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- Antibody Data
- Antigen structure
- References [8]
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- Validations
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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- Product number
- HPA001595 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA001595, RRID:AB_1847814
- Product name
- Anti-DNMT3B
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human DNMT3B, Gene description: DNA (cytosine-5-)-methyltransferase 3 beta, Validated applications: ICC, IHC, WB, Uniprot ID: Q9UBC3, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references MiR-29b modulates DNA methylation in promoter region of miR-130b in mouse model of Diabetic nephropathy
Comparative oncology reveals DNMT3B as a molecular vulnerability in undifferentiated pleomorphic sarcoma
Developmental arsenic exposure impairs cognition, directly targets DNMT3A, and reduces DNA methylation
JAK-STAT inhibitor as a potential therapeutic opportunity in AML patients resistant to cytarabine and epigenetic therapy
Effect of CELSR3 on the Cell Cycle and Apoptosis of Hepatocellular Carcinoma Cells
Effects of high progesterone in in-vitro fertilization cycle on DNA methylation and gene expression of adhesion molecules on endometrium during implantation window
Circular RNA CpG island hypermethylation-associated silencing in human cancer
DNA methylation in demyelinated multiple sclerosis hippocampus
Gondaliya P, Jash K, Srivastava A, Kalia K
Journal of Diabetes & Metabolic Disorders 2023;22(2):1105-1115
Journal of Diabetes & Metabolic Disorders 2023;22(2):1105-1115
Comparative oncology reveals DNMT3B as a molecular vulnerability in undifferentiated pleomorphic sarcoma
Fuller A, DeVine A, Murazzi I, Mason N, Weber K, Eisinger-Mathason T
Cellular Oncology 2022;45(6):1277-1295
Cellular Oncology 2022;45(6):1277-1295
Developmental arsenic exposure impairs cognition, directly targets DNMT3A, and reduces DNA methylation
Yan N, Li Y, Xing Y, Wu J, Li J, Liang Y, Tang Y, Wang Z, Song H, Wang H, Xiao S, Lu M
EMBO reports 2022;23(6)
EMBO reports 2022;23(6)
JAK-STAT inhibitor as a potential therapeutic opportunity in AML patients resistant to cytarabine and epigenetic therapy
Babu G, Chaudhuri P, Rajappa M, Biswas M, Sansar B, Rajegowda C, Radhakrishnan A, Advani J, Tewary B, Radhakrishnan P, Thiyagarajan S, Chatterjee A, Upadhayaya R, Majumder P
Cancer Biology & Therapy 2020;22(1):66-78
Cancer Biology & Therapy 2020;22(1):66-78
Effect of CELSR3 on the Cell Cycle and Apoptosis of Hepatocellular Carcinoma Cells
Xie Z, Dang Y, Wu H, He R, Ma J, Peng Z, Rong M, Li Z, Yang J, Jiang Y, Chen G, Yang L
Journal of Cancer 2020;11(10):2830-2844
Journal of Cancer 2020;11(10):2830-2844
Effects of high progesterone in in-vitro fertilization cycle on DNA methylation and gene expression of adhesion molecules on endometrium during implantation window
Xiong Y, Hu L, Zhang T, Wang M, Xu H, Li T, Sun Y, Wang C
Journal of Assisted Reproduction and Genetics 2019;37(1):33-43
Journal of Assisted Reproduction and Genetics 2019;37(1):33-43
Circular RNA CpG island hypermethylation-associated silencing in human cancer
Ferreira H, Davalos V, de Moura M, Soler M, Perez-Salvia M, Bueno-Costa A, Setien F, Moran S, Villanueva A, Esteller M
Oncotarget 2018;9(49):29208-29219
Oncotarget 2018;9(49):29208-29219
DNA methylation in demyelinated multiple sclerosis hippocampus
Chomyk A, Volsko C, Tripathi A, Deckard S, Trapp B, Fox R, Dutta R
Scientific Reports 2017;7(1)
Scientific Reports 2017;7(1)
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & vesicles.
- Sample type
- Human
Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human testis and skeletal muscle tissues using HPA001595 antibody. Corresponding DNMT3B RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
