Antibody data
- Antibody Data
- Antigen structure
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- Product number
- DPABH-07065 - Provider product page
- Provider
- Creative Diagnostics
- Proper citation
- Creative Diagnostics Cat#DPABH-07065, RRID:AB_2502804
- Product name
- Rabbit Anti-Human IRF9 Polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Interferon regulatory factor 9 (IRF9) also named Interferon-stimulated gene factor 3 gamma (ISGF3) is a transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 50 uL
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