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- References [22]
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- Product number
- 25136-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- DAPK1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated DAPK1 antibody (Cat. #25136-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references O-GlcNAcylation of YAP1 promotes lung transplant ischemia-reperfusion injury via binding to HIF1α transcription factor and activating autophagy and mitophagy.
DAPK1 orchestrates cell division and junction to control corneal epithelial development.
DAPK1 induces motor neuron apoptosis in hSOD1(G93A)-linked amyotrophic lateral sclerosis via regulating the Xiap/JNK pathway.
Epigenetic Regulation of DAPK1 and Netrin-1 Drives Diabetic Encephalopathy.
DAPK1-positve macrophages facilitate immunosuppressive microenvironment and determine immunotherapy efficacy in colorectal cancer.
Microcystin-LR Exposure Damages Neurons by Inducing α-Syn Aggregation via MAPK4/GATA2/SNCA and PP2A/GRKs Pathways.
Epileptic seizures induced by pentylenetetrazole kindling accelerate Alzheimer-like neuropathology in 5×FAD mice.
Protection of blood-brain barrier by endothelial DAPK1 deletion after stroke.
The targeting of DAPK1 with miR-190a-3p promotes autophagy in trophoblast cells.
Self-healing hydrogels loaded with Spatholobi Caulis alleviate disc degeneration by promoting autophagy in nucelus pulposus.
Long non-coding RNA nuclear paraspeckle assembly transcript 1 downregulation protects lens epithelial cells from oxidative stress-induced apoptosis by regulating the microRNA-124-3p/death-associated protein kinase 1 axis in age-related cataract.
Auto- and paracrine rewiring of NIX-mediated mitophagy by insulin-like growth factor-binding protein 7 in septic AKI escalates inflammation-coupling tubular damage.
P38-DAPK1 axis regulated LC3-associated phagocytosis (LAP) of microglia in an in vitro subarachnoid hemorrhage model.
Sanggenon C inhibits cell proliferation and induces apoptosis by regulating the MIB1/DAPK1 axis in glioblastoma.
Yifei sanjie Pills Alleviate Chemotherapy-Related Fatigue by Reducing Skeletal Muscle Injury and Inhibiting Tumor Growth in Lung Cancer Mice.
Death-Associated Protein Kinase 1 Regulates Oxidative Stress in Cardiac Ischemia Reperfusion Injury.
Reduced DAPK1 Expression Promotes Stem Cell-Like Characteristics of Prostate Cancer Cells by Activating ZEB1 via Hippo/YAP Signaling Pathway.
Requirement of splicing factor hnRNP A2B1 for tumorigenesis of melanoma stem cells.
Oxytocin Alleviates MPTP-Induced Neurotoxicity in Mice by Targeting MicroRNA-26a/Death-Associated Protein Kinase 1 Pathway.
Comparison of the Effects of Nonprotein and Protein Nitrogen on Apoptosis and Autophagy of Rumen Epithelial Cells in Goats.
Low DAPK1 expression correlates with poor prognosis and sunitinib resistance in clear cell renal cell carcinoma.
Central Regulatory Role for SIN1 in Interferon γ (IFNγ) Signaling and Generation of Biological Responses.
Dai S, Wan X, Xia L, Xu L, Xie C, Wang G, Tang J
Cell death & disease 2026 Mar 15;17(1)
Cell death & disease 2026 Mar 15;17(1)
DAPK1 orchestrates cell division and junction to control corneal epithelial development.
Yang M, Zhao Z, Bu W, Li L, Lin X, Hu M, Dong D, Jiao L, Shan Y, Liu M, Li D
European journal of cell biology 2026 Jun;105(2):151532
European journal of cell biology 2026 Jun;105(2):151532
DAPK1 induces motor neuron apoptosis in hSOD1(G93A)-linked amyotrophic lateral sclerosis via regulating the Xiap/JNK pathway.
Su X, Tan X, Wang Y, Liang W, Wang D, Huo D, Wang H, Qi Y, Zhang W, Han L, Zhang D, Wang M, Xu J, Feng H
Molecular and cellular neurosciences 2025 Sep;134:104029
Molecular and cellular neurosciences 2025 Sep;134:104029
Epigenetic Regulation of DAPK1 and Netrin-1 Drives Diabetic Encephalopathy.
Zhou Y, Kou JX, Zheng K, Guo ZX, Fan HW, Li WL, Chu LL, Yin JW, Liu LJ, Brazhe N, Xiang ZG, Hu F, Shu K, Zhu LQ, Liu D
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(37):e02535
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(37):e02535
DAPK1-positve macrophages facilitate immunosuppressive microenvironment and determine immunotherapy efficacy in colorectal cancer.
Chang J, Niu Y, Zhou S, Zhang Z, Zhu W, Zhu J, Xiu H, Shang K, Feng Q, Wei Y
Journal of translational medicine 2025 Nov 4;23(1):1220
Journal of translational medicine 2025 Nov 4;23(1):1220
Microcystin-LR Exposure Damages Neurons by Inducing α-Syn Aggregation via MAPK4/GATA2/SNCA and PP2A/GRKs Pathways.
Yan M, Wu H, Wu T, Wang Y, Su C, Li D, Han X
Molecular neurobiology 2025 May;62(5):6195-6211
Molecular neurobiology 2025 May;62(5):6195-6211
Epileptic seizures induced by pentylenetetrazole kindling accelerate Alzheimer-like neuropathology in 5×FAD mice.
Zou Y, Wang C, Li H, Zhong M, Lin J, Hu Y, Chen Z, Gan CL
Frontiers in pharmacology 2024;15:1500105
Frontiers in pharmacology 2024;15:1500105
Protection of blood-brain barrier by endothelial DAPK1 deletion after stroke.
Gu Z, Li S, Liu J, Zhang X, Pang C, Ding L, Cao C
Biochemical and biophysical research communications 2024 Sep 10;724:150216
Biochemical and biophysical research communications 2024 Sep 10;724:150216
The targeting of DAPK1 with miR-190a-3p promotes autophagy in trophoblast cells.
Luo QQ, Tian Y, Qu GJ, Huang K, Hu PP, Xue Y, Hu BF, Luo SS
Molecular reproduction and development 2024 Jan;91(1):e23724
Molecular reproduction and development 2024 Jan;91(1):e23724
Self-healing hydrogels loaded with Spatholobi Caulis alleviate disc degeneration by promoting autophagy in nucelus pulposus.
Cai S, Ding R, Zhang H, Chen Q, Yu F, Xia Y, Chen Q, Miao X, Zhou B, Chen J, Liao L, Cheng X, Fu X
Materials today. Bio 2024 Dec;29:101323
Materials today. Bio 2024 Dec;29:101323
Long non-coding RNA nuclear paraspeckle assembly transcript 1 downregulation protects lens epithelial cells from oxidative stress-induced apoptosis by regulating the microRNA-124-3p/death-associated protein kinase 1 axis in age-related cataract.
Guo X, Li C, Wang Y, Jiang C, Yang L
International ophthalmology 2023 Sep;43(9):3413-3424
International ophthalmology 2023 Sep;43(9):3413-3424
Auto- and paracrine rewiring of NIX-mediated mitophagy by insulin-like growth factor-binding protein 7 in septic AKI escalates inflammation-coupling tubular damage.
Hu BC, Zhu JW, Wu GH, Cai JJ, Yang X, Shao ZQ, Zheng Y, Lai JM, Shen Y, Yang XH, Liu JQ, Sun RH, Zhu HP, Ye XM, Mo SJ
Life sciences 2023 Jun 1;322:121653
Life sciences 2023 Jun 1;322:121653
P38-DAPK1 axis regulated LC3-associated phagocytosis (LAP) of microglia in an in vitro subarachnoid hemorrhage model.
Chen XX, Tao T, Liu XZ, Wu W, Wang JW, Yue TT, Li XJ, Zhou Y, Gao S, Sheng B, Peng Z, Xu HJ, Ding PF, Wu LY, Zhang DD, Lu Y, Hang CH, Li W
Cell communication and signaling : CCS 2023 Jul 21;21(1):175
Cell communication and signaling : CCS 2023 Jul 21;21(1):175
Sanggenon C inhibits cell proliferation and induces apoptosis by regulating the MIB1/DAPK1 axis in glioblastoma.
Chang H, Hou J, Shao Y, Xu M, Weng X, Du Y, Shi J, Zhang L, Cui H
MedComm 2023 Aug;4(4):e281
MedComm 2023 Aug;4(4):e281
Yifei sanjie Pills Alleviate Chemotherapy-Related Fatigue by Reducing Skeletal Muscle Injury and Inhibiting Tumor Growth in Lung Cancer Mice.
Wu Y, Pi D, Chen Y, Zuo Q, Lin L, Ouyang M
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2357616
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2357616
Death-Associated Protein Kinase 1 Regulates Oxidative Stress in Cardiac Ischemia Reperfusion Injury.
Li W, Yu W, Xu W, Xiong J, Zhong X, Hu S, Yu J
Cells, tissues, organs 2021;210(5-6):380-390
Cells, tissues, organs 2021;210(5-6):380-390
Reduced DAPK1 Expression Promotes Stem Cell-Like Characteristics of Prostate Cancer Cells by Activating ZEB1 via Hippo/YAP Signaling Pathway.
Nong S, Wei Z, Wang Z, Ma L, Guan Y, Ni J
Stem cells and development 2021 Sep 15;30(18):934-945
Stem cells and development 2021 Sep 15;30(18):934-945
Requirement of splicing factor hnRNP A2B1 for tumorigenesis of melanoma stem cells.
Chu M, Wan H, Zhang X
Stem cell research & therapy 2021 Jan 28;12(1):90
Stem cell research & therapy 2021 Jan 28;12(1):90
Oxytocin Alleviates MPTP-Induced Neurotoxicity in Mice by Targeting MicroRNA-26a/Death-Associated Protein Kinase 1 Pathway.
Almansoub HAMM, Tang H, Wu Y, Wang DQ, Mahaman YAR, Salissou MTM, Lu Y, Hu F, Zhou LT, Almansob YAM, Liu D
Journal of Alzheimer's disease : JAD 2020;74(3):883-901
Journal of Alzheimer's disease : JAD 2020;74(3):883-901
Comparison of the Effects of Nonprotein and Protein Nitrogen on Apoptosis and Autophagy of Rumen Epithelial Cells in Goats.
Kong Z, Zhou C, Kang J, Tan Z
Animals : an open access journal from MDPI 2020 Nov 9;10(11)
Animals : an open access journal from MDPI 2020 Nov 9;10(11)
Low DAPK1 expression correlates with poor prognosis and sunitinib resistance in clear cell renal cell carcinoma.
Song Z, Li Z, Han W, Zhu C, Lou N, Li X, Luo G, Peng S, Li G, Zhao Y, Guo Y
Aging 2020 Nov 16;13(2):1842-1858
Aging 2020 Nov 16;13(2):1842-1858
Central Regulatory Role for SIN1 in Interferon γ (IFNγ) Signaling and Generation of Biological Responses.
Kroczynska B, Blyth GT, Rafidi RL, Majchrzak-Kita B, Xu L, Saleiro D, Kosciuczuk EM, Jemielity J, Su B, Altman JK, Eklund EA, Fish EN, Platanias LC
The Journal of biological chemistry 2017 Mar 17;292(11):4743-4752
The Journal of biological chemistry 2017 Mar 17;292(11):4743-4752
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The DAPK1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human DAPK1. This antibody recognizes human antigen. The DAPK1 antibody has been validated for the following applications: ELISA, WB analysis.
