Antibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 11713-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11713-1-AP, RRID:AB_10637266
- Product name
- DNAJA1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated DNAJA1 antibody (Cat. #11713-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references DNAJA1‑knockout alleviates heat stroke‑induced endothelial barrier disruption via improving thermal tolerance and suppressing the MLCK‑MLC signaling pathway.
DNAJA1 positively regulates amino acid-stimulated milk protein and fat synthesis in bovine mammary epithelial cells.
A curcumin analogue GO-Y030 depletes cancer stem cells by inhibiting the interaction between the HSP70/HSP40 complex and its substrates.
A cytosolic surveillance mechanism activates the mitochondrial UPR.
Heat-shock chaperone HSPB1 regulates cytoplasmic TDP-43 phase separation and liquid-to-gel transition.
Inhibition of the CDK2 and Cyclin A complex leads to autophagic degradation of CDK2 in cancer cells.
Mutant p53 Depletion by Novel Inhibitors for HSP40/J-Domain Proteins Derived from the Natural Compound Plumbagin.
Cul4A-DDB1-mediated monoubiquitination of phosphoglycerate dehydrogenase promotes colorectal cancer metastasis via increased S-adenosylmethionine.
Age-associated changes in microglia and astrocytes ameliorate blood-brain barrier dysfunction.
Co-chaperones DNAJA1 and DNAJB6 are critical for regulation of polyglutamine aggregation.
A cytosolic chaperone complex controls folding and degradation of type III CD38.
DjA1 maintains Golgi integrity via interaction with GRASP65.
Li L, Wang YW, Chang X, Chen JL, Wang M, Zhu JQ, Li JF, Ren LJ, Dai XY, Yan L, Fan XC, Song Q, Zhu JB, Chen JK, Xu SG
Molecular medicine reports 2024 May;29(5)
Molecular medicine reports 2024 May;29(5)
DNAJA1 positively regulates amino acid-stimulated milk protein and fat synthesis in bovine mammary epithelial cells.
Li Z, Yuan X, Wang Y, Sun Z, Ao J
Cell biochemistry and function 2024 Jan;42(1):e3918
Cell biochemistry and function 2024 Jan;42(1):e3918
A curcumin analogue GO-Y030 depletes cancer stem cells by inhibiting the interaction between the HSP70/HSP40 complex and its substrates.
Suzuki M, Yamamoto Y, Nishijima-Matsunobu A, Kawasaki Y, Shibata H, Omori Y
FEBS open bio 2023 Mar;13(3):434-446
FEBS open bio 2023 Mar;13(3):434-446
A cytosolic surveillance mechanism activates the mitochondrial UPR.
Sutandy FXR, Gößner I, Tascher G, Münch C
Nature 2023 Jun;618(7966):849-854
Nature 2023 Jun;618(7966):849-854
Heat-shock chaperone HSPB1 regulates cytoplasmic TDP-43 phase separation and liquid-to-gel transition.
Lu S, Hu J, Arogundade OA, Goginashvili A, Vazquez-Sanchez S, Diedrich JK, Gu J, Blum J, Oung S, Ye Q, Yu H, Ravits J, Liu C, Yates JR 3rd, Cleveland DW
Nature cell biology 2022 Sep;24(9):1378-1393
Nature cell biology 2022 Sep;24(9):1378-1393
Inhibition of the CDK2 and Cyclin A complex leads to autophagic degradation of CDK2 in cancer cells.
Zhang J, Gan Y, Li H, Yin J, He X, Lin L, Xu S, Fang Z, Kim BW, Gao L, Ding L, Zhang E, Ma X, Li J, Li L, Xu Y, Horne D, Xu R, Yu H, Gu Y, Huang W
Nature communications 2022 May 20;13(1):2835
Nature communications 2022 May 20;13(1):2835
Mutant p53 Depletion by Novel Inhibitors for HSP40/J-Domain Proteins Derived from the Natural Compound Plumbagin.
Alalem M, Bhosale M, Ranjan A, Yamamoto S, Kaida A, Nishikawa S, Parrales A, Farooki S, Anant S, Padhye S, Iwakuma T
Cancers 2022 Aug 29;14(17)
Cancers 2022 Aug 29;14(17)
Cul4A-DDB1-mediated monoubiquitination of phosphoglycerate dehydrogenase promotes colorectal cancer metastasis via increased S-adenosylmethionine.
Zhang Y, Yu H, Zhang J, Gao H, Wang S, Li S, Wei P, Liang J, Yu G, Wang X, Li X, Li D, Yang W
The Journal of clinical investigation 2021 Nov 1;131(21)
The Journal of clinical investigation 2021 Nov 1;131(21)
Age-associated changes in microglia and astrocytes ameliorate blood-brain barrier dysfunction.
Pan J, Ma N, Zhong J, Yu B, Wan J, Zhang W
Molecular therapy. Nucleic acids 2021 Dec 3;26:970-986
Molecular therapy. Nucleic acids 2021 Dec 3;26:970-986
Co-chaperones DNAJA1 and DNAJB6 are critical for regulation of polyglutamine aggregation.
Rodríguez-González C, Lin S, Arkan S, Hansen C
Scientific reports 2020 May 18;10(1):8130
Scientific reports 2020 May 18;10(1):8130
A cytosolic chaperone complex controls folding and degradation of type III CD38.
Wu Y, Zhang J, Fang L, Lee HC, Zhao YJ
The Journal of biological chemistry 2019 Mar 15;294(11):4247-4258
The Journal of biological chemistry 2019 Mar 15;294(11):4247-4258
DjA1 maintains Golgi integrity via interaction with GRASP65.
Li J, Tang D, Ireland SC, Wang Y
Molecular biology of the cell 2019 Feb 15;30(4):478-490
Molecular biology of the cell 2019 Feb 15;30(4):478-490
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse lung tissue were subjected to SDS PAGE followed by western blot with 11713-1-AP(DNAJA1 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The DNAJA1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human DNAJA1. This antibody recognizes human, mouse antigen. The DNAJA1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.