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- Antigen structure
- References [14]
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- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 18881-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18881-1-AP, RRID:AB_10597844
- Product name
- MRPS17 antibody
- Antibody type
- Polyclonal
- Description
- MRPS17 antibody (Cat. #18881-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Identification of TMEM126A as OXA1L-interacting protein reveals cotranslational quality control in mitochondria.
Nephron progenitors rhythmically alternate between renewal and differentiation phases that synchronize with kidney branching morphogenesis.
Four-Color STED Super-Resolution RNA Fluorescent In Situ Hybridization and Immunocytochemistry to Visualize Mitochondrial mRNAs in Context with Mitochondrial Ribosomes.
Deficiency of the mitochondrial ribosomal subunit, MRPL50, causes autosomal recessive syndromic premature ovarian insufficiency.
Multi-omics identifies large mitoribosomal subunit instability caused by pathogenic MRPL39 variants as a cause of pediatric onset mitochondrial disease.
Protocol to study human mitochondrial ribosome using quantitative density gradient analysis by mass spectrometry and complexome profiling analysis.
MRPS17 promotes invasion and metastasis through PI3K/AKT signal pathway and could be potential prognostic marker for gastric cancer.
RCC1L (WBSCR16) isoforms coordinate mitochondrial ribosome assembly through their interaction with GTPases.
TRMT2B is responsible for both tRNA and rRNA m(5)U-methylation in human mitochondria.
MitoRibo-Tag Mice Provide a Tool for In Vivo Studies of Mitoribosome Composition.
METTL15 introduces N4-methylcytidine into human mitochondrial 12S rRNA and is required for mitoribosome biogenesis.
CLUH couples mitochondrial distribution to the energetic and metabolic status.
MPV17L2 is required for ribosome assembly in mitochondria.
Transcription-independent role for human mitochondrial RNA polymerase in mitochondrial ribosome biogenesis.
Poerschke S, Oeljeklaus S, Cruz-Zaragoza LD, Schenzielorz A, Dahal D, Hillen HS, Das H, Kremer LS, Valpadashi A, Breuer M, Sattmann J, Richter-Dennerlein R, Warscheid B, Dennerlein S, Rehling P
Molecular cell 2024 Jan 18;84(2):345-358.e5
Molecular cell 2024 Jan 18;84(2):345-358.e5
Nephron progenitors rhythmically alternate between renewal and differentiation phases that synchronize with kidney branching morphogenesis.
Davis SN, Grindel SH, Viola JM, Liu GY, Liu J, Qian G, Porter CM, Hughes AJ
bioRxiv : the preprint server for biology 2024 Jan 13;
bioRxiv : the preprint server for biology 2024 Jan 13;
Four-Color STED Super-Resolution RNA Fluorescent In Situ Hybridization and Immunocytochemistry to Visualize Mitochondrial mRNAs in Context with Mitochondrial Ribosomes.
Albus CA, Berlinguer-Palmini R, Chrzanowska-Lightowlers ZM, Lightowlers RN
Methods in molecular biology (Clifton, N.J.) 2023;2661:303-316
Methods in molecular biology (Clifton, N.J.) 2023;2661:303-316
Deficiency of the mitochondrial ribosomal subunit, MRPL50, causes autosomal recessive syndromic premature ovarian insufficiency.
Bakhshalizadeh S, Hock DH, Siddall NA, Kline BL, Sreenivasan R, Bell KM, Casagranda F, Kamalanathan S, Sahoo J, Narayanan N, Naik D, Suryadevara V, Compton AG, Amarasekera SSC, Kapoor R, Jaillard S, Simpson A, Robevska G, van den Bergen J, Pachernegg S, Ayers KL, Thorburn DR, Stroud DA, Hime GR, Sinclair AH, Tucker EJ
Human genetics 2023 Jul;142(7):879-907
Human genetics 2023 Jul;142(7):879-907
Multi-omics identifies large mitoribosomal subunit instability caused by pathogenic MRPL39 variants as a cause of pediatric onset mitochondrial disease.
Amarasekera SSC, Hock DH, Lake NJ, Calvo SE, Grønborg SW, Krzesinski EI, Amor DJ, Fahey MC, Simons C, Wibrand F, Mootha VK, Lek M, Lunke S, Stark Z, Østergaard E, Christodoulou J, Thorburn DR, Stroud DA, Compton AG
Human molecular genetics 2023 Jul 20;32(15):2441-2454
Human molecular genetics 2023 Jul 20;32(15):2441-2454
Protocol to study human mitochondrial ribosome using quantitative density gradient analysis by mass spectrometry and complexome profiling analysis.
Páleníková P, Minczuk M, Rebelo-Guiomar P
STAR protocols 2023 Dec 15;4(4):102605
STAR protocols 2023 Dec 15;4(4):102605
MRPS17 promotes invasion and metastasis through PI3K/AKT signal pathway and could be potential prognostic marker for gastric cancer.
Zhou W, Ouyang J, Li J, Liu F, An T, Cheng L, Kuo ZC, Zhang C, He Y
Journal of Cancer 2021;12(16):4849-4861
Journal of Cancer 2021;12(16):4849-4861
RCC1L (WBSCR16) isoforms coordinate mitochondrial ribosome assembly through their interaction with GTPases.
Reyes A, Favia P, Vidoni S, Petruzzella V, Zeviani M
PLoS genetics 2020 Jul;16(7):e1008923
PLoS genetics 2020 Jul;16(7):e1008923
TRMT2B is responsible for both tRNA and rRNA m(5)U-methylation in human mitochondria.
Powell CA, Minczuk M
RNA biology 2020 Apr;17(4):451-462
RNA biology 2020 Apr;17(4):451-462
MitoRibo-Tag Mice Provide a Tool for In Vivo Studies of Mitoribosome Composition.
Busch JD, Cipullo M, Atanassov I, Bratic A, Silva Ramos E, Schöndorf T, Li X, Pearce SF, Milenkovic D, Rorbach J, Larsson NG
Cell reports 2019 Nov 5;29(6):1728-1738.e9
Cell reports 2019 Nov 5;29(6):1728-1738.e9
METTL15 introduces N4-methylcytidine into human mitochondrial 12S rRNA and is required for mitoribosome biogenesis.
Van Haute L, Hendrick AG, D'Souza AR, Powell CA, Rebelo-Guiomar P, Harbour ME, Ding S, Fearnley IM, Andrews B, Minczuk M
Nucleic acids research 2019 Nov 4;47(19):10267-10281
Nucleic acids research 2019 Nov 4;47(19):10267-10281
CLUH couples mitochondrial distribution to the energetic and metabolic status.
Wakim J, Goudenege D, Perrot R, Gueguen N, Desquiret-Dumas V, Chao de la Barca JM, Dalla Rosa I, Manero F, Le Mao M, Chupin S, Chevrollier A, Procaccio V, Bonneau D, Logan DC, Reynier P, Lenaers G, Khiati S
Journal of cell science 2017 Jun 1;130(11):1940-1951
Journal of cell science 2017 Jun 1;130(11):1940-1951
MPV17L2 is required for ribosome assembly in mitochondria.
Dalla Rosa I, Durigon R, Pearce SF, Rorbach J, Hirst EM, Vidoni S, Reyes A, Brea-Calvo G, Minczuk M, Woellhaf MW, Herrmann JM, Huynen MA, Holt IJ, Spinazzola A
Nucleic acids research 2014 Jul;42(13):8500-15
Nucleic acids research 2014 Jul;42(13):8500-15
Transcription-independent role for human mitochondrial RNA polymerase in mitochondrial ribosome biogenesis.
Surovtseva YV, Shadel GS
Nucleic acids research 2013 Feb 1;41(4):2479-88
Nucleic acids research 2013 Feb 1;41(4):2479-88
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 18881-1-AP(MRPS17 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 18881-1-AP(MRPS17 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MRPS17 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human MRPS17. This antibody recognizes human, mouse, rat antigen. The MRPS17 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
