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- References [15]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 66157-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- C3/C3b/C3c antibody
- Antibody type
- Monoclonal
- Description
- C3/C3b/C3c antibody (Cat. #66157-1-Ig) is a mouse monoclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 2A6B3
- Vial size
- 20ul, 150ul
Submitted references HMGB1 dysregulation: a neuroimmune bridge to cognitive impairment in autoimmune thyroiditis.
A functional VCBP-C1q interaction in amphioxus reveals evolutionary origins of the classical complement pathway.
STAT3 inhibition ameliorates cognitive dysfunction in type 2 diabetes mellitus by modulating astrocytes via Nrf2 pathway activation.
EGCG-loaded nanoparticles attenuate post-SAH white matter injury by targeting HO-1/S100A10 to suppress oxidative stress-induced reactive astrocytes.
Panacis Quinquefolii Radix Polysaccharides Alleviate Depressive-Like Behaviors in Chronic Unpredictable Mild Stress-Induced Mice by Suppressing Complement C1Q/C3-Mediated Microglial Synaptic Pruning and Modulating Gut Microbiota.
Thermo-related degeneration of stumpy forms of Trypanosoma brucei, the pathogen of African sleeping sickness.
Author Correction: Fibroblast derived C3 promotes the progression of experimental periodontitis through macrophage M1 polarization and osteoclast differentiation.
Neutrophil extracellular trap-borne C3-driven endothelial dysfunction in Klebsiella pneumoniae liver abscess.
Regulatory T cells promote microglia-mediated synapse engulfment and functional recovery via the OPN-CD74 axis after spinal cord injury in mice.
Complement abnormality predisposes to the development of malignant hypertension-associated thrombotic microangiopathy disease.
Huanglian Jiedu Decoction improves the"central-peripheral"inflammatory microenvironment and enhances the cognitive function of APP/PS1 mice by inhibiting the activation of NLRP3 inflammasome mediated by gut microbiota.
Fibroblast derived C3 promotes the progression of experimental periodontitis through macrophage M1 polarization and osteoclast differentiation.
HylS', a fragment of truncated hyaluronidase of Streptococcus suis, contributes to immune evasion by interaction with host complement factor C3b.
Apelin alleviated neuroinflammation and promoted endogenous neural stem cell proliferation and differentiation after spinal cord injury in rats.
Quantitative iTRAQ-based proteomic analysis of piperine protected cerebral ischemia/reperfusion injury in rat brain.
Wang J, Chu G, Ding L, You W, Liu B, Xue H
Frontiers in immunology 2026;17:1764288
Frontiers in immunology 2026;17:1764288
A functional VCBP-C1q interaction in amphioxus reveals evolutionary origins of the classical complement pathway.
Gao J, Kang H, Wang L, Wang H, Gao Z
Molecular immunology 2026 May;193:123-134
Molecular immunology 2026 May;193:123-134
STAT3 inhibition ameliorates cognitive dysfunction in type 2 diabetes mellitus by modulating astrocytes via Nrf2 pathway activation.
Wang J, Chen P, Li Y, Wang R, Ding W, Yu R, Qin Q, Wu R, Wei W, Shi J, Yuan H, Zhuang C, Sun Y
Free radical biology & medicine 2026 Jun;249:165-179
Free radical biology & medicine 2026 Jun;249:165-179
EGCG-loaded nanoparticles attenuate post-SAH white matter injury by targeting HO-1/S100A10 to suppress oxidative stress-induced reactive astrocytes.
Lang D, Zheng Y, Zhang J, Li Z, Niu M, Wang J, Wang X, Huang L, Xue J, Li L, Chen Y
Redox report : communications in free radical research 2026 Dec 31;31(1):2664955
Redox report : communications in free radical research 2026 Dec 31;31(1):2664955
Panacis Quinquefolii Radix Polysaccharides Alleviate Depressive-Like Behaviors in Chronic Unpredictable Mild Stress-Induced Mice by Suppressing Complement C1Q/C3-Mediated Microglial Synaptic Pruning and Modulating Gut Microbiota.
Xie M, Feng L, Li R, Li M, Shen L, Zhang M, Wei Y, Yin Q, Wang D, Chen L, Song K, Wang P, Cong Q
CNS neuroscience & therapeutics 2026 Apr;32(4):e70859
CNS neuroscience & therapeutics 2026 Apr;32(4):e70859
Thermo-related degeneration of stumpy forms of Trypanosoma brucei, the pathogen of African sleeping sickness.
Luo JY, Wang JF, Yang J, Zhang P, Hide G, Lai DH, Lun ZR
Advanced biotechnology 2025 Sep 23;3(4):28
Advanced biotechnology 2025 Sep 23;3(4):28
Author Correction: Fibroblast derived C3 promotes the progression of experimental periodontitis through macrophage M1 polarization and osteoclast differentiation.
Ren F, Zheng S, Luo H, Yu X, Li X, Song S, Bu W, Sun H
International journal of oral science 2025 Jul 2;17(1):53
International journal of oral science 2025 Jul 2;17(1):53
Neutrophil extracellular trap-borne C3-driven endothelial dysfunction in Klebsiella pneumoniae liver abscess.
Wang H, Chen L, Wang C, Chang Z
Virulence 2025 Dec;16(1):2580104
Virulence 2025 Dec;16(1):2580104
Regulatory T cells promote microglia-mediated synapse engulfment and functional recovery via the OPN-CD74 axis after spinal cord injury in mice.
Liu R, Yan H, Liu X, Xie Y, Li Y, Wang Z, Huang H, Yu Z, Qu W, Wang M, Luo X
Journal of neuroinflammation 2025 Dec 15;23(1):21
Journal of neuroinflammation 2025 Dec 15;23(1):21
Complement abnormality predisposes to the development of malignant hypertension-associated thrombotic microangiopathy disease.
Lian R, Li W, Li Y, Lian X, Yu S, Shi W, Yu J, Chen W, Li J, He F
Clinical kidney journal 2025 Aug;18(8):sfaf235
Clinical kidney journal 2025 Aug;18(8):sfaf235
Huanglian Jiedu Decoction improves the"central-peripheral"inflammatory microenvironment and enhances the cognitive function of APP/PS1 mice by inhibiting the activation of NLRP3 inflammasome mediated by gut microbiota.
Zhang Y, Wang J, Li X, Guo R, Wang L, Liu Y, Yu Y, Kong L
Chinese medicine 2025 Aug 7;20(1):123
Chinese medicine 2025 Aug 7;20(1):123
Fibroblast derived C3 promotes the progression of experimental periodontitis through macrophage M1 polarization and osteoclast differentiation.
Ren F, Zheng S, Luo H, Yu X, Li X, Song S, Bu W, Sun H
International journal of oral science 2025 Apr 17;17(1):30
International journal of oral science 2025 Apr 17;17(1):30
HylS', a fragment of truncated hyaluronidase of Streptococcus suis, contributes to immune evasion by interaction with host complement factor C3b.
Xu J, Chen L, Pang S, Zhang Q, Deng S, Zhu J, Chen X, Langford PR, Huang Q, Zhou R, Li L
Virulence 2024 Dec;15(1):2306691
Virulence 2024 Dec;15(1):2306691
Apelin alleviated neuroinflammation and promoted endogenous neural stem cell proliferation and differentiation after spinal cord injury in rats.
Liu Q, Zhou S, Wang X, Gu C, Guo Q, Li X, Zhang C, Zhang N, Zhang L, Huang F
Journal of neuroinflammation 2022 Jun 20;19(1):160
Journal of neuroinflammation 2022 Jun 20;19(1):160
Quantitative iTRAQ-based proteomic analysis of piperine protected cerebral ischemia/reperfusion injury in rat brain.
Zou Y, Gong P, Zhao W, Zhang J, Wu X, Xin C, Xiong Z, Li Z, Wu X, Wan Q, Li X, Chen J
Neurochemistry international 2019 Mar;124:51-61
Neurochemistry international 2019 Mar;124:51-61
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human blood tissue were subjected to SDS PAGE followed by western blot with 66157-1-Ig( C3 Antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The C3 antibody from Proteintech is a mouse monoclonal antibody to a recombinant protein of human C3. This antibody recognizes human antigen. The C3 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
