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- References [21]
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- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 51073-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#51073-1-AP, RRID:AB_2197244
- Product name
- STAT6 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated STAT6 antibody (Cat. #51073-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Blockade of C5a receptor unleashes tumor-associated macrophage antitumor response and enhances CXCL9-dependent CD8(+) T cell activity.
Trichinella spiralis dipeptidyl peptidase 1 suppressed macrophage cytotoxicity by promoting M2 polarization via the STAT6/PPARγ pathway.
Macrophage autophagy deficiency-induced CEBPB accumulation alleviates atopic dermatitis via impairing M2 polarization.
Knockdown of Brg1 reduced mucus secretion in HDM stimulated airway inflammation.
Tumor-secreted GRP78 induces M2 polarization of macrophages by promoting lipid catabolism.
Intestinal Epithelial STAT6 Activation Rescues the Defective Anti-Helminth Responses Caused by Ogt Deletion.
Schisandra chinensis Lignans Exert Antidepressant Effects by Promoting BV2 Microglia Polarization toward the M2 Phenotype through the Activation of the Cannabinoid Receptor Type-2-Signal Transducer and Activator of Transcription 6 Pathway.
Ciclopirox drives growth arrest and autophagic cell death through STAT3 in gastric cancer cells.
Activation of STAT6 by intranasal allergens correlated with the development of eosinophilic chronic rhinosinusitis in a mouse model.
miR-182 targeting reprograms tumor-associated macrophages and limits breast cancer progression.
Determination of WWOX Function in Modulating Cellular Pathways Activated by AP-2α and AP-2γ Transcription Factors in Bladder Cancer.
A miR-129-5P/ARID3A Negative Feedback Loop Modulates Diffuse Large B Cell Lymphoma Progression and Immune Evasion Through Regulating the PD-1/PD-L1 Checkpoint.
Long non-coding RNA nuclear paraspeckle assembly transcript 1 promotes activation of T helper 2 cells via inhibiting STAT6 ubiquitination.
Berberine regulates macrophage polarization through IL-4-STAT6 signaling pathway in Helicobacter pylori-induced chronic atrophic gastritis.
CTHRC1 in Ovarian Cancer Promotes M2-Like Polarization of Tumor-Associated Macrophages via Regulation of the STAT6 Signaling Pathway.
IL-4 Switches Microglia/macrophage M1/M2 Polarization and Alleviates Neurological Damage by Modulating the JAK1/STAT6 Pathway Following ICH.
Ehrlichia chaffeensis Tandem Repeat Effector Targets Differentially Influence Infection.
Study on the Inhibitory Effects of Ephedra Aconite Asarum Decoction on LPS-Induced Dendritic Cells.
IRAK-M alters the polarity of macrophages to facilitate the survival of Mycobacterium tuberculosis.
Mechanism of Corilagin interference with IL-13/STAT6 signaling pathways in hepatic alternative activation macrophages in schistosomiasis-induced liver fibrosis in mouse model.
Molecular analysis of curcumin-induced polarization of murine RAW264.7 macrophages.
Luan X, Lei T, Fang J, Liu X, Fu H, Li Y, Chu W, Jiang P, Tong C, Qi H, Fu Y
Molecular therapy : the journal of the American Society of Gene Therapy 2024 Feb 7;32(2):469-489
Molecular therapy : the journal of the American Society of Gene Therapy 2024 Feb 7;32(2):469-489
Trichinella spiralis dipeptidyl peptidase 1 suppressed macrophage cytotoxicity by promoting M2 polarization via the STAT6/PPARγ pathway.
Yan SW, Zhang R, Guo X, Wang BN, Long SR, Liu RD, Wang ZQ, Cui J
Veterinary research 2023 Sep 13;54(1):77
Veterinary research 2023 Sep 13;54(1):77
Macrophage autophagy deficiency-induced CEBPB accumulation alleviates atopic dermatitis via impairing M2 polarization.
Zhu Y, Liu Y, Ma Y, Chen L, Huang H, Huang S, Zhang H, He Y, Tan C, He Y, Qiang L
Cell reports 2023 Nov 28;42(11):113430
Cell reports 2023 Nov 28;42(11):113430
Knockdown of Brg1 reduced mucus secretion in HDM stimulated airway inflammation.
Xu M, Hu J, Yang L, Gen G, Fu Z, Luo Z, Zou W
Molecular immunology 2023 Jan;153:42-50
Molecular immunology 2023 Jan;153:42-50
Tumor-secreted GRP78 induces M2 polarization of macrophages by promoting lipid catabolism.
Tian J, Zhang L, La X, Fan X, Li A, Wu C, An Y, Yan S, Dong X, Wu H, Li Z
Cellular signalling 2023 Aug;108:110719
Cellular signalling 2023 Aug;108:110719
Intestinal Epithelial STAT6 Activation Rescues the Defective Anti-Helminth Responses Caused by Ogt Deletion.
Xiong X, Huang R, Li Z, Yang C, Wang Q, Ruan HB, Xu L
International journal of molecular sciences 2022 Sep 22;23(19)
International journal of molecular sciences 2022 Sep 22;23(19)
Schisandra chinensis Lignans Exert Antidepressant Effects by Promoting BV2 Microglia Polarization toward the M2 Phenotype through the Activation of the Cannabinoid Receptor Type-2-Signal Transducer and Activator of Transcription 6 Pathway.
Wang J, Zhang G, Yang Y, Zhang X, Shi K, Zhang X, Yan T, Jia Y
Journal of agricultural and food chemistry 2022 Nov 9;70(44):14157-14169
Journal of agricultural and food chemistry 2022 Nov 9;70(44):14157-14169
Ciclopirox drives growth arrest and autophagic cell death through STAT3 in gastric cancer cells.
Chen L, Chen D, Li J, He L, Chen T, Song D, Shan S, Wang J, Lu X, Lu B
Cell death & disease 2022 Nov 28;13(11):1007
Cell death & disease 2022 Nov 28;13(11):1007
Activation of STAT6 by intranasal allergens correlated with the development of eosinophilic chronic rhinosinusitis in a mouse model.
Wei H, Xu L, Sun P, Xing H, Zhu Z, Liu J
International journal of immunopathology and pharmacology 2022 Jan-Dec;36:3946320221109529
International journal of immunopathology and pharmacology 2022 Jan-Dec;36:3946320221109529
miR-182 targeting reprograms tumor-associated macrophages and limits breast cancer progression.
Ma C, He D, Tian P, Wang Y, He Y, Wu Q, Jia Z, Zhang X, Zhang P, Ying H, Jin ZB, Hu G
Proceedings of the National Academy of Sciences of the United States of America 2022 Feb 8;119(6)
Proceedings of the National Academy of Sciences of the United States of America 2022 Feb 8;119(6)
Determination of WWOX Function in Modulating Cellular Pathways Activated by AP-2α and AP-2γ Transcription Factors in Bladder Cancer.
Kołat D, Kałuzińska Ż, Bednarek AK, Płuciennik E
Cells 2022 Apr 19;11(9)
Cells 2022 Apr 19;11(9)
A miR-129-5P/ARID3A Negative Feedback Loop Modulates Diffuse Large B Cell Lymphoma Progression and Immune Evasion Through Regulating the PD-1/PD-L1 Checkpoint.
Zheng W, Lai G, Lin Q, Issah MA, Fu H, Shen J
Frontiers in cell and developmental biology 2021;9:735855
Frontiers in cell and developmental biology 2021;9:735855
Long non-coding RNA nuclear paraspeckle assembly transcript 1 promotes activation of T helper 2 cells via inhibiting STAT6 ubiquitination.
Huang S, Dong D, Zhang Y, Chen Z, Geng J, Zhao Y
Human cell 2021 May;34(3):800-807
Human cell 2021 May;34(3):800-807
Berberine regulates macrophage polarization through IL-4-STAT6 signaling pathway in Helicobacter pylori-induced chronic atrophic gastritis.
Yang T, Wang R, Liu H, Wang L, Li J, Wu S, Chen X, Yang X, Zhao Y
Life sciences 2021 Feb 1;266:118903
Life sciences 2021 Feb 1;266:118903
CTHRC1 in Ovarian Cancer Promotes M2-Like Polarization of Tumor-Associated Macrophages via Regulation of the STAT6 Signaling Pathway.
Bai Y, Yin K, Su T, Ji F, Zhang S
OncoTargets and therapy 2020;13:5743-5753
OncoTargets and therapy 2020;13:5743-5753
IL-4 Switches Microglia/macrophage M1/M2 Polarization and Alleviates Neurological Damage by Modulating the JAK1/STAT6 Pathway Following ICH.
He Y, Gao Y, Zhang Q, Zhou G, Cao F, Yao S
Neuroscience 2020 Jun 15;437:161-171
Neuroscience 2020 Jun 15;437:161-171
Ehrlichia chaffeensis Tandem Repeat Effector Targets Differentially Influence Infection.
Luo T, Dunphy PS, McBride JW
Frontiers in cellular and infection microbiology 2017;7:178
Frontiers in cellular and infection microbiology 2017;7:178
Study on the Inhibitory Effects of Ephedra Aconite Asarum Decoction on LPS-Induced Dendritic Cells.
Ji W, Hu J, Yu X, Zhang L, Liu M, Wang Q
Evidence-based complementary and alternative medicine : eCAM 2017;2017:3272649
Evidence-based complementary and alternative medicine : eCAM 2017;2017:3272649
IRAK-M alters the polarity of macrophages to facilitate the survival of Mycobacterium tuberculosis.
Shen P, Li Q, Ma J, Tian M, Hong F, Zhai X, Li J, Huang H, Shi C
BMC microbiology 2017 Aug 23;17(1):185
BMC microbiology 2017 Aug 23;17(1):185
Mechanism of Corilagin interference with IL-13/STAT6 signaling pathways in hepatic alternative activation macrophages in schistosomiasis-induced liver fibrosis in mouse model.
Du P, Ma Q, Zhu ZD, Li G, Wang Y, Li QQ, Chen YF, Shang ZZ, Zhang J, Zhao L
European journal of pharmacology 2016 Dec 15;793:119-126
European journal of pharmacology 2016 Dec 15;793:119-126
Molecular analysis of curcumin-induced polarization of murine RAW264.7 macrophages.
Chen F, Guo N, Cao G, Zhou J, Yuan Z
Journal of cardiovascular pharmacology 2014 Jun;63(6):544-52
Journal of cardiovascular pharmacology 2014 Jun;63(6):544-52
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 51073-1-AP(STAT6 antibody) at dilution of 1:1500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human spleen using 51073-1-AP(STAT6 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The STAT6 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human STAT6. This antibody recognizes human, mouse, rat antigen. The STAT6 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
