60342-1-Ig

antibody from Proteintech Group

Targeting: APP AD1

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

60342-1-Ig

Provider

Proteintech Group

Product name

APP antibody

Antibody type

Monoclonal

Description

APP antibody (Cat. #60342-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, pig, rat and has been validated for the following applications: IHC, WB, ELISA.

Reactivity

Human, Rat, Porcine

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

5C2A1

Vial size

20ul, 150ul

References

Submitted references

Penthorum chinense Pursh inhibits ferroptosis in cellular and Caenorhabditis elegans models of Alzheimer's disease.

Yong YY, Yan L, Wang BD, Fan DS, Guo MS, Yu L, Wu JM, Qin DL, Law BY, Wong VK, Yu CL, Zhou XG, Wu AG
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 May;127:155463

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Upregulation of neuronal ER-phagy improves organismal fitness and alleviates APP toxicity.

Mou W, Tang Y, Huang Y, Wu Z, Cui Y
Cell reports 2024 May 28;43(5):114255

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Chicoric Acid Ameliorated Beta-Amyloid Pathology and Enhanced Expression of Synaptic-Function-Related Markers via L1CAM in Alzheimer's Disease Models.

Wang R, Kang S, Zhao Z, Jin L, Cui X, Chen L, Schachner M, Li S, Guo Y, Zhao J
International journal of molecular sciences 2024 Mar 17;25(6)

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Agomirs upregulating carboxypeptidase E expression rescue hippocampal neurogenesis and memory deficits in Alzheimer's disease.

Jiang D, Liu H, Li T, Zhao S, Yang K, Yao F, Zhou B, Feng H, Wang S, Shen J, Tang J, Zhang YX, Wang Y, Guo C, Tang TS
Translational neurodegeneration 2024 Apr 26;13(1):24

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Apelin-13 Improves Cognitive Impairment and Repairs Hippocampal Neuronal Damage by Activating PGC-1α/PPARγ Signaling.

Chen B, Wu J, Hu S, Liu Q, Yang H, You Y
Neurochemical research 2023 May;48(5):1504-1515

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Amyloid-β exposed astrocytes induce iron transport from endothelial cells at the blood-brain barrier by altering the ratio of apo- and holo-transferrin.

Baringer SL, Lukacher AS, Palsa K, Kim H, Lippmann ES, Spiegelman VS, Simpson IA, Connor JR
bioRxiv : the preprint server for biology 2023 May 17;

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Early activation of Toll-like receptor-3 reduces the pathological progression of Alzheimer's disease in APP/PS1 mouse.

Wang S, Zhu T, Ni W, Zhou C, Zhou H, Lin L, Hu Y, Sun X, Han J, Zhou Y, Jin G, Zu J, Shi H, Yang X, Zhang Z, Hua F
Alzheimer's research & therapy 2023 Feb 16;15(1):33

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Bone Marrow-Derived GCA(+) Immune Cells Drive Alzheimer's Disease Progression.

Zhou R, Wang L, Chen L, Feng X, Zhou R, Xiang P, Wen J, Huang Y, Zhou H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(36):e2303402

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Treatment Combining Focused Ultrasound with Gastrodin Alleviates Memory Deficit and Neuropathology in an Alzheimer's Disease-Like Experimental Mouse Model.

Luo K, Wang Y, Chen WS, Feng X, Liao Y, Chen S, Liu Y, Liao C, Chen M, Ao L
Neural plasticity 2022;2022:5241449

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Gamma frequency light flicker regulates amyloid precursor protein trafficking for reducing β-amyloid load in Alzheimer's disease model.

Shen Q, Wu X, Zhang Z, Zhang D, Yang S, Xing D
Aging cell 2022 Mar;21(3):e13573

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Chk1 Inhibition Ameliorates Alzheimer's Disease Pathogenesis and Cognitive Dysfunction Through CIP2A/PP2A Signaling.

Hu W, Wang Z, Zhang H, Mahaman YAR, Huang F, Meng D, Zhou Y, Wang S, Jiang N, Xiong J, Westermarck J, Lu Y, Wang J, Wang X, Shentu Y, Liu R
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2022 Mar;19(2):570-591

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Agomelatine Prevents Amyloid Plaque Deposition, Tau Phosphorylation, and Neuroinflammation in APP/PS1 Mice.

Yang XB, Zu HB, Zhao YF, Yao K
Frontiers in aging neuroscience 2021;13:766410

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Sarsasapogenin attenuates Alzheimer-like encephalopathy in diabetes.

Zhang YM, Zheng T, Huang TT, Gu PP, Gou LS, Ma TF, Liu YW
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Oct;91:153686

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Metformin activates chaperone-mediated autophagy and improves disease pathologies in an Alzheimer disease mouse model.

Xu X, Sun Y, Cen X, Shan B, Zhao Q, Xie T, Wang Z, Hou T, Xue Y, Zhang M, Peng D, Sun Q, Yi C, Najafov A, Xia H
Protein & cell 2021 Oct;12(10):769-787

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Genomic deletion of TLR2 induces aggravated white matter damage and deteriorated neurobehavioral functions in mouse models of Alzheimer's disease.

Zhou C, Sun X, Hu Y, Song J, Dong S, Kong D, Wang Y, Hua X, Han J, Zhou Y, Jin G, Yang X, Shi H, Zhang Z, Hua F
Aging 2019 Sep 11;11(17):7257-7273

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CIP2A Causes Tau/APP Phosphorylation, Synaptopathy, and Memory Deficits in Alzheimer's Disease.

Shentu YP, Huo Y, Feng XL, Gilbert J, Zhang Q, Liuyang ZY, Wang XL, Wang G, Zhou H, Wang XC, Wang JZ, Lu YM, Westermarck J, Man HY, Liu R
Cell reports 2018 Jul 17;24(3):713-723

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Sudden unexpected death in early Parkinson's disease: neurogenic or cardiac death?

Nishida N, Yoshida K, Hata Y
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 2017 Sep-Oct;30:19-22