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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [14]
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- Product number
- 66437-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- Syntaxin 1A / Syntaxin 1B antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated Syntaxin 1A / Syntaxin 1B antibody (Cat. #66437-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 2D3B5
- Vial size
- 20ul, 150ul
Submitted references Compromised synaptic signal from prefrontal cortex to mediodorsal thalamus in Alzheimer's disease models and its rescue by kinase inhibitors.
Munc18 modulates syntaxin phase separation to promote exocytosis.
Opioids induce constipation by prompting alpha-Synuclein hyperphosphorylation in the colonic myenteric plexus.
MicroRNA-502-3p modulates the GABA A subunits, synaptic proteins and mitochondrial morphology in hippocampal neurons.
Protocol for single-molecule analysis of synaptic protein complex-mediated vesicle recruitment.
Longitudinal characterization of behavioral, morphological and transcriptomic changes in a tauopathy mouse model.
Heterozygous disruption of beclin 1 alleviates neurotoxicity induced by sub-chronic exposure of arsenite in mice.
Confinement induces oxidative damage and synaptic dysfunction in mice.
Fast resupply of synaptic vesicles requires synaptotagmin-3.
Transient neuroinflammation following surgery contributes to long-lasting cognitive decline in elderly rats via dysfunction of synaptic NMDA receptor.
Transcriptomic analysis of human brains with Alzheimer's disease reveals the altered expression of synaptic genes linked to cognitive deficits.
Chronic hepatitis C virus infection impairs insulin secretion by regulation of p38δ MAPK-dependent exocytosis in pancreatic β-cells.
Munc18 and Munc13 serve as a functional template to orchestrate neuronal SNARE complex assembly.
Identification of genes associated with cortical malformation using a transposon-mediated somatic mutagenesis screen in mice.
Zhong P, Shaker T, Li P, Yan Z
The Journal of physiology 2026 Mar;604(5):2176-2190
The Journal of physiology 2026 Mar;604(5):2176-2190
Munc18 modulates syntaxin phase separation to promote exocytosis.
Pei Q, Chen Q, Tian Z, Zhu L, Chen Y, Gong J, Wang S, Xiang Y, Khamo JS, Fan J, Rong Y, Yu Y, Qin Y, Wu S, Faragalla Y, Cao P, Zhang K, Lai Y, Wu LG, Ma C, Yang X, Diao J
Nature neuroscience 2026 Feb;29(2):306-314
Nature neuroscience 2026 Feb;29(2):306-314
Opioids induce constipation by prompting alpha-Synuclein hyperphosphorylation in the colonic myenteric plexus.
Jia B, Zhao Y, Ren X, Zhang D, Jia H, Wang D, Wang L, Li J
Neurochemistry international 2025 Nov;190:106036
Neurochemistry international 2025 Nov;190:106036
MicroRNA-502-3p modulates the GABA A subunits, synaptic proteins and mitochondrial morphology in hippocampal neurons.
Sharma B, Rodarte D, Goyal G, Rodriguez S, Kumar S
bioRxiv : the preprint server for biology 2025 Jan 13;
bioRxiv : the preprint server for biology 2025 Jan 13;
Protocol for single-molecule analysis of synaptic protein complex-mediated vesicle recruitment.
Kapadia A, Hafner AS
STAR protocols 2025 Dec 19;6(4):104249
STAR protocols 2025 Dec 19;6(4):104249
Longitudinal characterization of behavioral, morphological and transcriptomic changes in a tauopathy mouse model.
Cao Q, Kumar M, Frazier A, Williams JB, Zhao S, Yan Z
Aging 2023 Nov 3;15(21):11697-11719
Aging 2023 Nov 3;15(21):11697-11719
Heterozygous disruption of beclin 1 alleviates neurotoxicity induced by sub-chronic exposure of arsenite in mice.
Li D, Qin Q, Xia Y, Cheng S, Zhang J, Duan X, Qin X, Tian X, Mao L, Qiu J, Jiang X, Zou Z, Chen C
Neurotoxicology 2023 Jan;94:11-23
Neurotoxicology 2023 Jan;94:11-23
Confinement induces oxidative damage and synaptic dysfunction in mice.
Li N, Wang H, Xin S, Min R, Zhang Y, Deng Y
Frontiers in physiology 2022;13:999574
Frontiers in physiology 2022;13:999574
Fast resupply of synaptic vesicles requires synaptotagmin-3.
Weingarten DJ, Shrestha A, Juda-Nelson K, Kissiwaa SA, Spruston E, Jackman SL
Nature 2022 Nov;611(7935):320-325
Nature 2022 Nov;611(7935):320-325
Transient neuroinflammation following surgery contributes to long-lasting cognitive decline in elderly rats via dysfunction of synaptic NMDA receptor.
Chen B, Qin G, Xiao J, Deng X, Lin A, Liu H
Journal of neuroinflammation 2022 Jul 13;19(1):181
Journal of neuroinflammation 2022 Jul 13;19(1):181
Transcriptomic analysis of human brains with Alzheimer's disease reveals the altered expression of synaptic genes linked to cognitive deficits.
Williams JB, Cao Q, Yan Z
Brain communications 2021;3(3):fcab123
Brain communications 2021;3(3):fcab123
Chronic hepatitis C virus infection impairs insulin secretion by regulation of p38δ MAPK-dependent exocytosis in pancreatic β-cells.
Chen J, Wang F, Zhou Y, Jiang J, Ksimu S, Zhang X, Li JZ, Niu J, Wang Q
Clinical science (London, England : 1979) 2020 Mar 13;134(5):529-542
Clinical science (London, England : 1979) 2020 Mar 13;134(5):529-542
Munc18 and Munc13 serve as a functional template to orchestrate neuronal SNARE complex assembly.
Wang S, Li Y, Gong J, Ye S, Yang X, Zhang R, Ma C
Nature communications 2019 Jan 8;10(1):69
Nature communications 2019 Jan 8;10(1):69
Identification of genes associated with cortical malformation using a transposon-mediated somatic mutagenesis screen in mice.
Lu IL, Chen C, Tung CY, Chen HH, Pan JP, Chang CH, Cheng JS, Chen YA, Wang CH, Huang CW, Kang YN, Chang HY, Li LL, Chang KP, Shih YH, Lin CH, Kwan SY, Tsai JW
Nature communications 2018 Jun 27;9(1):2498
Nature communications 2018 Jun 27;9(1):2498
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