveals a Role for Atf3 in Leptin Action

Allison M, Pan W, MacKenzie A, Patterson C, Shah K, Barnes T, Cheng W, Rupp A, Olson D, Myers M
Diabetes 2018;67(6):1093-1104

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ATF3 represses PINK1 gene transcription in lung epithelial cells to control mitochondrial homeostasis

Bueno M, Brands J, Voltz L, Fiedler K, Mays B, St. Croix C, Sembrat J, Mallampalli R, Rojas M, Mora A
Aging Cell 2018;17(2)

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The stress response gene ATF3 is a direct target of the Wnt/β-catenin pathway and inhibits the invasion and migration of HCT116 human colorectal cancer cells

Liu C, Inoue M, Uchida Y, Edagawa M, Hirata M, Mitamura J, Miyamoto D, Taketani K, Sekine S, Kawauchi J, Kitajima S
PLOS ONE 2018;13(7):e0194160

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Palmitate Increases β-site AβPP-Cleavage Enzyme 1 Activity and Amyloid-β Genesis by Evoking Endoplasmic Reticulum Stress and Subsequent C/EBP Homologous Protein Activation

Marwarha G, Rostad S, Lilek J, Kleinjan M, Schommer J, Ghribi O, Schreurs B
Journal of Alzheimer’s Disease 2017;57(3):907-925

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Activating transcription factor 3 promotes embryo attachment via up-regulation of leukemia inhibitory factor in vitro

Cheng X, Liu J, Shan H, Sun L, Huang C, Yan Q, Jiang R, Ding L, Jiang Y, Zhou J, Yan G, Sun H
Reproductive Biology and Endocrinology 2017;15(1)

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Atf3 mutant mice show reduced axon regeneration and impaired regeneration-associated gene induction after peripheral nerve injury.

Gey M, Wanner R, Schilling C, Pedro MT, Sinske D, Knöll B
Open biology 2016 Aug;6(8)

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Role of Activating Transcription Factor 3 (ATF3) in Endoplasmic Reticulum (ER) Stress-induced Sensitization of p53-deficient Human Colon Cancer Cells to Tumor Necrosis Factor (TNF)-related Apoptosis-inducing Ligand (TRAIL)-mediated Apoptosis through Up-regulation of Death Receptor 5 (DR5) by Zerumbone and Celecoxib

Edagawa M, Kawauchi J, Hirata M, Goshima H, Inoue M, Okamoto T, Murakami A, Maehara Y, Kitajima S
Journal of Biological Chemistry 2014;289(31):21544-21561

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The Activating Transcription Factor 3 Protein Suppresses the Oncogenic Function of Mutant p53 Proteins

Wei S, Wang H, Lu C, Malmut S, Zhang J, Ren S, Yu G, Wang W, Tang D, Yan C
Journal of Biological Chemistry 2014;289(13):8947-8959

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Immunohistochemical Detection of Activating Transcription Factor 3, a Hub of the Cellular Adaptive–Response Network

Hai T, Jalgaonkar S, Wolford C, Yin X
2011;490

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Opposing roles for calcineurin and ATF3 in squamous skin cancer

Wu X, Nguyen B, Dziunycz P, Chang S, Brooks Y, Lefort K, Hofbauer G, Dotto G
Nature 2010;465(7296):368-372