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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [1]
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- Product number
- AF1168 - Provider product page
- Provider
- R&D Systems
- Product name
- Human APP/Protease Nexin II Pan Specific Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Detects human APP695+1 and human APP770 in direct ELISAs and Western blots. This antibody recognizes a common epitope present on APP695+1 and APP770 found within the segments Leu18 - Arg288 or Pro365 - Arg411 of APP770 (Accession P05067).
- Reactivity
- Human
- Host
- Goat
- Conjugate
- Unconjugated
- Antigen sequence
NP_958817- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references A small molecule ApoE4-targeted therapeutic candidate that normalizes sirtuin 1 levels and improves cognition in an Alzheimer's disease mouse model.
Campagna J, Spilman P, Jagodzinska B, Bai D, Hatami A, Zhu C, Bilousova T, Jun M, Elias CJ, Pham J, Cole G, LaDu MJ, Jung ME, Bredesen DE, John V
Scientific reports 2018 Dec 4;8(1):17574
Scientific reports 2018 Dec 4;8(1):17574
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