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- Antigen structure
- References [7]
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- Western blot [1]
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- Product number
- 21856-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21856-1-AP, RRID:AB_10836934
- Product name
- KIDINS220 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated KIDINS220 antibody (Cat. #21856-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references IgLON5 deficiency produces behavioral alterations in a knockout mouse model.
Kidins220 and Aiolos promote thymic iNKT cell development by reducing TCR signals.
Patients' IgLON5 autoantibodies interfere with IgLON5-protein interactions.
Regulation of the endosomal SNX27-retromer by OTULIN.
Kidins220/ARMS binds to the B cell antigen receptor and regulates B cell development and activation.
A unique PDZ domain and arrestin-like fold interaction reveals mechanistic details of endocytic recycling by SNX27-retromer.
A global analysis of SNX27-retromer assembly and cargo specificity reveals a function in glucose and metal ion transport.
Landa J, Serafim AB, Alba M, Maudes E, Molina-Porcel L, Garcia-Serra A, Mannara F, Dalmau J, Graus F, Sabater L
Frontiers in immunology 2024;15:1347948
Frontiers in immunology 2024;15:1347948
Kidins220 and Aiolos promote thymic iNKT cell development by reducing TCR signals.
Herr LA, Fiala GJ, Sagar, Schaffer AM, Hummel JF, Zintchenko M, Raute K, Velasco Cárdenas RM, Heizmann B, Ebert K, Fehrenbach K, Janowska I, Chan S, Tanriver Y, Minguet S, Schamel WW
Science advances 2024 Mar 15;10(11):eadj2802
Science advances 2024 Mar 15;10(11):eadj2802
Patients' IgLON5 autoantibodies interfere with IgLON5-protein interactions.
Landa J, Serafim AB, Gaig C, Saiz A, Koneczny I, Hoftberger R, Santamaria J, Dalmau J, Graus F, Sabater L
Frontiers in immunology 2023;14:1151574
Frontiers in immunology 2023;14:1151574
Regulation of the endosomal SNX27-retromer by OTULIN.
Stangl A, Elliott PR, Pinto-Fernandez A, Bonham S, Harrison L, Schaub A, Kutzner K, Keusekotten K, Pfluger PT, El Oualid F, Kessler BM, Komander D, Krappmann D
Nature communications 2019 Sep 20;10(1):4320
Nature communications 2019 Sep 20;10(1):4320
Kidins220/ARMS binds to the B cell antigen receptor and regulates B cell development and activation.
Fiala GJ, Janowska I, Prutek F, Hobeika E, Satapathy A, Sprenger A, Plum T, Seidl M, Dengjel J, Reth M, Cesca F, Brummer T, Minguet S, Schamel WW
The Journal of experimental medicine 2015 Sep 21;212(10):1693-708
The Journal of experimental medicine 2015 Sep 21;212(10):1693-708
A unique PDZ domain and arrestin-like fold interaction reveals mechanistic details of endocytic recycling by SNX27-retromer.
Gallon M, Clairfeuille T, Steinberg F, Mas C, Ghai R, Sessions RB, Teasdale RD, Collins BM, Cullen PJ
Proceedings of the National Academy of Sciences of the United States of America 2014 Sep 2;111(35):E3604-13
Proceedings of the National Academy of Sciences of the United States of America 2014 Sep 2;111(35):E3604-13
A global analysis of SNX27-retromer assembly and cargo specificity reveals a function in glucose and metal ion transport.
Steinberg F, Gallon M, Winfield M, Thomas EC, Bell AJ, Heesom KJ, Tavaré JM, Cullen PJ
Nature cell biology 2013 May;15(5):461-71
Nature cell biology 2013 May;15(5):461-71
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The KIDINS220 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human KIDINS220. This antibody recognizes human, mouse, rat antigen. The KIDINS220 antibody has been validated for the following applications: ELISA, WB analysis.
