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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [23]
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- Product number
- 66545-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- STAT1 antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated STAT1 antibody (Cat. #66545-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, rat, mouse and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1F7C6
- Vial size
- 20ul, 150ul
Submitted references IRF7 from the black flying fox induces a STAT1-independent ISG response in unstimulated cell lines that protects against diverse RNA viruses.
Verapamil and tangeretin enhances the M1 macrophages to M2 type in lipopolysaccharide-treated mice and inhibits the P-glycoprotein expression by downregulating STAT1/STAT3 and upregulating SOCS3.
Resveratrol-loaded sulfated Hericium erinaceus β-glucan-chitosan nanoparticles: Preparation, characterization and synergistic anti-inflammatory effects.
IL-21-armored B7H3 CAR-iNKT cells exert potent antitumor effects.
Endogenous blocking of TLR2 along with TNF-α and IL-1β ameliorates the severity of the S. aureus arthritis via modulating STAT3/SOCS3 expressions in tissue resident macrophages.
Persistent tailoring of MSC activation through genetic priming.
Single cell analysis reveals the roles and regulatory mechanisms of type-I interferons in Parkinson's disease.
Interferon inhibits a model RNA virus via a limited set of inducible effector genes.
IL-17 promotes melanoma through TRAF2 as a scaffold protein recruiting PIAS2 and ELAVL1 to induce EPHA5.
Silencing SIRT1 promotes the anti-HBV action of IFN-α by regulating Pol expression and activating the JAK-STAT signaling pathway.
GSTM2 alleviates heart failure by inhibiting DNA damage in cardiomyocytes.
POR overexpression induces tamoxifen-resistance in breast cancer through the STAT1/c-Myc pathway.
Retinoic Acid Prevents α-Synuclein Preformed Fibrils-Induced Toxicity via Inhibiting STAT1-PARP1 Signaling.
Free ISG15 inhibits Pseudorabies virus infection by positively regulating type I IFN signaling.
Proteome-centric cross-omics characterization and integrated network analyses of triple-negative breast cancer.
Panax notoginseng saponins prevent colitis-associated colorectal cancer via inhibition IDO1 mediated immune regulation.
Dual Inhibition of Endoplasmic Reticulum Stress and Oxidation Stress Manipulates the Polarization of Macrophages under Hypoxia to Sensitize Immunotherapy.
Comparative proteomics reveals Cryptosporidium parvum manipulation of the host cell molecular expression and immune response.
Statins attenuate antiviral IFN-β and ISG expression via inhibition of IRF3 and JAK/STAT signaling in poly(I:C)-treated hyperlipidemic mice and macrophages.
Increased expression of IFN-γ in preeclampsia impairs human trophoblast invasion via a SOCS1/JAK/STAT1 feedback loop.
Bicarbonate enhances the inflammatory response by activating JAK/STAT signalling in LPS + IFN-γ-stimulated macrophages.
Rhein attenuates renal inflammatory injury of uric acid nephropathy via lincRNA-Cox2/miR-150-5p/STAT1 axis.
E2F2 directly regulates the STAT1 and PI3K/AKT/NF-κB pathways to exacerbate the inflammatory phenotype in rheumatoid arthritis synovial fibroblasts and mouse embryonic fibroblasts.
Cruz-Rivera PC, Eitson JL, Schoggins JW
bioRxiv : the preprint server for biology 2024 May 5;
bioRxiv : the preprint server for biology 2024 May 5;
Verapamil and tangeretin enhances the M1 macrophages to M2 type in lipopolysaccharide-treated mice and inhibits the P-glycoprotein expression by downregulating STAT1/STAT3 and upregulating SOCS3.
Kundu A, Ghosh P, Bishayi B
International immunopharmacology 2024 May 30;133:112153
International immunopharmacology 2024 May 30;133:112153
Resveratrol-loaded sulfated Hericium erinaceus β-glucan-chitosan nanoparticles: Preparation, characterization and synergistic anti-inflammatory effects.
Zhang Z, Ge M, Wu D, Li W, Chen W, Liu P, Zhang H, Yang Y
Carbohydrate polymers 2024 May 15;332:121916
Carbohydrate polymers 2024 May 15;332:121916
IL-21-armored B7H3 CAR-iNKT cells exert potent antitumor effects.
Liu Y, Dang Y, Zhang C, Liu L, Cai W, Li L, Fang L, Wang M, Xu S, Wang G, Zheng J, Li H
iScience 2024 Jan 19;27(1):108597
iScience 2024 Jan 19;27(1):108597
Endogenous blocking of TLR2 along with TNF-α and IL-1β ameliorates the severity of the S. aureus arthritis via modulating STAT3/SOCS3 expressions in tissue resident macrophages.
Ghosh R, Bishayi B
Microbial pathogenesis 2024 Feb;187:106518
Microbial pathogenesis 2024 Feb;187:106518
Persistent tailoring of MSC activation through genetic priming.
Beauregard MA, Bedford GC, Brenner DA, Sanchez Solis LD, Nishiguchi T, Abhimanyu, Longlax SC, Mahata B, Veiseh O, Wenzel PL, DiNardo AR, Hilton IB, Diehl MR
bioRxiv : the preprint server for biology 2024 Feb 7;
bioRxiv : the preprint server for biology 2024 Feb 7;
Single cell analysis reveals the roles and regulatory mechanisms of type-I interferons in Parkinson's disease.
Quan P, Li X, Si Y, Sun L, Ding FF, Fan Y, Liu H, Wei C, Li R, Zhao X, Yang F, Yao L
Cell communication and signaling : CCS 2024 Apr 2;22(1):212
Cell communication and signaling : CCS 2024 Apr 2;22(1):212
Interferon inhibits a model RNA virus via a limited set of inducible effector genes.
McDougal MB, De Maria AM, Ohlson MB, Kumar A, Xing C, Schoggins JW
EMBO reports 2023 Sep 6;24(9):e56901
EMBO reports 2023 Sep 6;24(9):e56901
IL-17 promotes melanoma through TRAF2 as a scaffold protein recruiting PIAS2 and ELAVL1 to induce EPHA5.
Du J, Du Y, Chen L, Liu H
Biochimica et biophysica acta. Molecular cell research 2023 Oct;1870(7):119547
Biochimica et biophysica acta. Molecular cell research 2023 Oct;1870(7):119547
Silencing SIRT1 promotes the anti-HBV action of IFN-α by regulating Pol expression and activating the JAK-STAT signaling pathway.
Tang Q, Meng C, Liu Y, Cheng Y, Liu Y, Long Y, Sun S, Feng F
International immunopharmacology 2023 Nov;124(Pt B):110939
International immunopharmacology 2023 Nov;124(Pt B):110939
GSTM2 alleviates heart failure by inhibiting DNA damage in cardiomyocytes.
Xu H, Wang Z, Wang Y, Pan S, Zhao W, Chen M, Chen X, Tao T, Ma L, Ni Y, Li W
Cell & bioscience 2023 Nov 30;13(1):220
Cell & bioscience 2023 Nov 30;13(1):220
POR overexpression induces tamoxifen-resistance in breast cancer through the STAT1/c-Myc pathway.
Chen S, Wu D, Liu Q, Jin F, Yao F, Fang Y
Molecular carcinogenesis 2023 Feb;62(2):249-260
Molecular carcinogenesis 2023 Feb;62(2):249-260
Retinoic Acid Prevents α-Synuclein Preformed Fibrils-Induced Toxicity via Inhibiting STAT1-PARP1 Signaling.
Zhou L, Ma Z, Gao X
Molecular neurobiology 2023 Aug;60(8):4828-4841
Molecular neurobiology 2023 Aug;60(8):4828-4841
Free ISG15 inhibits Pseudorabies virus infection by positively regulating type I IFN signaling.
Liu H, Li C, He W, Chen J, Yang G, Chen L, Chang H
PLoS pathogens 2022 Oct;18(10):e1010921
PLoS pathogens 2022 Oct;18(10):e1010921
Proteome-centric cross-omics characterization and integrated network analyses of triple-negative breast cancer.
Gong TQ, Jiang YZ, Shao C, Peng WT, Liu MW, Li DQ, Zhang BY, Du P, Huang Y, Li FF, Li MY, Han ZL, Jin X, Ma D, Xiao Y, Yang PY, Qin J, Shao ZM, Zhu W
Cell reports 2022 Mar 1;38(9):110460
Cell reports 2022 Mar 1;38(9):110460
Panax notoginseng saponins prevent colitis-associated colorectal cancer via inhibition IDO1 mediated immune regulation.
Li XM, Yuan DY, Liu YH, Zhu L, Qin HK, Yang YB, Li Y, Yan F, Wang YJ
Chinese journal of natural medicines 2022 Apr;20(4):258-269
Chinese journal of natural medicines 2022 Apr;20(4):258-269
Dual Inhibition of Endoplasmic Reticulum Stress and Oxidation Stress Manipulates the Polarization of Macrophages under Hypoxia to Sensitize Immunotherapy.
Jiang M, Li X, Zhang J, Lu Y, Shi Y, Zhu C, Liu Y, Qin B, Luo Z, Du Y, Luo L, Peng L, You J
ACS nano 2021 Sep 28;15(9):14522-14534
ACS nano 2021 Sep 28;15(9):14522-14534
Comparative proteomics reveals Cryptosporidium parvum manipulation of the host cell molecular expression and immune response.
Li T, Liu H, Jiang N, Wang Y, Wang Y, Zhang J, Shen Y, Cao J
PLoS neglected tropical diseases 2021 Nov;15(11):e0009949
PLoS neglected tropical diseases 2021 Nov;15(11):e0009949
Statins attenuate antiviral IFN-β and ISG expression via inhibition of IRF3 and JAK/STAT signaling in poly(I:C)-treated hyperlipidemic mice and macrophages.
Koike A, Tsujinaka K, Fujimori K
The FEBS journal 2021 Jul;288(14):4249-4266
The FEBS journal 2021 Jul;288(14):4249-4266
Increased expression of IFN-γ in preeclampsia impairs human trophoblast invasion via a SOCS1/JAK/STAT1 feedback loop.
Liu H, Wang W, Liu C
Experimental and therapeutic medicine 2021 Feb;21(2):112
Experimental and therapeutic medicine 2021 Feb;21(2):112
Bicarbonate enhances the inflammatory response by activating JAK/STAT signalling in LPS + IFN-γ-stimulated macrophages.
Kawakami T, Koike A, Maehara T, Hayashi T, Fujimori K
Journal of biochemistry 2020 Jun 1;167(6):623-631
Journal of biochemistry 2020 Jun 1;167(6):623-631
Rhein attenuates renal inflammatory injury of uric acid nephropathy via lincRNA-Cox2/miR-150-5p/STAT1 axis.
Hu J, Yang Z, Wu H, Wang D
International immunopharmacology 2020 Aug;85:106620
International immunopharmacology 2020 Aug;85:106620
E2F2 directly regulates the STAT1 and PI3K/AKT/NF-κB pathways to exacerbate the inflammatory phenotype in rheumatoid arthritis synovial fibroblasts and mouse embryonic fibroblasts.
Wang S, Wang L, Wu C, Sun S, Pan JH
Arthritis research & therapy 2018 Oct 4;20(1):225
Arthritis research & therapy 2018 Oct 4;20(1):225
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