67882-1-Ig

antibody from Proteintech Group

Targeting: LPCAT3 C3F, MBOAT5, nessy, OACT5

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

67882-1-Ig

Provider

Proteintech Group

Product name

LPCAT3 antibody

Antibody type

Monoclonal

Description

LPCAT3 antibody (Cat. #67882-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, mouse, pig and has been validated for the following applications: IHC, WB, ELISA.

Reactivity

Human, Mouse, Porcine

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

1C1G3

Vial size

20ul, 150ul

References

Submitted references

β-Hydroxybutyrate-Induced Ferroptosis Contributes to Hepatic Oxidative Injury in Dairy Cows with Clinical Ketosis.

Mei S, Wang L, Ding Y, Wang H, Yang Y, Li C, Liu G, Du X, Fang Z
Journal of agricultural and food chemistry 2026 Jan 14;74(1):807-819

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Modulation of Macrophage ferroptosis under the guide of infrared thermography promotes the healing of pressure injuries.

Jiang X, Zhang X, Deng H, Lin L, Wang Y, Wang Y, Huang J, Yang N, Xu S, Wang J, Shi K, Tao K, Chen Z, Cai F, Zhou K, Xiao J
Journal of advanced research 2026 Feb;80:265-285

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Application of a novel myristoylproteomics approach identifies GLIPR2 as a key pro-ferroptotic substrate in non-small cell lung cancer.

Wang Y, Guo S, Guo W, Tian X, Miao Y, Qiu S, Xue X, Wang Y, Cui J, Xu X, Wang J, Zhang X
Materials today. Bio 2026 Apr;37:102945

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Mechanistic study on electroacupuncture-regulated circadian autophagy for inhibiting ferroptosis in hippocampal neurons and alleviating depression-like behaviors in adulthood induced by early chronic sleep deprivation.

Wu Y, Chen X, Liu F, Feng Y, Liao Z, Bu X, Fu W, Gao J, Wu L, Fan L, Yang Q, Yue P, Wang M
Frontiers in neurology 2025;16:1680606

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Polydatin Alleviated Ischemia-Reperfusion Induced Kidney Injury by Inhibiting SETD2-Mediated Ferroptosis.

He M, Tang S, Wang L, Hu X, Yao X, Wu H
Phytotherapy research : PTR 2025 Nov;39(11):5391-5408

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Rosmarinic acid induces ferroptosis in colon cancer: insights from AKR1C3/PTGS2 pathway and mitochondrial dysfunction.

Tang J, Zhang J, Chen H, Wang Z, Wu L, Xue P, Yang R, Peng W, Zeng P
3 Biotech 2025 Nov;15(11):374

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Exercise-induced weight loss modulates brain iron and omega-3 fatty acid metabolism in middle-aged obese rats.

Lin WL, Chang CC, Chen SH, Faradina A, Chiu WC, Huang SY, Tung TH, Tseng SH, Skalny AV, Tinkov AA, Aschner M, Chang JS
Nutrition (Burbank, Los Angeles County, Calif.) 2025 Nov;139:112872

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Arachidonic acid induces ferroptosis in hepatocellular carcinoma via the SIRT5-ACSL4/LPCAT3/ALOX15 axis, leading to lipid peroxidation and mitochondrial dysfunction.

Xue P, Zhang J, Wang Z, Wu L, Tang J, Yang R, Gao W, Zeng P
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157450

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Unravelling lumbar disc herniation severity beyond MRI : integrated transcriptomic and metabolomic analyses highlight glycerophospholipid metabolism and inform a machine-learning diagnostic model: a pilot study.

Deng Q, Ren S, Zhang N, Li G, Yu Z, Li X, Cui H, Zhang Y, Zhang Y, Chen J
Bone & joint research 2025 May 12;14(5):434-447

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Deuterium-reinforced polyunsaturated fatty acids protect against muscle atrophy by STZ-induced diabetic mice.

Eshima H, Ishihara T, Tabuchi A, Kano Y, Kurokawa K, Shchepinov MS
Free radical biology & medicine 2025 Mar 16;230:273-282

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Chlorogenic acid induces hepatocellular carcinoma cell ferroptosis via PTGS2/AKR1C3/GPX4 axis-mediated reprogramming of arachidonic acid metabolism.

Wu L, Chen HY, Zhang JT, Yang RY, Wang ZB, Xue PS, Peng W, Li KX, Gao WH, Zeng PH
World journal of gastrointestinal oncology 2025 Mar 15;17(3):98844

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Ginsenoside RK1 Promotes Hepatic Stellate Cell Glycolysis-Mediated Ferroptosis by Activating the HK2/ACSL4/LPCAT3/ALOX5 Signaling Pathway.

Xia Z, Wang Y, Zhao Q, Deng M, Li C, Zeng Y, Xu J, Ying H, Zhu D, Zhang X, Wu X, Cai W, Zhou R, Yu F
Journal of agricultural and food chemistry 2025 Jul 9;73(27):17205-17218

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Gastrodin: Modulating the xCT/GPX4 and ACSL4/LPCAT3 pathways to inhibit ferroptosis after ischemic stroke.

Gong C, Fu X, Ma Q, He M, Zhu X, Liu L, Zhou D, Yan S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156331

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Unlocking the potential of Traditional Chinese Medicine (TCM): Shipi Xiaoji formula (SPXJF) as a novel ferroptosis inducer in hepatocellular carcinoma.

Yang R, Fu X, Wang Z, Xue P, Wu L, Tan X, Peng W, Li K, Gao W, Zeng P
Journal of ethnopharmacology 2025 Jan 31;340:119236

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Ferrostatin-1 inhibits osteoclast differentiation and prevents osteoporosis by suppressing lipid peroxidation.

Xu W, Lv S, Wang X, Song C, Xi C, Yan J
Journal of orthopaedic surgery and research 2025 Jan 30;20(1):117

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A pH responsive nanocomposite for combination sonodynamic-immunotherapy with ferroptosis and calcium ion overload via SLC7A11/ACSL4/LPCAT3 pathway.

Bai X, Kang J, Wei S, Wang Y, Liu Y, Yuan B, Lu Q, Li H, Yan J, Yang X, Chang J
Exploration (Beijing, China) 2025 Feb;5(1):20240002

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Leukemia-expanded splenic CD81+ erythroblasts potentiate disease progression in mice by reshaping leukemic cell metabolism.

Li Y, Cao J, Tong J, Tang P, Chen H, Sun G, Yang Z, Zhang X, Dong F, Yang S, Gao J, Zhao X, Ma J, Wang D, Zhang L, Wang L, Cheng T, Cheng H, Shi L
The Journal of clinical investigation 2025 Dec 15;135(24)

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Remodeling adipocytes' lipid metabolism with a polycation loaded enzyme-active framework reverses osteoporotic bone marrow.

Lin W, Gu S, Zhang X, Li K, Zhao D, Ma B, Pan C, Xu Z, Liu T, Wang H, Hu S, Chen H
Nature communications 2025 Aug 27;16(1):8009

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Targeting lipid scrambling potentiates ferroptosis and triggers tumor immune rejection.

Yang M, Yu Z, Ping J, Duan Y, Tang J, Liu W, He Q, Lai Y, Lam SM, Tang H, Liu Z, Wang W, Zhu M, Hu W, Han Y, Shui G, Hao J, Liu Z, Wu N
Science advances 2025 Aug 15;11(33):eadx6587

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Role of ferroptosis mediated by abnormal membrane structure in DEHP-induced reproductive injury.

Deng W, Zhao J, Wang X, Li D, Wang M, Zheng X, Wang R, Guo Q, Zhao P, Yan H, Shen L, Long C, Wei G, Wu S
Free radical biology & medicine 2025 Aug 1;235:150-161

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Electroacupuncture Ameliorates Chronic Inflammatory Pain and Depression Comorbidity by Inhibiting Nrf2-Mediated Ferroptosis in Hippocampal Neurons.

Liu G, Liu D, Shi D, Wang Z, Fu W
Neurochemical research 2025 Apr 21;50(3):149

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Rosmarinic acid liposomes suppress ferroptosis in ischemic brain via inhibition of TfR1 in BMECs.

Jia CL, Gou Y, Gao Y, Pei X, Jin X, Li BL, Zhang Z, He Y, Ji ES, Zhao Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155835

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Targeting Ferroptosis with Small Molecule Atranorin (ATR) as a Novel Therapeutic Strategy and Providing New Insight into the Treatment of Breast Cancer.

Ensoy M, Cansaran-Duman D
Pharmaceuticals (Basel, Switzerland) 2024 Oct 16;17(10)

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Unveiling the crucial role of ferroptosis in host resistance to streptococcus agalactiae infection.

Yi JX, Sun ZY, Liu P, Wang YH, Liu H, Lv QY, Kong DC, Huang WH, Ren YH, Li Q, Jiang YQ, Li J, Jiang H
Cell death discovery 2024 Oct 1;10(1):423

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Z-Ligustilide restricts rabies virus replication by inducing ferroptosis through the ACSL4-LPCAT3-POR pathway.

Zhao J, Wang Q, Liu Z, Sun M, Zhou R, Fu ZF, Zhao L, Zhou M
Veterinary microbiology 2024 Nov;298:110260

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Di-(2-ethylhexyl) phthalate induces ferroptosis in prepubertal mouse testes via the lipid metabolism pathway.

Wang X, Li D, Zheng X, Hong Y, Zhao J, Deng W, Wang M, Shen L, Long C, Wei G, Wu S
Environmental toxicology 2024 Mar;39(3):1747-1758

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Mefloquine enhances the efficacy of anti-PD-1 immunotherapy via IFN-γ-STAT1-IRF1-LPCAT3-induced ferroptosis in tumors.

Tao Q, Liu N, Wu J, Chen J, Chen X, Peng C
Journal for immunotherapy of cancer 2024 Mar 11;12(3)

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Gut microbiota regulates the ALK5/NOX1 axis by altering glutamine metabolism to inhibit ferroptosis of intrahepatic cholangiocarcinoma cells.

Zhang Q, Zhou J, Zhai D, Jiang Q, Yang M, Zhou M
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167152

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MaiJiTong granule attenuates atherosclerosis by reducing ferroptosis via activating STAT6-mediated inhibition of DMT1 and SOCS1/p53 pathways in LDLR(-/-) mice.

Shi J, Yang MM, Yang S, Fan F, Zheng G, Miao Y, Hua Y, Zhang J, Cheng Y, Liu S, Guo Y, Guo L, Yang X, Fan G, Ma C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155489

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Excessive SOX8 reprograms energy and iron metabolism to prime hepatocellular carcinoma for ferroptosis.

Yang X, Gu C, Cai J, Li F, He X, Luo L, Xiao W, Hu B, Hu J, Qian H, Ren S, Zhang L, Zhu X, Yang L, Yang J, Yang Z, Zheng Y, Huang X, Wang Z
Redox biology 2024 Feb;69:103002

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Investigation of Metabolic and Inflammatory Disorder in the Aging FGF21 Knockout Mouse.

Cai LQ, Li XC, Wang YY, Chen YX, Zhu XY, Zuo ZY, Si-Ma YQ, Lin YN, Li XK, Huang XY
Inflammation 2024 Dec;47(6):2173-2195

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BMAL1 alleviates sepsis-induced AKI by inhibiting ferroptosis.

Yang S, Ye Z, Chen W, Wang P, Zhao S, Zhou X, Li W, Cheng F
International immunopharmacology 2024 Dec 5;142(Pt B):113159

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A new therapeutic strategy for luminal A-breast cancer treatment: vulpinic acid as an anti-neoplastic agent induces ferroptosis and apoptosis mechanisms.

Alkan AH, Ensoy M, Cansaran-Duman D
Medical oncology (Northwood, London, England) 2024 Aug 19;41(9):229

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Crizotinib and its enantiomer suppress ferroptosis by decreasing PE-O-PUFA content.

Cen SY, Lin F, Li X, Hu Y, Liu JP, Xue Z, Gao Y, Sun YP, Zhu S, Dang Y, Zhao Y, Yuan HX
Cell death discovery 2024 Aug 12;10(1):360

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Neuroinvasive virus facilitates viral replication by employing lipid droplets to reduce arachidonic acid-induced ferroptosis.

Zhao J, Wang Q, Liu Z, Zhang M, Li J, Fu ZF, Zhao L, Zhou M
The Journal of biological chemistry 2024 Apr;300(4):107168

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Insight into the effect of a heavy metal mixture on neurological damage in rats through combined serum metabolomic and brain proteomic analyses.

Xie J, Zhou F, Ouyang L, Li Q, Rao S, Su R, Yang S, Li J, Wan X, Yan L, Liu P, Cheng H, Li L, Du G, Feng C, Fan G
The Science of the total environment 2023 Oct 15;895:165009

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The deubiquitinase ZRANB1 is an E3 ubiquitin ligase for SLC7A11 and regulates ferroptotic resistance.

Huang S, Zhang Q, Zhao M, Wang X, Zhang Y, Gan B, Zhang P
The Journal of cell biology 2023 Nov 6;222(11)

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Lipid reprogramming induced by the TFEB-ERRα axis enhanced membrane fluidity to promote EC progression.

Mao X, Lei H, Yi T, Su P, Tang S, Tong Y, Dong B, Ruan G, Mustea A, Sehouli J, Sun P
Journal of experimental & clinical cancer research : CR 2022 Jan 19;41(1):28

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Cadmium perturbed lipid profile and induced liver dysfunction in mice through phosphatidylcholine remodeling and promoting arachidonic acid synthesis and metabolism.

Gu J, Kong A, Guo C, Liu J, Li K, Ren Z, Zhou Y, Tang M, Shi H
Ecotoxicology and environmental safety 2022 Dec 1;247:114254