60342-1-Ig

antibody from Proteintech Group

Targeting: APP AD1

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

60342-1-Ig

Provider

Proteintech Group

Product name

APP antibody

Antibody type

Monoclonal

Description

APP antibody (Cat. #60342-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, pig, rat and has been validated for the following applications: IHC, WB, ELISA.

Reactivity

Human, Rat, Porcine

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

5C2A1

Vial size

20ul, 150ul

References

Submitted references

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Liu T, Chen D, Liu F, Sun Y
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Combined with network pharmacology, the therapeutic effect and mechanism of coumarins from Chimonanthus praecox extract in the treatment of Alzheimer's disease were investigated.

Zhu S, Li Y, Lin C, Liu X, Luo Y, Qian H, Tang Z
Naunyn-Schmiedeberg's archives of pharmacology 2026 Apr 13;

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Regulation of tau protein by circCwc27: shared pathogenic mechanisms in type 2 diabetes mellitus and Alzheimer's disease.

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A new protocol for the development of organoids based on molecular mechanisms in the developing newborn rat brain: Prospective applications in the study of Alzheimer's disease.

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Neuroprotective, Antioxidant and Anti-Inflammatory Effect of Greek Pomegranate Seed Oil on N2a Neuroblastoma Cells and Mild Cognitive Impairment Patients.

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Lancao decoction alleviates Alzheimer's disease: Depending on activating CaMKII to protect neuronal refunction by reducing β-amyloid in the hippocampus.

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Acromegalic Rat Model Presented Cognitive Impairments and Tau Hyperphosphorylation in the Hippocampus.

Chen J, Xiang Z, Zhang Z, Yang Y, Shu K, Lei T
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Penthorum chinense Pursh inhibits ferroptosis in cellular and Caenorhabditis elegans models of Alzheimer's disease.

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Upregulation of neuronal ER-phagy improves organismal fitness and alleviates APP toxicity.

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Chicoric Acid Ameliorated Beta-Amyloid Pathology and Enhanced Expression of Synaptic-Function-Related Markers via L1CAM in Alzheimer's Disease Models.

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Amyloid-β exposed astrocytes induce iron transport from endothelial cells at the blood-brain barrier by altering the ratio of apo- and holo-transferrin.

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Chk1 Inhibition Ameliorates Alzheimer's Disease Pathogenesis and Cognitive Dysfunction Through CIP2A/PP2A Signaling.

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Agomelatine Prevents Amyloid Plaque Deposition, Tau Phosphorylation, and Neuroinflammation in APP/PS1 Mice.

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Frontiers in aging neuroscience 2021;13:766410

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Sarsasapogenin attenuates Alzheimer-like encephalopathy in diabetes.

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Metformin activates chaperone-mediated autophagy and improves disease pathologies in an Alzheimer disease mouse model.

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CIP2A Causes Tau/APP Phosphorylation, Synaptopathy, and Memory Deficits in Alzheimer's Disease.

Shentu YP, Huo Y, Feng XL, Gilbert J, Zhang Q, Liuyang ZY, Wang XL, Wang G, Zhou H, Wang XC, Wang JZ, Lu YM, Westermarck J, Man HY, Liu R
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Sudden unexpected death in early Parkinson's disease: neurogenic or cardiac death?

Nishida N, Yoshida K, Hata Y
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