Antibody data
- Antibody Data
- Antigen structure
- References [62]
- Comments [0]
- Validations
- Western blot [1]
Submit
Validation data
Reference
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- Product number
- 21337-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- C3/C3b/C3c antibody
- Antibody type
- Polyclonal
- Description
- C3/C3b/C3c antibody (Cat. #21337-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, rat, mouse and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Astrocytic purinergic signalling contributes to the development and maintenance of neuropathic pain via modulation of glutamate release.
Modulation of PKM2 inhibits follicular helper T cell differentiation and ameliorates inflammation in lupus-prone mice.
Effect of Myelin Debris on the Phenotypic Transformation of Astrocytes after Spinal Cord Injury in Rats.
Effect of total flavonoids of Dracocephalum moldavica L. On neuroinflammation in Alzheimer's disease model amyloid-β (Aβ1-42)-peptide-induced astrocyte activation.
Nuclear AGO2 promotes myocardial remodeling by activating ANKRD1 transcription in failing hearts.
Inhibition of aquaporin-4 and its subcellular localization attenuates below-level central neuropathic pain by regulating astrocyte activation in a rat spinal cord injury model.
Effectiveness of a novel rat model of off-target PLA2R1 knockout to renal impairment.
Extracellular vesicle biomarkers for complement dysfunction in schizophrenia.
Interior decorative volatile organic compounds exposure induces sleep disorders through aberrant branched chain amino acid transaminase 2 mediated glutamatergic signaling resulting from a neuroinflammatory cascade.
Integrin β1-rich extracellular vesicles of kidney recruit Fn1+ macrophages to aggravate ischemia-reperfusion-induced inflammation.
Microplastics exposure induced and exacerbated the development of systemic lupus erythematosus in mice.
Targeting blood brain barrier-Remote ischemic conditioning alleviates cognitive impairment in female APP/PS1 rats.
Balancing macrophage polarization via stem cell-derived apoptotic bodies for diabetic wound healing.
Complement components regulates ferroptosis in CVB3 viral myocarditis by interatction with TFRC.
Enriched Environment Inhibits Neurotoxic Reactive Astrocytes via JAK2-STAT3 to Promote Glutamatergic Synaptogenesis and Cognitive Improvement in Chronic Cerebral Hypoperfusion Rats.
KYNA Ameliorates Glutamate Toxicity of HAND by Enhancing Glutamate Uptake in A2 Astrocytes.
Complement C1q-mediated microglial synaptic elimination by enhancing desialylation underlies sevoflurane-induced developmental neurotoxicity.
Effects of liraglutide on astrocyte polarization and neuroinflammation in db/db mice: focus on iron overload and oxidative stress.
TIGIT-Fc fusion protein alleviates murine lupus nephritis through the regulation of SPI-B-PAX5-XBP1 axis-mediated B-cell differentiation.
The Oxysterol Receptor EBI2 Links Innate and Adaptive Immunity to Limit IFN Response and Systemic Lupus Erythematosus.
Knockout of microglial Hv1 proton channel reduces neurotoxic A1 astrocytes and neuronal damage via the ROS/STAT3 pathway after spinal cord injury.
Cell-specific NFIA upregulation promotes epileptogenesis by TRPV4-mediated astrocyte reactivity.
Repurposing crizotinib to target RIPK1-dependent cell death.
Kynurenic acid blunts A1 astrocyte activation against neurodegeneration in HIV-associated neurocognitive disorders.
Unrecognized Potent Activities of Colistin Against Clinically Important mcr+ Enterobacteriaceae Revealed in Synergy with Host Immunity.
Proteomics and transcriptomics profiling reveals distinct aspects of kidney stone related genes in calculi rats.
Blocking Two-Pore Domain Potassium Channel TREK-1 Inhibits the Activation of A1-Like Reactive Astrocyte Through the NF-κB Signaling Pathway in a Rat Model of Major Depressive Disorder.
Autophagy enables microglia to engage amyloid plaques and prevents microglial senescence.
Therapeutic hyperthermia regulates complement C3 activation and suppresses tumor development through HSPA5/NFκB/CD55 pathway in nasopharyngeal carcinoma.
Tandem Mass Tag-based proteomics analysis reveals the vital role of inflammation in traumatic brain injury in a mouse model.
PPARγ Acetylation Orchestrates Adipose Plasticity and Metabolic Rhythms.
HIF-1α participates in secondary brain injury through regulating neuroinflammation.
Qihuang Granule protects the retinal pigment epithelium from oxidative stress via regulation of the alternative complement pathway.
Neuron-Derived Exosomes Promote the Recovery of Spinal Cord Injury by Modulating Nerve Cells in the Cellular Microenvironment of the Lesion Area.
Inhibition of acid sphingomyelinase reduces reactive astrocyte secretion of mitotoxic extracellular vesicles and improves Alzheimer's disease pathology in the 5xFAD mouse.
Hemocompatibility tuning of an innovative glutaraldehyde-free preparation strategy using riboflavin/UV crosslinking and electron irradiation of bovine pericardium for cardiac substitutes.
Integrated transcriptomics and metabolomics analysis reveals that C3 and C5 are vital targets of DuZhi Wan in protecting against cerebral ischemic injury.
SIRT3 alleviates mitochondrial dysfunction induced by recurrent low glucose and improves the supportive function of astrocytes to neurons.
Cyanidin-3-O-glucoside ameliorates cadmium induced uterine epithelium proliferation in mice.
Natural antibodies and CRP drive anaphylatoxin production by urate crystals.
1,25-dihydroxyvitamin D3 ameliorates lupus nephritis through inhibiting the NF-κB and MAPK signalling pathways in MRL/lpr mice.
Total coumarin derivates from Hydrangea paniculata attenuate renal injuries in cationized-BSA induced membranous nephropathy by inhibiting complement activation and interleukin 10-mediated interstitial fibrosis.
Pandemic Influenza Infection Promotes Streptococcus pneumoniae Infiltration, Necrotic Damage, and Proteomic Remodeling in the Heart.
Cornuside Is a Potential Agent against Alzheimer's Disease via Orchestration of Reactive Astrocytes.
Activation of C3 and C5 May Be Involved in the Inflammatory Progression of PCM and GM.
Sequence analysis and function of mosquito aeCCC2 and Drosophila Ncc83 orthologs.
Exogenous Biological Renal Support Improves Kidney Function in Mice With Rhabdomyolysis-Induced Acute Kidney Injury.
Proteomic Landscape of Exosomes Reveals the Functional Contributions of CD151 in Triple-Negative Breast Cancer.
Extracellular vesicles derived from CD73 modified human umbilical cord mesenchymal stem cells ameliorate inflammation after spinal cord injury.
Complement C3 Aggravates Post-epileptic Neuronal Injury Via Activation of TRPV1.
Cholecystokinin octapeptide improves hippocampal glutamatergic synaptogenesis and postoperative cognition by inhibiting induction of A1 reactive astrocytes in aged mice.
Adipsin promotes bone marrow adiposity by priming mesenchymal stem cells.
Silencing of circIgf1r plays a protective role in neuronal injury via regulating astrocyte polarization during epilepsy.
Yak milk-derived exosomes alleviate lipopolysaccharide-induced intestinal inflammation by inhibiting PI3K/AKT/C3 pathway activation.
Increased circulating levels of Factor H-Related Protein 4 are strongly associated with age-related macular degeneration.
C-reactive protein (CRP) recognizes uric acid crystals and recruits proteases C1 and MASP1.
The Surface-Exposed Protein SntA Contributes to Complement Evasion in Zoonotic Streptococcus suis.
4-Hydroxy-7-oxo-5-heptenoic Acid Lactone Is a Potent Inducer of the Complement Pathway in Human Retinal Pigmented Epithelial Cells.
Differential protein analysis of serum exosomes post-intravenous immunoglobulin therapy in patients with Kawasaki disease.
Generation of complement protein C3 deficient pigs by CRISPR/Cas9-mediated gene targeting.
Serum estradiol levels in controlled ovarian stimulation directly affect the endometrium.
Identification of Potential Biomarkers for Rhegmatogenous Retinal Detachment Associated with Choroidal Detachment by Vitreous iTRAQ-Based Proteomic Profiling.
Liu S, Cheng H, Cui L, Jin L, Li Y, Zhu C, Ji Q, Tang J
Journal of neurochemistry 2024 Nov;168(11):3727-3744
Journal of neurochemistry 2024 Nov;168(11):3727-3744
Modulation of PKM2 inhibits follicular helper T cell differentiation and ameliorates inflammation in lupus-prone mice.
Lin M, Huang L, Huang J, Yu J, Yang X, Yang J
Journal of autoimmunity 2024 May;145:103198
Journal of autoimmunity 2024 May;145:103198
Effect of Myelin Debris on the Phenotypic Transformation of Astrocytes after Spinal Cord Injury in Rats.
Lv J, Yu H, Shan F, Ye J, Li A, Jing J, Zheng M, Tian D
Neuroscience 2024 May 24;547:1-16
Neuroscience 2024 May 24;547:1-16
Effect of total flavonoids of Dracocephalum moldavica L. On neuroinflammation in Alzheimer's disease model amyloid-β (Aβ1-42)-peptide-induced astrocyte activation.
Ren W, Yan XS, Fan JC, Huo DS, Wang XX, Jia JX, Yang ZJ
Journal of toxicology and environmental health. Part A 2024 May 18;87(10):436-447
Journal of toxicology and environmental health. Part A 2024 May 18;87(10):436-447
Nuclear AGO2 promotes myocardial remodeling by activating ANKRD1 transcription in failing hearts.
Xie R, Yuan S, Hu G, Zhan J, Jin K, Tang Y, Fan J, Zhao Y, Wang F, Chen C, Wang DW, Li H
Molecular therapy : the journal of the American Society of Gene Therapy 2024 May 1;32(5):1578-1594
Molecular therapy : the journal of the American Society of Gene Therapy 2024 May 1;32(5):1578-1594
Inhibition of aquaporin-4 and its subcellular localization attenuates below-level central neuropathic pain by regulating astrocyte activation in a rat spinal cord injury model.
Song Y, Xue T, Guo S, Yu Z, Yun C, Zhao J, Song Z, Liu Z
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2024 Mar;21(2):e00306
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2024 Mar;21(2):e00306
Effectiveness of a novel rat model of off-target PLA2R1 knockout to renal impairment.
Huang B, Zhang Z, Sui W, Zhao L, Li Y, Feng L, Yang D, Zhou Y
Genomics 2024 Mar;116(2):110796
Genomics 2024 Mar;116(2):110796
Extracellular vesicle biomarkers for complement dysfunction in schizophrenia.
Xue T, Liu W, Wang L, Shi Y, Hu Y, Yang J, Li G, Huang H, Cui D
Brain : a journal of neurology 2024 Mar 1;147(3):1075-1086
Brain : a journal of neurology 2024 Mar 1;147(3):1075-1086
Interior decorative volatile organic compounds exposure induces sleep disorders through aberrant branched chain amino acid transaminase 2 mediated glutamatergic signaling resulting from a neuroinflammatory cascade.
Zheng J, Wu M, Pang Y, Liu Q, Liu Y, Jin X, Tang J, Bao L, Niu Y, Zheng Y, Zhang R
The Science of the total environment 2024 Jul 15;934:173254
The Science of the total environment 2024 Jul 15;934:173254
Integrin β1-rich extracellular vesicles of kidney recruit Fn1+ macrophages to aggravate ischemia-reperfusion-induced inflammation.
Wang W, Ren X, Chen X, Hong Q, Cai G
JCI insight 2024 Jan 23;9(2)
JCI insight 2024 Jan 23;9(2)
Microplastics exposure induced and exacerbated the development of systemic lupus erythematosus in mice.
Chen H, Wan L, Qiu Y, Qiu F, Wen C, Mao Y, He Z
The Science of the total environment 2024 Jan 20;909:168586
The Science of the total environment 2024 Jan 20;909:168586
Targeting blood brain barrier-Remote ischemic conditioning alleviates cognitive impairment in female APP/PS1 rats.
Ma Y, Sun W, Bai J, Gao F, Ma H, Liu H, Hu J, Xu C, Zhang X, Liu Z, Yuan T, Sun C, Huang Y, Wang R
CNS neuroscience & therapeutics 2024 Feb;30(2):e14613
CNS neuroscience & therapeutics 2024 Feb;30(2):e14613
Balancing macrophage polarization via stem cell-derived apoptotic bodies for diabetic wound healing.
Mao J, Qian S, Zhao Q, Zhao B, Lu B, Zhang L, Mao X, Zhang Y, Cui W, Sun X
Med (New York, N.Y.) 2024 Feb 9;5(2):148-168.e8
Med (New York, N.Y.) 2024 Feb 9;5(2):148-168.e8
Complement components regulates ferroptosis in CVB3 viral myocarditis by interatction with TFRC.
Yi L, Yang Y, Hu Y, Wu Z, Kong M, Zuoyuan B, Xin X, Yang Z
Free radical biology & medicine 2024 Feb 20;212:349-359
Free radical biology & medicine 2024 Feb 20;212:349-359
Enriched Environment Inhibits Neurotoxic Reactive Astrocytes via JAK2-STAT3 to Promote Glutamatergic Synaptogenesis and Cognitive Improvement in Chronic Cerebral Hypoperfusion Rats.
Fan B, Lin J, Luo Q, Liao W, Hao C
Neurotoxicity research 2024 Apr 2;42(2):22
Neurotoxicity research 2024 Apr 2;42(2):22
KYNA Ameliorates Glutamate Toxicity of HAND by Enhancing Glutamate Uptake in A2 Astrocytes.
Chen J, Zou J, Huang P, Gao X, Lun J, Li Y, Gong Z, Cao H
International journal of molecular sciences 2024 Apr 12;25(8)
International journal of molecular sciences 2024 Apr 12;25(8)
Complement C1q-mediated microglial synaptic elimination by enhancing desialylation underlies sevoflurane-induced developmental neurotoxicity.
Wang G, Liu HY, Meng XW, Chen Y, Zhao WM, Li WT, Xu HB, Peng K, Ji FH
Cell & bioscience 2024 Apr 1;14(1):42
Cell & bioscience 2024 Apr 1;14(1):42
Effects of liraglutide on astrocyte polarization and neuroinflammation in db/db mice: focus on iron overload and oxidative stress.
An JR, Liu JT, Gao XM, Wang QF, Sun GY, Su JN, Zhang C, Yu JX, Yang YF, Shi Y
Frontiers in cellular neuroscience 2023;17:1136070
Frontiers in cellular neuroscience 2023;17:1136070
TIGIT-Fc fusion protein alleviates murine lupus nephritis through the regulation of SPI-B-PAX5-XBP1 axis-mediated B-cell differentiation.
Zhao J, Li L, Feng X, Gao C, Gao L, Zhan Y, Wang Z, Zhao M, Yin H, Lu Q
Journal of autoimmunity 2023 Sep;139:103087
Journal of autoimmunity 2023 Sep;139:103087
The Oxysterol Receptor EBI2 Links Innate and Adaptive Immunity to Limit IFN Response and Systemic Lupus Erythematosus.
Zhang F, Zhang B, Ding H, Li X, Wang X, Zhang X, Liu Q, Feng Q, Han M, Chen L, Qi L, Yang D, Li X, Zhu X, Zhao Q, Qiu J, Zhu Z, Tang H, Shen N, Wang H, Wei B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(27):e2207108
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(27):e2207108
Knockout of microglial Hv1 proton channel reduces neurotoxic A1 astrocytes and neuronal damage via the ROS/STAT3 pathway after spinal cord injury.
Li Y, Xie Y, Liu R, Wang Z, Chen P, Wang M, Yu Z, Wang W, Luo X
Glia 2023 Oct;71(10):2418-2436
Glia 2023 Oct;71(10):2418-2436
Cell-specific NFIA upregulation promotes epileptogenesis by TRPV4-mediated astrocyte reactivity.
Kong S, Chen TX, Jia XL, Cheng XL, Zeng ML, Liang JY, He XH, Yin J, Han S, Liu WH, Fan YT, Zhou T, Liu YM, Peng BW
Journal of neuroinflammation 2023 Oct 25;20(1):247
Journal of neuroinflammation 2023 Oct 25;20(1):247
Repurposing crizotinib to target RIPK1-dependent cell death.
Yu Y, Li M, Fu S, He X, Hu X, Zhu G, Wang J, You X, Mou Y, Ye Z, Wei J, Zha Y
International immunology 2023 May 8;35(5):221-230
International immunology 2023 May 8;35(5):221-230
Kynurenic acid blunts A1 astrocyte activation against neurodegeneration in HIV-associated neurocognitive disorders.
Lun J, Li Y, Gao X, Gong Z, Chen X, Zou J, Zhou C, Huang Y, Zhou B, Huang P, Cao H
Journal of neuroinflammation 2023 Mar 30;20(1):87
Journal of neuroinflammation 2023 Mar 30;20(1):87
Unrecognized Potent Activities of Colistin Against Clinically Important mcr+ Enterobacteriaceae Revealed in Synergy with Host Immunity.
Kumaraswamy M, Riestra A, Flores A, Uchiyama S, Dahesh S, Bondsäter G, Nilsson V, Chang M, Seo H, Sakoulas G, Nizet V
bioRxiv : the preprint server for biology 2023 Mar 21;
bioRxiv : the preprint server for biology 2023 Mar 21;
Proteomics and transcriptomics profiling reveals distinct aspects of kidney stone related genes in calculi rats.
Zhu W, Qiong D, Yanli G, Min L, Ying Z, Qiyi H, Shenping Z, Xisheng W, Hui L
BMC genomics 2023 Mar 17;24(1):127
BMC genomics 2023 Mar 17;24(1):127
Blocking Two-Pore Domain Potassium Channel TREK-1 Inhibits the Activation of A1-Like Reactive Astrocyte Through the NF-κB Signaling Pathway in a Rat Model of Major Depressive Disorder.
Cong T, Sun Y, Zhou Y, Wu H, Li L, Chu Z, Chen X, Li J, Zhao D, Wang Y, Liu Y, Yin S, Xiao Z
Neurochemical research 2023 Jun;48(6):1737-1754
Neurochemical research 2023 Jun;48(6):1737-1754
Autophagy enables microglia to engage amyloid plaques and prevents microglial senescence.
Choi I, Wang M, Yoo S, Xu P, Seegobin SP, Li X, Han X, Wang Q, Peng J, Zhang B, Yue Z
Nature cell biology 2023 Jul;25(7):963-974
Nature cell biology 2023 Jul;25(7):963-974
Therapeutic hyperthermia regulates complement C3 activation and suppresses tumor development through HSPA5/NFκB/CD55 pathway in nasopharyngeal carcinoma.
Chen C, Ren A, Yi Q, Cai J, Khan M, Lin Y, Huang Z, Lin J, Zhang J, Liu W, Xu A, Tian Y, Yuan Y, Zheng R
Clinical and experimental immunology 2023 Jul 21;213(2):221-234
Clinical and experimental immunology 2023 Jul 21;213(2):221-234
Tandem Mass Tag-based proteomics analysis reveals the vital role of inflammation in traumatic brain injury in a mouse model.
Dong JQ, Ge QQ, Lu SH, Yang MS, Zhuang Y, Zhang B, Niu F, Xu XJ, Liu BY
Neural regeneration research 2023 Jan;18(1):155-161
Neural regeneration research 2023 Jan;18(1):155-161
PPARγ Acetylation Orchestrates Adipose Plasticity and Metabolic Rhythms.
He Y, B'nai Taub A, Yu L, Yao Y, Zhang R, Zahr T, Aaron N, LeSauter J, Fan L, Liu L, Tazebay R, Que J, Pajvani U, Wang L, Silver R, Qiang L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jan;10(2):e2204190
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jan;10(2):e2204190
HIF-1α participates in secondary brain injury through regulating neuroinflammation.
Xu X, Yang M, Zhang B, Dong J, Zhuang Y, Ge Q, Niu F, Liu B
Translational neuroscience 2023 Jan 1;14(1):20220272
Translational neuroscience 2023 Jan 1;14(1):20220272
Qihuang Granule protects the retinal pigment epithelium from oxidative stress via regulation of the alternative complement pathway.
Wang Y, Shen H, Pang L, Qiu B, Yuan Y, Guan X, Xiang X
BMC complementary medicine and therapies 2023 Feb 18;23(1):55
BMC complementary medicine and therapies 2023 Feb 18;23(1):55
Neuron-Derived Exosomes Promote the Recovery of Spinal Cord Injury by Modulating Nerve Cells in the Cellular Microenvironment of the Lesion Area.
Xu Y, Zhu ZH, Xu X, Sun HT, Zheng HM, Zhang JL, Wang HH, Fang JW, Liu YZ, Huang LL, Song ZW, Liu JB
Molecular neurobiology 2023 Aug;60(8):4502-4516
Molecular neurobiology 2023 Aug;60(8):4502-4516
Inhibition of acid sphingomyelinase reduces reactive astrocyte secretion of mitotoxic extracellular vesicles and improves Alzheimer's disease pathology in the 5xFAD mouse.
Crivelli SM, Quadri Z, Vekaria HJ, Zhu Z, Tripathi P, Elsherbini A, Zhang L, Sullivan PG, Bieberich E
Acta neuropathologica communications 2023 Aug 21;11(1):135
Acta neuropathologica communications 2023 Aug 21;11(1):135
Hemocompatibility tuning of an innovative glutaraldehyde-free preparation strategy using riboflavin/UV crosslinking and electron irradiation of bovine pericardium for cardiac substitutes.
Dittfeld C, Welzel C, König U, Jannasch A, Alexiou K, Blum E, Bronder S, Sperling C, Maitz MF, Tugtekin SM
Biomaterials advances 2023 Apr;147:213328
Biomaterials advances 2023 Apr;147:213328
Integrated transcriptomics and metabolomics analysis reveals that C3 and C5 are vital targets of DuZhi Wan in protecting against cerebral ischemic injury.
Hou JY, Cao GZ, Tian LL, Zhou R, Zhang Y, Xu H, Wu HW, Wang LF, Yang HJ, Zhang JJ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113703
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113703
SIRT3 alleviates mitochondrial dysfunction induced by recurrent low glucose and improves the supportive function of astrocytes to neurons.
Gao R, Chen Z, Wu Y, Chen R, Zheng W, Qi L, Liu X, Liu X, Liu L
Free radical biology & medicine 2022 Nov 20;193(Pt 1):405-420
Free radical biology & medicine 2022 Nov 20;193(Pt 1):405-420
Cyanidin-3-O-glucoside ameliorates cadmium induced uterine epithelium proliferation in mice.
Yang D, Ran Y, Li X, Jiang X, Chen J, Sun J, Tian L, Teerds K, Bai W
Journal of hazardous materials 2022 Mar 5;425:127571
Journal of hazardous materials 2022 Mar 5;425:127571
Natural antibodies and CRP drive anaphylatoxin production by urate crystals.
Wessig AK, Hoffmeister L, Klingberg A, Alberts A, Pich A, Brand K, Witte T, Neumann K
Scientific reports 2022 Mar 16;12(1):4483
Scientific reports 2022 Mar 16;12(1):4483
1,25-dihydroxyvitamin D3 ameliorates lupus nephritis through inhibiting the NF-κB and MAPK signalling pathways in MRL/lpr mice.
Li X, Liu J, Zhao Y, Xu N, Lv E, Ci C, Li X
BMC nephrology 2022 Jul 8;23(1):243
BMC nephrology 2022 Jul 8;23(1):243
Total coumarin derivates from Hydrangea paniculata attenuate renal injuries in cationized-BSA induced membranous nephropathy by inhibiting complement activation and interleukin 10-mediated interstitial fibrosis.
Wang W, Sheng L, Chen Y, Li Z, Wu H, Ma J, Zhang D, Chen X, Zhang S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Feb;96:153886
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Feb;96:153886
Pandemic Influenza Infection Promotes Streptococcus pneumoniae Infiltration, Necrotic Damage, and Proteomic Remodeling in the Heart.
Platt MP, Lin YH, Wiscovitch-Russo R, Yu Y, Gonzalez-Juarbe N
mBio 2022 Feb 22;13(1):e0325721
mBio 2022 Feb 22;13(1):e0325721
Cornuside Is a Potential Agent against Alzheimer's Disease via Orchestration of Reactive Astrocytes.
Shi JZ, Zheng XM, Zhou YF, Yun LY, Luo DM, Hao JJ, Liu PF, Zhang WK, Xu JK, Yan Y, Xie XM, He YY, Pang XB
Nutrients 2022 Aug 3;14(15)
Nutrients 2022 Aug 3;14(15)
Activation of C3 and C5 May Be Involved in the Inflammatory Progression of PCM and GM.
Li XQ, Sun HG, Wang XH, Zhang HJ, Zhang XS, Yu Y, Liu J, Guo QQ, Yang ZL
Inflammation 2022 Apr;45(2):739-752
Inflammation 2022 Apr;45(2):739-752
Sequence analysis and function of mosquito aeCCC2 and Drosophila Ncc83 orthologs.
Duong PC, McCabe TC, Riley GF, Holmes HL, Piermarini PM, Romero MF, Gillen CM
Insect biochemistry and molecular biology 2022 Apr;143:103729
Insect biochemistry and molecular biology 2022 Apr;143:103729
Exogenous Biological Renal Support Improves Kidney Function in Mice With Rhabdomyolysis-Induced Acute Kidney Injury.
Liu C, Chi K, Geng X, Hong Q, Mao Z, Huang Q, Liu D, Wang Y, Zhang Y, Zhou F, Cai G, Chen X, Sun X
Frontiers in medicine 2021;8:655787
Frontiers in medicine 2021;8:655787
Proteomic Landscape of Exosomes Reveals the Functional Contributions of CD151 in Triple-Negative Breast Cancer.
Li S, Li X, Yang S, Pi H, Li Z, Yao P, Zhang Q, Wang Q, Shen P, Li X, Ji J
Molecular & cellular proteomics : MCP 2021;20:100121
Molecular & cellular proteomics : MCP 2021;20:100121
Extracellular vesicles derived from CD73 modified human umbilical cord mesenchymal stem cells ameliorate inflammation after spinal cord injury.
Zhai X, Chen K, Yang H, Li B, Zhou T, Wang H, Zhou H, Chen S, Zhou X, Wei X, Bai Y, Li M
Journal of nanobiotechnology 2021 Sep 8;19(1):274
Journal of nanobiotechnology 2021 Sep 8;19(1):274
Complement C3 Aggravates Post-epileptic Neuronal Injury Via Activation of TRPV1.
Jiang GT, Shao L, Kong S, Zeng ML, Cheng JJ, Chen TX, Han S, Yin J, Liu WH, He XH, Liu YM, Gongga L, Peng BW
Neuroscience bulletin 2021 Oct;37(10):1427-1440
Neuroscience bulletin 2021 Oct;37(10):1427-1440
Cholecystokinin octapeptide improves hippocampal glutamatergic synaptogenesis and postoperative cognition by inhibiting induction of A1 reactive astrocytes in aged mice.
Chen L, Yang N, Li Y, Li Y, Hong J, Wang Q, Liu K, Han D, Han Y, Mi X, Shi C, Zhou Y, Li Z, Liu T, Guo X
CNS neuroscience & therapeutics 2021 Nov;27(11):1374-1384
CNS neuroscience & therapeutics 2021 Nov;27(11):1374-1384
Adipsin promotes bone marrow adiposity by priming mesenchymal stem cells.
Aaron N, Kraakman MJ, Zhou Q, Liu Q, Costa S, Yang J, Liu L, Yu L, Wang L, He Y, Fan L, Hirakawa H, Ding L, Lo J, Wang W, Zhao B, Guo E, Sun L, Rosen CJ, Qiang L
eLife 2021 Jun 22;10
eLife 2021 Jun 22;10
Silencing of circIgf1r plays a protective role in neuronal injury via regulating astrocyte polarization during epilepsy.
Shao L, Jiang GT, Yang XL, Zeng ML, Cheng JJ, Kong S, Dong X, Chen TX, Han S, Yin J, Liu WH, He XH, He C, Peng BW
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21330
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21330
Yak milk-derived exosomes alleviate lipopolysaccharide-induced intestinal inflammation by inhibiting PI3K/AKT/C3 pathway activation.
Gao HN, Hu H, Wen PC, Lian S, Xie XL, Song HL, Yang ZN, Ren FZ
Journal of dairy science 2021 Aug;104(8):8411-8424
Journal of dairy science 2021 Aug;104(8):8411-8424
Increased circulating levels of Factor H-Related Protein 4 are strongly associated with age-related macular degeneration.
Cipriani V, Lorés-Motta L, He F, Fathalla D, Tilakaratna V, McHarg S, Bayatti N, Acar İE, Hoyng CB, Fauser S, Moore AT, Yates JRW, de Jong EK, Morgan BP, den Hollander AI, Bishop PN, Clark SJ
Nature communications 2020 Feb 7;11(1):778
Nature communications 2020 Feb 7;11(1):778
C-reactive protein (CRP) recognizes uric acid crystals and recruits proteases C1 and MASP1.
Alberts A, Klingberg A, Wessig AK, Combes C, Witte T, Brand K, Pich A, Neumann K
Scientific reports 2020 Apr 14;10(1):6391
Scientific reports 2020 Apr 14;10(1):6391
The Surface-Exposed Protein SntA Contributes to Complement Evasion in Zoonotic Streptococcus suis.
Deng S, Xu T, Fang Q, Yu L, Zhu J, Chen L, Liu J, Zhou R
Frontiers in immunology 2018;9:1063
Frontiers in immunology 2018;9:1063
4-Hydroxy-7-oxo-5-heptenoic Acid Lactone Is a Potent Inducer of the Complement Pathway in Human Retinal Pigmented Epithelial Cells.
Linetsky M, Bondelid KS, Losovskiy S, Gabyak V, Rullo MJ, Stiadle TI, Munjapara V, Saxena P, Ma D, Cheng YS, Howes AM, Udeigwe E, Salomon RG
Chemical research in toxicology 2018 Aug 20;31(8):666-679
Chemical research in toxicology 2018 Aug 20;31(8):666-679
Differential protein analysis of serum exosomes post-intravenous immunoglobulin therapy in patients with Kawasaki disease.
Zhang L, Song QF, Jin JJ, Huang P, Wang ZP, Xie XF, Gu XQ, Gao XJ, Jia HL
Cardiology in the young 2017 Nov;27(9):1786-1796
Cardiology in the young 2017 Nov;27(9):1786-1796
Generation of complement protein C3 deficient pigs by CRISPR/Cas9-mediated gene targeting.
Zhang W, Wang G, Wang Y, Jin Y, Zhao L, Xiong Q, Zhang L, Mou L, Li R, Yang H, Dai Y
Scientific reports 2017 Jul 10;7(1):5009
Scientific reports 2017 Jul 10;7(1):5009
Serum estradiol levels in controlled ovarian stimulation directly affect the endometrium.
Ullah K, Rahman TU, Pan HT, Guo MX, Dong XY, Liu J, Jin LY, Cheng Y, Ke ZH, Ren J, Lin XH, Qiu XX, Wang TT, Huang HF, Sheng JZ
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The C3 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human C3. This antibody recognizes human antigen. The C3 antibody has been validated for the following applications: ELISA, WB analysis.