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- Product number
- 21337-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- C3/C3b/C3c antibody
- Antibody type
- Polyclonal
- Description
- C3/C3b/C3c antibody (Cat. #21337-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, rat, mouse and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Single-Nucleus Transcriptomics Reveals Microglial State Transitions and Astrocytic Trajectory Divergence During Glial Remodeling Induced by Intracortical Electrode Implantation.
Time-dependent neuroprotective effects of YL-IPA08 in repetitive mild traumatic brain injury associated with changes in Caprin1/SHH signaling.
ACSL4-mediated astrocyte ferroptosis augments neuroinflammation and exacerbates NMOSD pathology.
Ovarian Matrisome Dynamics and αvβ3-Mediated Regulation in Early Follicular Development.
Astrocyte-Specific Nrf2 Expression Transforms Neurotoxic Reactive Astrocytes to Neuroprotective Phenotype in 3xTg-AD Mice.
MAFG Induces the Methylation of CRYAB to Promote the Activation of A1 Astrocyte After Spinal Cord Injury.
Fecal microbiota transplantation promotes Wnt3a-mediated hippocampal neurogenesis in a rat model of chronic cerebral hypoperfusion.
Comprehensive Transcriptomic Profiling Reveals Rotavirus-Induced Alterations in Both Coding and Long Non-Coding RNA Expression in MA104 Cells.
Integrated Profiling of DEHP-Induced Hippocampal Neurotoxicity in Adult Female Rats Based on Transcriptomic and Neurobiological Analyses.
C5aR1(+) microglia exacerbate neuroinflammation and cerebral edema in acute brain injury.
Helicobacter pylori-Induced Inflammatory Cancer Transformation Microenvironment Drives Gastric Carcinogenesis.
Tocilizumab-loaded nanoparticles block IL-6R and reduce edema after intracerebral hemorrhage.
Wzi modulates immune evasion of hypervirulent Klebsiella pneumoniae in a CPS-dependent and independent manner.
Gut microbial ammonia as a mediator of PFOS neurotoxicity and its remediation by the flavonoid Icaritin.
YAP Regulates Microglial Anti-Inflammatory Responses and Alleviates Cognitive Impairment Through the IL-33/ST2 Pathway after Traumatic Brain Injury.
Polydopamine-Encapsulated Probiotics Restore Gut Homeostasis and Reinstate Macrophage Efferocytosis in Systemic Lupus Erythematosus.
Deciphering Apolipoprotein A4 in the Protein Corona of Ligand-Modified Liposomes for Tumor Targeting and Penetration.
Xuming tongmai decoction modulates astrocyte polarization and mitophagy via the PINK1/Parkin pathway in a rat model of acute ischemic stroke.
Biosynthesis of Lysosomally Escaped Apoptotic Bodies Inhibits Inflammasome Synthesis in Macrophages.
Vincristine Regulates C/EBP-β/TGF-β1 to Promote A1 Astrocyte Polarization and Induce Neuropathic Pain.
Cholecystokinin ameliorates cognitive impairment via inhibiting microglia phagocytosis of excitatory synapses in sepsis-associated encephalopathy mice.
Penthorum chinense Pursh extract ameliorates lupus nephritis disease in MRL/lpr mice via the PPARγ/NFκB signaling axis.
Echinacoside targets the HIF-1α/LDHA axis to modulate A1/A2 astrocyte differentiation and promote glial scar repair following ischemic stroke.
Transcription factor RUNX2 participates in astrocyte-mediated neuropathic pain via transcriptional activation of Ccl2.
Microglia in the Rostral Ventromedial Medulla Mediate Synaptic Pruning via the C1q/C3-CR3 Signaling Pathway-A Mechanism for the Chronic Orofacial Pain.
Rutin ameliorates sevoflurane-induced neurotoxicity by inhibiting microglial synaptic phagocytosis through the complement pathway.
Activation of the C3 Complement Pathway in the Hippocampus Produces Anxiodepressive Effects in a Mouse Model of Inflammation Pain.
hADMSC-Evs attenuates depressive and anxiety - like behaviors in chronic liver disease via suppressing Liver-Brain Galectin3 signaling.
Microglial activation drives neuronal dysregulation in alcohol-induced seizure susceptibility.
A1-Reactive Astrocytes in the Posterior Part of Paraventricular Thalamic Nucleus Are Involved in Pain Modulation in Mice.
Aspirin Attenuates the Pathogenesis of Amyotrophic Lateral Sclerosis by Inhibiting the Activities of Microglia in a NF-κB-dependent Complement System-deactivating Mechanism.
GRP78 alleviates secondary brain injury by regulating phenotype polarization in astrocytes via JAK2-STAT3 pathway after intracerebral hemorrhage.
Electroacupuncture Alleviates Cerebral Ischemia-Reperfusion Injury by Downregulating IL-17 A and Inhibiting Neurotoxic Astrocyte Activation.
Potentiated fractalkine signaling axis affects neuroinflammation in 1,2-dichloroethane- intoxicated mice via divergent modulating ways on microglial hyperactivation.
Xixin Decoction May Treat Vascular Dementia by Modulating the NPTX2/C1q/C3 Complement Pathway.
PDE4 inhibition alleviates HMGB1/C1q/C3-mediated excessive phagocytic pruning of synapses by microglia and depressive-like behaviors in mice.
Microbiota-Derived Inosine Suppresses Systemic Autoimmunity via Restriction of B Cell Differentiation and Migration.
Ficolin-3 Activates Complement and Triggers Necroptosis in Cholangiocarcinoma Cells via the RIPK1/RIPK3/MLKL Signaling Pathway.
Capsazepine Inhibits Astrocyte Activation and Attenuates Neuroinflammation by Targeting Syntaxin 7.
Inhibition of S100A4 decreases neurotoxic astrocyte reactivity and attenuates neuropathic pain via the TLR4/NF-κB pathway in a rat model of spinal nerve ligation.
Therapeutic effect of pH responsive Magainin II modified azithromycin plus curcumin micelles in different depth models of MRSA infection.
TNF-α mediates activation of neuronal necroptotic signaling in rat with syringomyelia.
Astragalin-functionalized ultrasmall nanoparticles modulate the complement pathway to inhibit microglial synaptic phagocytosis for reducing anesthetic neurotoxicity.
Acupuncture regulates astrocyte neurotoxic polarization to protect blood-brain barrier integrity in delayed thrombolysis through mediating ERK1/2/Cx43 axis.
Multi-omics analysis reveals metabolic disruptions in cardiac tissues of aging nonhuman primates with spontaneous type 2 diabetes.
Colistin exerts potent activity against mcr+ Enterobacteriaceae via synergistic interactions with the host defense.
GABA-dependent microglial elimination of inhibitory synapses underlies neuronal hyperexcitability in epilepsy.
A novel IgD-FcδR blocker, IgD-Fc-Ig fusion protein, effectively alleviates abnormal activation of T cells the disease progression in systemic lupus erythematosus.
Effectiveness of a Novel PLA2R1 Knock-In Rat Model in Repairing Renal Function Damage.
C3/C3aR Bridges Spinal Astrocyte-Microglia Crosstalk and Accelerates Neuroinflammation in Morphine-Tolerant Rats.
Tracking astrocyte polarization in the retina in retinopathy of prematurity.
Astrocyte-neuron communication through the complement C3-C3aR pathway in Parkinson's disease.
Therapeutic potential of simvastatin in ALS: Enhanced axonal integrity and motor neuron survival through Apoa4 and Alb modulation.
TDP43 augments astrocyte inflammatory activity through mtDNA-cGAS-STING axis in NMOSD.
Glucosyl Hesperidin Supplementation Prevents Tubulointerstitial Fibrosis and Immune Activation in Diabetic Nephropathy in Mice.
Combined injection of pristane and Bacillus Calmette-Guerin Vaccine successfully establishes a lupus model with atherosclerosis.
Comprehensive profiling of cell type-specific expression and distribution of complement genes in mouse and human kidneys: insights into normal physiology and response to kidney transplantations.
The potential of taVNS in attenuating blood-brain barrier damage, promoting angiogenesis and improving impaired cognitive function in a rat model of vascular cognitive impairment and dementia by activating the Wnt7/β-catenin signaling pathway.
Dual mechanisms of Vitisin A in managing alcoholic liver disease: Inhibition of lipogenesis and complement activation.
Targeted modulation of intestinal barrier and mucosal immune-related microbiota attenuates IgA nephropathy progression.
Exploring the biological mechanisms of severe COVID-19 in the elderly: Insights from an aged mouse model.
SerpinA3N-APOE interaction in astrocytes exacerbates Alzheimer's disease progression through NFκB activation.
Regulatory T cells promote microglia-mediated synapse engulfment and functional recovery via the OPN-CD74 axis after spinal cord injury in mice.
Proteomic profiling reveals the molecular signatures of chemotherapy-induced human ovarian damage.
Scutellarin Modulates Astrocyte-Microglia-Neuron Crosstalk to Mitigate Neuroinflammation and Apoptosis in Cerebral Ischemia.
Complement Molecule C3a Exacerbates Early Brain Injury After Subarachnoid Hemorrhage by Inducing Neuroinflammation Through the C3aR-ERK-P2X7-NLRP3 Inflammasome Signaling Axis.
Neutrophils undergo migration and produce an antiviral response following porcine epidemic diarrhea virus infection.
Gut-derived bacterial vesicles carrying lipopolysaccharide promote microglia-mediated synaptic pruning.
CD81(+) senescent-like fibroblasts exaggerate inflammation and activate neutrophils via C3/C3aR1 axis in periodontitis.
Astrocyte-conditional knockout of MOB2 inhibits the phenotypic conversion of reactive astrocytes from A1 to A2 following spinal cord injury in mice.
Neuroimmune regulation of IFITM3 via γ-secretase in astrocytes during cerebral ischemia-reperfusion.
Guanxinning Tablet Alleviates Post-Ischemic Stroke Injury Via Regulating Complement and Coagulation Cascades Pathway and Inflammatory Network Mobilization.
M1 Microglia-Derived Exosomes Promote A1 Astrocyte Activation and Aggravate Ischemic Injury via circSTRN3/miR-331-5p/MAVS/NF-κB Pathway.
Myeloid Cell Trim59 Deficiency Worsens Experimental Ischemic Stroke and Alters Cerebral Proteomic Profile.
Exploring the effects of moxibustion on cognitive function in rats with multiple cerebral infarctions from the perspective of glial vascular unit repairing.
The m6A reader YTHDC2 promotes the pathophysiology of temporal lobe epilepsy by modulating SLC7A11-dependent glutamate dysregulation in astrocytes.
HIF Stabilizer Desidustat Protects against Complement-Mediated Diseases.
Exercise training upregulates CD55 to suppress complement-mediated synaptic phagocytosis in Parkinson's disease.
A bifunctional amylopullulanase of Streptococcus suis ApuA contributes to immune evasion by interaction with host complement C3b.
Vitexin attenuates neuropathic pain by regulating astrocyte autophagy flux and polarization via the S1P/ S1PR1-PI3K/ Akt axis.
Astrocytic purinergic signalling contributes to the development and maintenance of neuropathic pain via modulation of glutamate release.
Identification of disease-specific extracellular vesicle-associated plasma protein biomarkers for Duchenne Muscular Dystrophy and Facioscapulohumeral Muscular Dystrophy.
Ficolin-3 induces apoptosis and suppresses malignant property of hepatocellular carcinoma cells via the complement pathway.
Modulation of PKM2 inhibits follicular helper T cell differentiation and ameliorates inflammation in lupus-prone mice.
Cross-species single-cell analysis uncovers the immunopathological mechanisms associated with IgA nephropathy progression.
Effect of Myelin Debris on the Phenotypic Transformation of Astrocytes after Spinal Cord Injury in Rats.
Effect of total flavonoids of Dracocephalum moldavica L. On neuroinflammation in Alzheimer's disease model amyloid-β (Aβ1-42)-peptide-induced astrocyte activation.
Nuclear AGO2 promotes myocardial remodeling by activating ANKRD1 transcription in failing hearts.
Inhibition of aquaporin-4 and its subcellular localization attenuates below-level central neuropathic pain by regulating astrocyte activation in a rat spinal cord injury model.
Effectiveness of a novel rat model of off-target PLA2R1 knockout to renal impairment.
Extracellular vesicle biomarkers for complement dysfunction in schizophrenia.
Interior decorative volatile organic compounds exposure induces sleep disorders through aberrant branched chain amino acid transaminase 2 mediated glutamatergic signaling resulting from a neuroinflammatory cascade.
Activation of mitochondrial DNA-mediated cGAS-STING pathway contributes to chronic postsurgical pain by inducing type I interferons and A1 reactive astrocytes in the spinal cord.
Integrin β1-rich extracellular vesicles of kidney recruit Fn1+ macrophages to aggravate ischemia-reperfusion-induced inflammation.
Microplastics exposure induced and exacerbated the development of systemic lupus erythematosus in mice.
Targeting blood brain barrier-Remote ischemic conditioning alleviates cognitive impairment in female APP/PS1 rats.
Balancing macrophage polarization via stem cell-derived apoptotic bodies for diabetic wound healing.
Complement components regulates ferroptosis in CVB3 viral myocarditis by interatction with TFRC.
Effectiveness of a Novel PLA2R1 Knock-in Middle Age Rat Model in Repairing Renal Function Damage.
Human umbilical cord mesenchymal stem cells mitigate A1 astrocyte neuroinflammation induced by 1,2-dichloroethane via ERBB pathway inhibition.
Ponatinib exacerbate renal injury in systemic lupus erythematosus mouse model through PDGFR-PI3K/AKT pathway.
C3(+) cancer-associated fibroblasts promote tumor growth and therapeutic resistance in gastric cancer via activation of the NF-κB signaling pathway.
Blockade of OX40/OX40L signaling using anti-OX40L alleviates murine lupus nephritis.
A2 reactive astrocyte-derived exosomes alleviate cerebral ischemia-reperfusion injury by delivering miR-628.
Quercetin-loaded Human Umbilical cord Mesenchymal Stem Cell-derived sEVs for Spinal Cord Injury Recovery.
Study on the underlying molecular mechanism of benzene-induced nervous system damage in mice based on tandem mass tag (TMT) proteomics.
Enriched Environment Inhibits Neurotoxic Reactive Astrocytes via JAK2-STAT3 to Promote Glutamatergic Synaptogenesis and Cognitive Improvement in Chronic Cerebral Hypoperfusion Rats.
KYNA Ameliorates Glutamate Toxicity of HAND by Enhancing Glutamate Uptake in A2 Astrocytes.
Complement C1q-mediated microglial synaptic elimination by enhancing desialylation underlies sevoflurane-induced developmental neurotoxicity.
Effects of liraglutide on astrocyte polarization and neuroinflammation in db/db mice: focus on iron overload and oxidative stress.
TIGIT-Fc fusion protein alleviates murine lupus nephritis through the regulation of SPI-B-PAX5-XBP1 axis-mediated B-cell differentiation.
The Oxysterol Receptor EBI2 Links Innate and Adaptive Immunity to Limit IFN Response and Systemic Lupus Erythematosus.
Knockout of microglial Hv1 proton channel reduces neurotoxic A1 astrocytes and neuronal damage via the ROS/STAT3 pathway after spinal cord injury.
Cell-specific NFIA upregulation promotes epileptogenesis by TRPV4-mediated astrocyte reactivity.
Repurposing crizotinib to target RIPK1-dependent cell death.
Kynurenic acid blunts A1 astrocyte activation against neurodegeneration in HIV-associated neurocognitive disorders.
Unrecognized Potent Activities of Colistin Against Clinically Important mcr+ Enterobacteriaceae Revealed in Synergy with Host Immunity.
Proteomics and transcriptomics profiling reveals distinct aspects of kidney stone related genes in calculi rats.
Blocking Two-Pore Domain Potassium Channel TREK-1 Inhibits the Activation of A1-Like Reactive Astrocyte Through the NF-κB Signaling Pathway in a Rat Model of Major Depressive Disorder.
Autophagy enables microglia to engage amyloid plaques and prevents microglial senescence.
Therapeutic hyperthermia regulates complement C3 activation and suppresses tumor development through HSPA5/NFκB/CD55 pathway in nasopharyngeal carcinoma.
Tandem Mass Tag-based proteomics analysis reveals the vital role of inflammation in traumatic brain injury in a mouse model.
PPARγ Acetylation Orchestrates Adipose Plasticity and Metabolic Rhythms.
HIF-1α participates in secondary brain injury through regulating neuroinflammation.
Qihuang Granule protects the retinal pigment epithelium from oxidative stress via regulation of the alternative complement pathway.
Neuron-Derived Exosomes Promote the Recovery of Spinal Cord Injury by Modulating Nerve Cells in the Cellular Microenvironment of the Lesion Area.
Inhibition of acid sphingomyelinase reduces reactive astrocyte secretion of mitotoxic extracellular vesicles and improves Alzheimer's disease pathology in the 5xFAD mouse.
Hemocompatibility tuning of an innovative glutaraldehyde-free preparation strategy using riboflavin/UV crosslinking and electron irradiation of bovine pericardium for cardiac substitutes.
Integrated transcriptomics and metabolomics analysis reveals that C3 and C5 are vital targets of DuZhi Wan in protecting against cerebral ischemic injury.
SIRT3 alleviates mitochondrial dysfunction induced by recurrent low glucose and improves the supportive function of astrocytes to neurons.
Neutral Sphingomyelinase 2 Mediates Oxidative Stress Effects on Astrocyte Senescence and Synaptic Plasticity Transcripts.
Cyanidin-3-O-glucoside ameliorates cadmium induced uterine epithelium proliferation in mice.
Natural antibodies and CRP drive anaphylatoxin production by urate crystals.
1,25-dihydroxyvitamin D3 ameliorates lupus nephritis through inhibiting the NF-κB and MAPK signalling pathways in MRL/lpr mice.
Total coumarin derivates from Hydrangea paniculata attenuate renal injuries in cationized-BSA induced membranous nephropathy by inhibiting complement activation and interleukin 10-mediated interstitial fibrosis.
Pandemic Influenza Infection Promotes Streptococcus pneumoniae Infiltration, Necrotic Damage, and Proteomic Remodeling in the Heart.
Cornuside Is a Potential Agent against Alzheimer's Disease via Orchestration of Reactive Astrocytes.
Activation of C3 and C5 May Be Involved in the Inflammatory Progression of PCM and GM.
Sequence analysis and function of mosquito aeCCC2 and Drosophila Ncc83 orthologs.
Exogenous Biological Renal Support Improves Kidney Function in Mice With Rhabdomyolysis-Induced Acute Kidney Injury.
Proteomic Landscape of Exosomes Reveals the Functional Contributions of CD151 in Triple-Negative Breast Cancer.
Extracellular vesicles derived from CD73 modified human umbilical cord mesenchymal stem cells ameliorate inflammation after spinal cord injury.
Kinetic Multi-omic Analysis of Responses to SARS-CoV-2 Infection in a Model of Severe COVID-19.
Complement C3 Aggravates Post-epileptic Neuronal Injury Via Activation of TRPV1.
Cholecystokinin octapeptide improves hippocampal glutamatergic synaptogenesis and postoperative cognition by inhibiting induction of A1 reactive astrocytes in aged mice.
Adipsin promotes bone marrow adiposity by priming mesenchymal stem cells.
Silencing of circIgf1r plays a protective role in neuronal injury via regulating astrocyte polarization during epilepsy.
Yak milk-derived exosomes alleviate lipopolysaccharide-induced intestinal inflammation by inhibiting PI3K/AKT/C3 pathway activation.
Increased circulating levels of Factor H-Related Protein 4 are strongly associated with age-related macular degeneration.
C-reactive protein (CRP) recognizes uric acid crystals and recruits proteases C1 and MASP1.
The Surface-Exposed Protein SntA Contributes to Complement Evasion in Zoonotic Streptococcus suis.
4-Hydroxy-7-oxo-5-heptenoic Acid Lactone Is a Potent Inducer of the Complement Pathway in Human Retinal Pigmented Epithelial Cells.
Differential protein analysis of serum exosomes post-intravenous immunoglobulin therapy in patients with Kawasaki disease.
Generation of complement protein C3 deficient pigs by CRISPR/Cas9-mediated gene targeting.
Serum estradiol levels in controlled ovarian stimulation directly affect the endometrium.
Identification of Potential Biomarkers for Rhegmatogenous Retinal Detachment Associated with Choroidal Detachment by Vitreous iTRAQ-Based Proteomic Profiling.
Zhao Z, Duan X, Huang H, Zhang Y, Wang M, Qin J, Lin S, Chen H
Glia 2026 May;74(5):e70148
Glia 2026 May;74(5):e70148
Time-dependent neuroprotective effects of YL-IPA08 in repetitive mild traumatic brain injury associated with changes in Caprin1/SHH signaling.
Yu C, Ye Q, Song Z, Li J, Li Z, Wang Z, Wang J, Li H, Li Y, Ouyang W
European journal of pharmacology 2026 May 10;1023:178868
European journal of pharmacology 2026 May 10;1023:178868
ACSL4-mediated astrocyte ferroptosis augments neuroinflammation and exacerbates NMOSD pathology.
Wen H, Zi Y, Liu Z, Bai Y, Lin J, Wang H, Xu B, Wang J, Wang H
Cell death and differentiation 2026 Mar 3;
Cell death and differentiation 2026 Mar 3;
Ovarian Matrisome Dynamics and αvβ3-Mediated Regulation in Early Follicular Development.
Wu T, Feng Y, Zhu Q, Jiang T, Gao Y, Nie K, Tang X, Chen Y, Hu D, Yang X, Wang S, Wu M, Zhang J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 14;:e07314
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 14;:e07314
Astrocyte-Specific Nrf2 Expression Transforms Neurotoxic Reactive Astrocytes to Neuroprotective Phenotype in 3xTg-AD Mice.
Guo S, Wei F, Sun H, Jin H, Cheng W, Fu C, Wang H, Yin Y
Glia 2026 Jan;74(1):e70087
Glia 2026 Jan;74(1):e70087
MAFG Induces the Methylation of CRYAB to Promote the Activation of A1 Astrocyte After Spinal Cord Injury.
Li X, Zhu Z, Wang Y, Wan H, Wang Z, Qiao W
Immunity, inflammation and disease 2026 Jan;14(1):e70334
Immunity, inflammation and disease 2026 Jan;14(1):e70334
Fecal microbiota transplantation promotes Wnt3a-mediated hippocampal neurogenesis in a rat model of chronic cerebral hypoperfusion.
Su SH, Lu DD, Wu YF, Huang XS, Zhang L
Journal of translational medicine 2026 Jan 22;24(1):109
Journal of translational medicine 2026 Jan 22;24(1):109
Comprehensive Transcriptomic Profiling Reveals Rotavirus-Induced Alterations in Both Coding and Long Non-Coding RNA Expression in MA104 Cells.
Song X, Wu Y, Yin X, Hu X, Wu J, Kuang X, Chen R, Lin X, Ye J, Zhang G, Sun M, Zhou Y, Li H
Viruses 2026 Jan 20;18(1)
Viruses 2026 Jan 20;18(1)
Integrated Profiling of DEHP-Induced Hippocampal Neurotoxicity in Adult Female Rats Based on Transcriptomic and Neurobiological Analyses.
Bai J, Li J, Tang L, Sun W, Gao F, Zhang X, Bian R, Wang R
Toxics 2026 Jan 14;14(1)
Toxics 2026 Jan 14;14(1)
C5aR1(+) microglia exacerbate neuroinflammation and cerebral edema in acute brain injury.
Zhou J, Ma S, Feng D, Tian Y, Li L, Guo H, Shi Y, Cui W, Dong J, Hao S, Guo C, Xu M, Han L, Bai H, He D, Cui X, Chen L, Wu X, Gao F, Hu Q, Zhang Z, Wang K, Zhou G, Feng T, Xue D, Lin Q, Wang L, Gao L, Heng L, Zhao T, Luo T, Tian B, Zhang X, Guo W, Li Z, Liu H, Ge S, Liu Q, Qu Y
Neuron 2026 Feb 4;114(3):444-462.e9
Neuron 2026 Feb 4;114(3):444-462.e9
Helicobacter pylori-Induced Inflammatory Cancer Transformation Microenvironment Drives Gastric Carcinogenesis.
Fu Y, Tong J, Zhu M, Xu L, Huang F, Zhang Y, Wang X, Wang Z, Zhang J, Lv J, Jiang T, Lv B, Zhang G
Cellular and molecular gastroenterology and hepatology 2026 Feb 26;20(7):101757
Cellular and molecular gastroenterology and hepatology 2026 Feb 26;20(7):101757
Tocilizumab-loaded nanoparticles block IL-6R and reduce edema after intracerebral hemorrhage.
Ma S, Lin Q, Xue D, Li L, Liu H, Guo H, Sun F, Dong J, Guo C, Han L, Zhao J, Ma J, Wang Q, Guo W, Ge S, Tian Y, Zhou J, Qu Y
Journal of advanced research 2026 Feb 16;
Journal of advanced research 2026 Feb 16;
Wzi modulates immune evasion of hypervirulent Klebsiella pneumoniae in a CPS-dependent and independent manner.
Wei S, Xu T, Xiang Q, Liu J, Li D, Zhang J, Huang L, Liu J, Liu J, Chen Y, Du Q, Zhou K
Virulence 2026 Dec;17(1):2656049
Virulence 2026 Dec;17(1):2656049
Gut microbial ammonia as a mediator of PFOS neurotoxicity and its remediation by the flavonoid Icaritin.
Yi Y, Zhang W, Wei Y, Ran W, Liu D, Deng W, Duan S, Yao J, Wang L, Zhang Y, Gao J, Gong Q
Gut microbes 2026 Dec 31;18(1):2620125
Gut microbes 2026 Dec 31;18(1):2620125
YAP Regulates Microglial Anti-Inflammatory Responses and Alleviates Cognitive Impairment Through the IL-33/ST2 Pathway after Traumatic Brain Injury.
Zhao R, Gao SQ, Wang X, Li T, Gao CC, Han YL, Qiu JY, Miao SH, Sun Y, Zheng XB, Jin WX, Zhou ML
Journal of neurotrauma 2026 Apr;43(7-8):641-659
Journal of neurotrauma 2026 Apr;43(7-8):641-659
Polydopamine-Encapsulated Probiotics Restore Gut Homeostasis and Reinstate Macrophage Efferocytosis in Systemic Lupus Erythematosus.
Wu R, Liu M, Gao C, Zhao C, Zhao F, Dong S, Zhang B, Liu Q, Zhang W, Zhao M, Lu Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(24):e22637
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(24):e22637
Deciphering Apolipoprotein A4 in the Protein Corona of Ligand-Modified Liposomes for Tumor Targeting and Penetration.
Liang Y, Li X, Zhang Y, Ding X, Nie W, Wang S, Huang M, Wu Y, Wu S, Zhao X, Li Y, Zhang Z
ACS nano 2026 Apr 21;20(15):11673-11691
ACS nano 2026 Apr 21;20(15):11673-11691
Xuming tongmai decoction modulates astrocyte polarization and mitophagy via the PINK1/Parkin pathway in a rat model of acute ischemic stroke.
Ran L, Lan X, Zeng Z, Yu X, Yang R, Tang J
Brain research 2026 Apr 15;1877-1878:150203
Brain research 2026 Apr 15;1877-1878:150203
Biosynthesis of Lysosomally Escaped Apoptotic Bodies Inhibits Inflammasome Synthesis in Macrophages.
Mao J, Xia W, Wu Y, Li M, Zhao Y, Zhai P, Zhang Y, Zan T, Cui W, Sun X
Research (Washington, D.C.) 2025;8:0581
Research (Washington, D.C.) 2025;8:0581
Vincristine Regulates C/EBP-β/TGF-β1 to Promote A1 Astrocyte Polarization and Induce Neuropathic Pain.
Chen Y, Tang G, Lu J, Tang S, Xiong X, Chen C, Pei L, Shi J
Drug design, development and therapy 2025;19:827-840
Drug design, development and therapy 2025;19:827-840
Cholecystokinin ameliorates cognitive impairment via inhibiting microglia phagocytosis of excitatory synapses in sepsis-associated encephalopathy mice.
Chen L, Li Z, Gao Y, Piao G, Li Y, Hong J, Wang Q, Liu K, Wang J, Du A, Chen L, Guo X, Li Z, Liu T
Journal of neuroinflammation 2025 Sep 29;22(1):217
Journal of neuroinflammation 2025 Sep 29;22(1):217
Penthorum chinense Pursh extract ameliorates lupus nephritis disease in MRL/lpr mice via the PPARγ/NFκB signaling axis.
Li Y, Hua Y, Xin X, He W, Xu L, Ding B, Huang Q, Fan Y, Tian F, Ji J
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120379
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120379
Echinacoside targets the HIF-1α/LDHA axis to modulate A1/A2 astrocyte differentiation and promote glial scar repair following ischemic stroke.
Liao Y, Yang L, Guo C, Hu J, Wen L, Ju B, Hou Q, Zhu H, Ding Y, Yang J, Zhao M
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120375
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120375
Transcription factor RUNX2 participates in astrocyte-mediated neuropathic pain via transcriptional activation of Ccl2.
Shen W, Song S, Zhao X, Li D, Liu J, Yue S
Biochemical and biophysical research communications 2025 Sep 1;777:152263
Biochemical and biophysical research communications 2025 Sep 1;777:152263
Microglia in the Rostral Ventromedial Medulla Mediate Synaptic Pruning via the C1q/C3-CR3 Signaling Pathway-A Mechanism for the Chronic Orofacial Pain.
Huang X, Zeng J, Hu Z, Wu Y, Zhang G, Zhang C, Yu C, Song M
Molecular neurobiology 2025 Oct;62(10):13338-13351
Molecular neurobiology 2025 Oct;62(10):13338-13351
Rutin ameliorates sevoflurane-induced neurotoxicity by inhibiting microglial synaptic phagocytosis through the complement pathway.
Tian X, Xiong M, Jiang Z, Hong R, Wang H
Scientific reports 2025 Oct 30;15(1):38077
Scientific reports 2025 Oct 30;15(1):38077
Activation of the C3 Complement Pathway in the Hippocampus Produces Anxiodepressive Effects in a Mouse Model of Inflammation Pain.
Zhang A, Zhang X, Tang X, Liu M, Xie J, Li S, Cao W, Zhou H, Xu Y
Molecular neurobiology 2025 Nov;62(11):14032-14049
Molecular neurobiology 2025 Nov;62(11):14032-14049
hADMSC-Evs attenuates depressive and anxiety - like behaviors in chronic liver disease via suppressing Liver-Brain Galectin3 signaling.
Fu W, Guo Y, Wu P, Xiao L, Qi W, Cao H, Dong N, Zhao RC, Wang J
Brain, behavior, and immunity 2025 Nov;130:106082
Brain, behavior, and immunity 2025 Nov;130:106082
Microglial activation drives neuronal dysregulation in alcohol-induced seizure susceptibility.
Zhang S, Zhou Y, Ren Y, Shang J, Jiang A, Hong Y, Hong S, Wang C, Wang W, Chen J
Scientific reports 2025 Nov 3;15(1):38389
Scientific reports 2025 Nov 3;15(1):38389
A1-Reactive Astrocytes in the Posterior Part of Paraventricular Thalamic Nucleus Are Involved in Pain Modulation in Mice.
Sun HX, Liu ZY, Li JN, Zhao LJ, Wu XM, Liu CH, Hong J, Zhu KH, Wu FL, Chen SH, Dong YL, Li YQ
Molecular neurobiology 2025 Nov 29;63(1):209
Molecular neurobiology 2025 Nov 29;63(1):209
Aspirin Attenuates the Pathogenesis of Amyotrophic Lateral Sclerosis by Inhibiting the Activities of Microglia in a NF-κB-dependent Complement System-deactivating Mechanism.
Ge TQ, Ma XY, Guan PP, Wang P
Molecular neurobiology 2025 Nov 26;63(1):180
Molecular neurobiology 2025 Nov 26;63(1):180
GRP78 alleviates secondary brain injury by regulating phenotype polarization in astrocytes via JAK2-STAT3 pathway after intracerebral hemorrhage.
Yang J, Duan C, Song Y, Zhu X, Shen J, Ji Q
International immunopharmacology 2025 Nov 14;165:115466
International immunopharmacology 2025 Nov 14;165:115466
Electroacupuncture Alleviates Cerebral Ischemia-Reperfusion Injury by Downregulating IL-17 A and Inhibiting Neurotoxic Astrocyte Activation.
Zhao MM, Song Q, Xie QY, Sun WQ, Zhang Y, Tang W, Li MX
Neurochemical research 2025 Nov 10;50(6):355
Neurochemical research 2025 Nov 10;50(6):355
Potentiated fractalkine signaling axis affects neuroinflammation in 1,2-dichloroethane- intoxicated mice via divergent modulating ways on microglial hyperactivation.
Yang J, Yang J, Hu H, Jiang W, Zhang X, Wang G, Zhao F, Liao Y, Jin Y
Ecotoxicology and environmental safety 2025 Nov 1;306:119322
Ecotoxicology and environmental safety 2025 Nov 1;306:119322
Xixin Decoction May Treat Vascular Dementia by Modulating the NPTX2/C1q/C3 Complement Pathway.
Yang S, Gao XQ, Tan AH, Ge P
Chemistry & biodiversity 2025 May;22(5):e202402208
Chemistry & biodiversity 2025 May;22(5):e202402208
PDE4 inhibition alleviates HMGB1/C1q/C3-mediated excessive phagocytic pruning of synapses by microglia and depressive-like behaviors in mice.
Zhao Q, Zeng C, Luo F, Xian Z, Wen H, Tu X, Yang R, Sun Y, Zheng X, Xu J, Wang H
Brain, behavior, and immunity 2025 May;126:126-143
Brain, behavior, and immunity 2025 May;126:126-143
Microbiota-Derived Inosine Suppresses Systemic Autoimmunity via Restriction of B Cell Differentiation and Migration.
Gao L, Zhang Y, Hu Z, Chen S, Wang Q, Zeng Y, Yin H, Zhao J, Zhan Y, Gao C, Xin Y, Chen B, van der Veen S, Zhao M, Fang D, Lu Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(20):e2409837
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(20):e2409837
Ficolin-3 Activates Complement and Triggers Necroptosis in Cholangiocarcinoma Cells via the RIPK1/RIPK3/MLKL Signaling Pathway.
Zhang Z, Yin M, Geng X, Zhao H, Zhang S, Liu Y, Liang Y, Ji J, Zheng G
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70673
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70673
Capsazepine Inhibits Astrocyte Activation and Attenuates Neuroinflammation by Targeting Syntaxin 7.
Hou Y, Yang Y, Zhao Z, Wang S, Chen X, Xie Y, Chen H, Xu J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70657
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70657
Inhibition of S100A4 decreases neurotoxic astrocyte reactivity and attenuates neuropathic pain via the TLR4/NF-κB pathway in a rat model of spinal nerve ligation.
Xue T, Song Y, Zhao J, Fan G, Liu Z
The journal of headache and pain 2025 May 1;26(1):97
The journal of headache and pain 2025 May 1;26(1):97
Therapeutic effect of pH responsive Magainin II modified azithromycin plus curcumin micelles in different depth models of MRSA infection.
Zhang L, Guo RB, Liu Y, Kong L, Zang J, Zhang ZX, Wang JH, Chen MH, Liu M, Yu Y, Li XT
Scientific reports 2025 Mar 3;15(1):7383
Scientific reports 2025 Mar 3;15(1):7383
TNF-α mediates activation of neuronal necroptotic signaling in rat with syringomyelia.
Li J, Cui S, Li Y, Bai J, Zhang C, Li K, Jian F
Experimental neurology 2025 Jun;388:115214
Experimental neurology 2025 Jun;388:115214
Astragalin-functionalized ultrasmall nanoparticles modulate the complement pathway to inhibit microglial synaptic phagocytosis for reducing anesthetic neurotoxicity.
Wang G, Han Y, Peng K, Jiang Z, Wang T, Zheng Q, Li W, Xu H, Ji F, Li Z
Materials today. Bio 2025 Jun;32:101714
Materials today. Bio 2025 Jun;32:101714
Acupuncture regulates astrocyte neurotoxic polarization to protect blood-brain barrier integrity in delayed thrombolysis through mediating ERK1/2/Cx43 axis.
Zhang ZH, Gu Y, Huang Z, Liu XY, Xu WT, Zhang XC, Ni GX
IBRO neuroscience reports 2025 Jun;18:604-618
IBRO neuroscience reports 2025 Jun;18:604-618
Multi-omics analysis reveals metabolic disruptions in cardiac tissues of aging nonhuman primates with spontaneous type 2 diabetes.
Liu Y, Yu J, Hu H, Pu S, Wu H, Ma Y, Yang W, Fang C, Sun F, Wang H
Aging 2025 Jun 2;17(6):1386-1404
Aging 2025 Jun 2;17(6):1386-1404
Colistin exerts potent activity against mcr+ Enterobacteriaceae via synergistic interactions with the host defense.
Kumaraswamy M, Riestra AM, Flores A, Dahesh S, Askarian F, Uchiyama S, Monk J, Jung S, Bondsäter G, Nilsson V, Chang M, Bulitta JB, Lang Y, Kousha A, Bjånes E, Chavarria N, Clark T, Seo H, Sakoulas G, Nizet V
The Journal of clinical investigation 2025 Jun 16;135(12)
The Journal of clinical investigation 2025 Jun 16;135(12)
GABA-dependent microglial elimination of inhibitory synapses underlies neuronal hyperexcitability in epilepsy.
Chen ZP, Zhao X, Wang S, Cai R, Liu Q, Ye H, Wang MJ, Peng SY, Xue WX, Zhang YX, Li W, Tang H, Huang T, Zhang Q, Li L, Gao L, Zhou H, Hang C, Zhu JN, Li X, Liu X, Cong Q, Yan C
Nature neuroscience 2025 Jul;28(7):1404-1417
Nature neuroscience 2025 Jul;28(7):1404-1417
A novel IgD-FcδR blocker, IgD-Fc-Ig fusion protein, effectively alleviates abnormal activation of T cells the disease progression in systemic lupus erythematosus.
He J, Liu D, Jiang L, Chen M, Ling X, Dong M, Wu T, Guo T, Xu N, Zhang J, Li T, Wang Y, Zhao J, Wei W, Yan S, Wu Y
Biochemical pharmacology 2025 Jul;237:116930
Biochemical pharmacology 2025 Jul;237:116930
Effectiveness of a Novel PLA2R1 Knock-In Rat Model in Repairing Renal Function Damage.
Huang B, Sui WD, Zhang ZT, Zhao L, Li YY, Yang DH, Zhou Y
Journal of biochemical and molecular toxicology 2025 Jan;39(1):e70056
Journal of biochemical and molecular toxicology 2025 Jan;39(1):e70056
C3/C3aR Bridges Spinal Astrocyte-Microglia Crosstalk and Accelerates Neuroinflammation in Morphine-Tolerant Rats.
Peng X, Ju J, Li Z, Liu J, Jia X, Wang J, Ren J, Gao F
CNS neuroscience & therapeutics 2025 Jan;31(1):e70216
CNS neuroscience & therapeutics 2025 Jan;31(1):e70216
Tracking astrocyte polarization in the retina in retinopathy of prematurity.
Feng X, Zhang L, Jiao K, Li Y, Wu M, Xie Y, Xiao L
Experimental eye research 2025 Jan;250:110170
Experimental eye research 2025 Jan;250:110170
Astrocyte-neuron communication through the complement C3-C3aR pathway in Parkinson's disease.
Chi X, Yin S, Sun Y, Kou L, Zou W, Wang Y, Jin Z, Wang T, Xia Y
Brain, behavior, and immunity 2025 Jan;123:229-243
Brain, behavior, and immunity 2025 Jan;123:229-243
Therapeutic potential of simvastatin in ALS: Enhanced axonal integrity and motor neuron survival through Apoa4 and Alb modulation.
Luo S, Wang X, Ma B, Liu D, Li L, Wang L, Ding N, Zou L, Wang J, Pan J, Sang D, Zhou H, Qu H, Lu Y, Yang L
Biomolecules & biomedicine 2025 Jan 30;25(3):632-647
Biomolecules & biomedicine 2025 Jan 30;25(3):632-647
TDP43 augments astrocyte inflammatory activity through mtDNA-cGAS-STING axis in NMOSD.
Liu Z, Bai Y, Xu B, Wen H, Chen K, Lin J, Wang Y, Xu J, Wang H, Shi F, Wang J, Wang H
Journal of neuroinflammation 2025 Jan 22;22(1):14
Journal of neuroinflammation 2025 Jan 22;22(1):14
Glucosyl Hesperidin Supplementation Prevents Tubulointerstitial Fibrosis and Immune Activation in Diabetic Nephropathy in Mice.
Hashimoto K, Yoshida Y, Kamesawa M, Yazawa N, Tominaga H, Aisyah R, Chen S, Bumrungkit C, Kawamoto S, Kumrungsee T, Yanaka N
Nutrients 2025 Jan 21;17(3)
Nutrients 2025 Jan 21;17(3)
Combined injection of pristane and Bacillus Calmette-Guerin Vaccine successfully establishes a lupus model with atherosclerosis.
Jiang C, Zhu Z, Tai Y, Lu M, Cheng H, Su T, Guo P, Fang R, He F, Ge M, Guan Q, Han Y, Yan S, Wei W, Wang Q
Experimental cell research 2025 Jan 15;444(2):114381
Experimental cell research 2025 Jan 15;444(2):114381
Comprehensive profiling of cell type-specific expression and distribution of complement genes in mouse and human kidneys: insights into normal physiology and response to kidney transplantations.
Li X, Zhu L
Renal failure 2025 Dec;47(1):2471568
Renal failure 2025 Dec;47(1):2471568
The potential of taVNS in attenuating blood-brain barrier damage, promoting angiogenesis and improving impaired cognitive function in a rat model of vascular cognitive impairment and dementia by activating the Wnt7/β-catenin signaling pathway.
Sun R, Li H, Wang M, Yan L, Jiang J, Liu Q, Li S, Liang Y, Qian Y, Yu T
Autonomic neuroscience : basic & clinical 2025 Dec;262:103353
Autonomic neuroscience : basic & clinical 2025 Dec;262:103353
Dual mechanisms of Vitisin A in managing alcoholic liver disease: Inhibition of lipogenesis and complement activation.
Zhu Y, Deng H, Liu J, Li X, Huang X, Che Z, Bai W, Jiao R
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Dec;206:115639
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Dec;206:115639
Targeted modulation of intestinal barrier and mucosal immune-related microbiota attenuates IgA nephropathy progression.
Zhang R, Tang Y, Feng X, Lu X, Zhao M, Jin J, Ji X, He H, Zhao L
Gut microbes 2025 Dec;17(1):2458184
Gut microbes 2025 Dec;17(1):2458184
Exploring the biological mechanisms of severe COVID-19 in the elderly: Insights from an aged mouse model.
Ma L, Lin X, Xu M, Ke X, Liu D, Chen Q
Virulence 2025 Dec;16(1):2487671
Virulence 2025 Dec;16(1):2487671
SerpinA3N-APOE interaction in astrocytes exacerbates Alzheimer's disease progression through NFκB activation.
Liu C, Xu S, Yao H, Wang Y, Liu Q, Zhou H, Luo Y, Li X, Li S, Li C
Journal of neuroinflammation 2025 Dec 4;23(1):8
Journal of neuroinflammation 2025 Dec 4;23(1):8
Regulatory T cells promote microglia-mediated synapse engulfment and functional recovery via the OPN-CD74 axis after spinal cord injury in mice.
Liu R, Yan H, Liu X, Xie Y, Li Y, Wang Z, Huang H, Yu Z, Qu W, Wang M, Luo X
Journal of neuroinflammation 2025 Dec 15;23(1):21
Journal of neuroinflammation 2025 Dec 15;23(1):21
Proteomic profiling reveals the molecular signatures of chemotherapy-induced human ovarian damage.
Grosbois J, Bisteau X, Imbault V, Conrard L, Condorelli M, Findikli N, Lybaert P, Demeestere I
Human reproduction (Oxford, England) 2025 Dec 1;40(12):2395-2408
Human reproduction (Oxford, England) 2025 Dec 1;40(12):2395-2408
Scutellarin Modulates Astrocyte-Microglia-Neuron Crosstalk to Mitigate Neuroinflammation and Apoptosis in Cerebral Ischemia.
Chen H, Duan Z, Jia Q, Zhang X, Xu D, Zheng L, Qi Z, Yang Y, Yang L, Wu C
Molecular neurobiology 2025 Aug;62(8):10834-10855
Molecular neurobiology 2025 Aug;62(8):10834-10855
Complement Molecule C3a Exacerbates Early Brain Injury After Subarachnoid Hemorrhage by Inducing Neuroinflammation Through the C3aR-ERK-P2X7-NLRP3 Inflammasome Signaling Axis.
Ming Y, Zhao P, Zhang H, Zhang Z, Huang Z, Zhang L, Sun Y, Li X
Inflammation 2025 Aug;48(4):1791-1810
Inflammation 2025 Aug;48(4):1791-1810
Neutrophils undergo migration and produce an antiviral response following porcine epidemic diarrhea virus infection.
Ma Y, Qin X, Zheng J, Peng X, Liu S, Lin R, Meng B, Cui X, Yang Q
Veterinary microbiology 2025 Aug;307:110605
Veterinary microbiology 2025 Aug;307:110605
Gut-derived bacterial vesicles carrying lipopolysaccharide promote microglia-mediated synaptic pruning.
Zhao X, Yu J, Xu B, Xu Z, Lei X, Han S, Luo S, Zhang C, Peng G, Li J, Yu J, Ling Y, Fan Z, Mo W, Yang Y, Zhang J
Alzheimer's & dementia : the journal of the Alzheimer's Association 2025 Aug;21(8):e70331
Alzheimer's & dementia : the journal of the Alzheimer's Association 2025 Aug;21(8):e70331
CD81(+) senescent-like fibroblasts exaggerate inflammation and activate neutrophils via C3/C3aR1 axis in periodontitis.
Fu L, Yin C, Zhao Q, Guo S, Shao W, Xia T, Sun Q, Chen L, Li J, Wang M, Xia H
eLife 2025 Aug 13;13
eLife 2025 Aug 13;13
Astrocyte-conditional knockout of MOB2 inhibits the phenotypic conversion of reactive astrocytes from A1 to A2 following spinal cord injury in mice.
Tao X, Chen H, Zhu Z, Ren T, Zhen H, Sun X, Song Y, Xu X, Song Z, Liu J
International journal of biological macromolecules 2025 Apr;300:140289
International journal of biological macromolecules 2025 Apr;300:140289
Neuroimmune regulation of IFITM3 via γ-secretase in astrocytes during cerebral ischemia-reperfusion.
Ni X, Pan Y, Liu X, Zhu Y, Yao X, Mo Y, Dai Q, Wang J
Biochimica et biophysica acta. Molecular basis of disease 2025 Apr;1871(4):167733
Biochimica et biophysica acta. Molecular basis of disease 2025 Apr;1871(4):167733
Guanxinning Tablet Alleviates Post-Ischemic Stroke Injury Via Regulating Complement and Coagulation Cascades Pathway and Inflammatory Network Mobilization.
Wang Y, Li Y, Zhou Y, Gao Y, Zhao L
Drug design, development and therapy 2024;18:4183-4202
Drug design, development and therapy 2024;18:4183-4202
M1 Microglia-Derived Exosomes Promote A1 Astrocyte Activation and Aggravate Ischemic Injury via circSTRN3/miR-331-5p/MAVS/NF-κB Pathway.
Li Z, Xu P, Deng Y, Duan R, Peng Q, Wang S, Xu Z, Hong Y, Zhang Y
Journal of inflammation research 2024;17:9285-9305
Journal of inflammation research 2024;17:9285-9305
Myeloid Cell Trim59 Deficiency Worsens Experimental Ischemic Stroke and Alters Cerebral Proteomic Profile.
Li X, Pan M, Tian X, Yang LZ, Zhang J, Yan D, Xu B, Zhao L, Fang W
Journal of inflammation research 2024;17:4827-4843
Journal of inflammation research 2024;17:4827-4843
Exploring the effects of moxibustion on cognitive function in rats with multiple cerebral infarctions from the perspective of glial vascular unit repairing.
Wang J, Du K, Liu C, Chen X, Ban W, Zhu G, Yang J
Frontiers in pharmacology 2024;15:1428907
Frontiers in pharmacology 2024;15:1428907
The m6A reader YTHDC2 promotes the pathophysiology of temporal lobe epilepsy by modulating SLC7A11-dependent glutamate dysregulation in astrocytes.
Zhang K, Yang Z, Yang Z, Du L, Zhou Y, Fu S, Wang X, Li X, Liu D, He X
Theranostics 2024;14(14):5551-5570
Theranostics 2024;14(14):5551-5570
HIF Stabilizer Desidustat Protects against Complement-Mediated Diseases.
Patel VJ, Joharapurkar AA, Kshirsagar SG, Patel MS, Savsani HH, Dodiya HS, Rakhasiya MH, Patel AK, Sundar R, Jain MR
Drug research 2024 Sep;74(7):325-334
Drug research 2024 Sep;74(7):325-334
Exercise training upregulates CD55 to suppress complement-mediated synaptic phagocytosis in Parkinson's disease.
Yao H, Tong W, Song Y, Li R, Xiang X, Cheng W, Zhou Y, He Y, Yang Y, Liu Y, Li S, Jin L
Journal of neuroinflammation 2024 Sep 28;21(1):246
Journal of neuroinflammation 2024 Sep 28;21(1):246
A bifunctional amylopullulanase of Streptococcus suis ApuA contributes to immune evasion by interaction with host complement C3b.
Xu J, Zhu J, Han W, Pang S, Deng S, Chen L, Chen X, Huang Q, Zhou R, Li L
Veterinary microbiology 2024 Oct;297:110212
Veterinary microbiology 2024 Oct;297:110212
Vitexin attenuates neuropathic pain by regulating astrocyte autophagy flux and polarization via the S1P/ S1PR1-PI3K/ Akt axis.
Huang K, Ding R, Lai C, Wang H, Fan X, Chu Y, Fang Y, Hua T, Yuan H
European journal of pharmacology 2024 Oct 15;981:176848
European journal of pharmacology 2024 Oct 15;981:176848
Astrocytic purinergic signalling contributes to the development and maintenance of neuropathic pain via modulation of glutamate release.
Liu S, Cheng H, Cui L, Jin L, Li Y, Zhu C, Ji Q, Tang J
Journal of neurochemistry 2024 Nov;168(11):3727-3744
Journal of neurochemistry 2024 Nov;168(11):3727-3744
Identification of disease-specific extracellular vesicle-associated plasma protein biomarkers for Duchenne Muscular Dystrophy and Facioscapulohumeral Muscular Dystrophy.
Bayazit MB, Henderson D, Nguyen KT, Reátegui E, Tawil R, Flanigan KM, Harper SQ, Saad NY
medRxiv : the preprint server for health sciences 2024 Nov 30;
medRxiv : the preprint server for health sciences 2024 Nov 30;
Ficolin-3 induces apoptosis and suppresses malignant property of hepatocellular carcinoma cells via the complement pathway.
Zheng G, Wu L, Bouamar H, Cserhati M, Chiu YC, Hinck CS, Wieteska Ł, Zeballos Torrez CR, Hu R, Easley A, Chen Y, Hinck AP, Cigarroa FG, Sun LZ
Life sciences 2024 Nov 15;357:123103
Life sciences 2024 Nov 15;357:123103
Modulation of PKM2 inhibits follicular helper T cell differentiation and ameliorates inflammation in lupus-prone mice.
Lin M, Huang L, Huang J, Yu J, Yang X, Yang J
Journal of autoimmunity 2024 May;145:103198
Journal of autoimmunity 2024 May;145:103198
Cross-species single-cell analysis uncovers the immunopathological mechanisms associated with IgA nephropathy progression.
Chen X, Wang T, Chen L, Zhao Y, Deng Y, Shen W, Li L, Yin Z, Zhang C, Cai G, Zhang M, Chen X
JCI insight 2024 May 8;9(9)
JCI insight 2024 May 8;9(9)
Effect of Myelin Debris on the Phenotypic Transformation of Astrocytes after Spinal Cord Injury in Rats.
Lv J, Yu H, Shan F, Ye J, Li A, Jing J, Zheng M, Tian D
Neuroscience 2024 May 24;547:1-16
Neuroscience 2024 May 24;547:1-16
Effect of total flavonoids of Dracocephalum moldavica L. On neuroinflammation in Alzheimer's disease model amyloid-β (Aβ1-42)-peptide-induced astrocyte activation.
Ren W, Yan XS, Fan JC, Huo DS, Wang XX, Jia JX, Yang ZJ
Journal of toxicology and environmental health. Part A 2024 May 18;87(10):436-447
Journal of toxicology and environmental health. Part A 2024 May 18;87(10):436-447
Nuclear AGO2 promotes myocardial remodeling by activating ANKRD1 transcription in failing hearts.
Xie R, Yuan S, Hu G, Zhan J, Jin K, Tang Y, Fan J, Zhao Y, Wang F, Chen C, Wang DW, Li H
Molecular therapy : the journal of the American Society of Gene Therapy 2024 May 1;32(5):1578-1594
Molecular therapy : the journal of the American Society of Gene Therapy 2024 May 1;32(5):1578-1594
Inhibition of aquaporin-4 and its subcellular localization attenuates below-level central neuropathic pain by regulating astrocyte activation in a rat spinal cord injury model.
Song Y, Xue T, Guo S, Yu Z, Yun C, Zhao J, Song Z, Liu Z
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2024 Mar;21(2):e00306
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2024 Mar;21(2):e00306
Effectiveness of a novel rat model of off-target PLA2R1 knockout to renal impairment.
Huang B, Zhang Z, Sui W, Zhao L, Li Y, Feng L, Yang D, Zhou Y
Genomics 2024 Mar;116(2):110796
Genomics 2024 Mar;116(2):110796
Extracellular vesicle biomarkers for complement dysfunction in schizophrenia.
Xue T, Liu W, Wang L, Shi Y, Hu Y, Yang J, Li G, Huang H, Cui D
Brain : a journal of neurology 2024 Mar 1;147(3):1075-1086
Brain : a journal of neurology 2024 Mar 1;147(3):1075-1086
Interior decorative volatile organic compounds exposure induces sleep disorders through aberrant branched chain amino acid transaminase 2 mediated glutamatergic signaling resulting from a neuroinflammatory cascade.
Zheng J, Wu M, Pang Y, Liu Q, Liu Y, Jin X, Tang J, Bao L, Niu Y, Zheng Y, Zhang R
The Science of the total environment 2024 Jul 15;934:173254
The Science of the total environment 2024 Jul 15;934:173254
Activation of mitochondrial DNA-mediated cGAS-STING pathway contributes to chronic postsurgical pain by inducing type I interferons and A1 reactive astrocytes in the spinal cord.
Chen Y, Hu Y, He X, Zang H, Sun R, Zhu C, Yao W
International immunopharmacology 2024 Jan 25;127:111348
International immunopharmacology 2024 Jan 25;127:111348
Integrin β1-rich extracellular vesicles of kidney recruit Fn1+ macrophages to aggravate ischemia-reperfusion-induced inflammation.
Wang W, Ren X, Chen X, Hong Q, Cai G
JCI insight 2024 Jan 23;9(2)
JCI insight 2024 Jan 23;9(2)
Microplastics exposure induced and exacerbated the development of systemic lupus erythematosus in mice.
Chen H, Wan L, Qiu Y, Qiu F, Wen C, Mao Y, He Z
The Science of the total environment 2024 Jan 20;909:168586
The Science of the total environment 2024 Jan 20;909:168586
Targeting blood brain barrier-Remote ischemic conditioning alleviates cognitive impairment in female APP/PS1 rats.
Ma Y, Sun W, Bai J, Gao F, Ma H, Liu H, Hu J, Xu C, Zhang X, Liu Z, Yuan T, Sun C, Huang Y, Wang R
CNS neuroscience & therapeutics 2024 Feb;30(2):e14613
CNS neuroscience & therapeutics 2024 Feb;30(2):e14613
Balancing macrophage polarization via stem cell-derived apoptotic bodies for diabetic wound healing.
Mao J, Qian S, Zhao Q, Zhao B, Lu B, Zhang L, Mao X, Zhang Y, Cui W, Sun X
Med (New York, N.Y.) 2024 Feb 9;5(2):148-168.e8
Med (New York, N.Y.) 2024 Feb 9;5(2):148-168.e8
Complement components regulates ferroptosis in CVB3 viral myocarditis by interatction with TFRC.
Yi L, Yang Y, Hu Y, Wu Z, Kong M, Zuoyuan B, Xin X, Yang Z
Free radical biology & medicine 2024 Feb 20;212:349-359
Free radical biology & medicine 2024 Feb 20;212:349-359
Effectiveness of a Novel PLA2R1 Knock-in Middle Age Rat Model in Repairing Renal Function Damage.
Yang D, Zhang Z, Zhao L, Sui W, Li Y, Zhou Y, Huang B
Cell biochemistry and function 2024 Dec;42(8):e70032
Cell biochemistry and function 2024 Dec;42(8):e70032
Human umbilical cord mesenchymal stem cells mitigate A1 astrocyte neuroinflammation induced by 1,2-dichloroethane via ERBB pathway inhibition.
Du J, Zhong Y, Fan B, Yang X, Ye R, Huang Y, Li Z, Liang B, Xian H, Deng Y, Huang X, Chen X, Shi C, Yu X, Wu B, Yang X, Huang Z
Ecotoxicology and environmental safety 2024 Dec;288:117365
Ecotoxicology and environmental safety 2024 Dec;288:117365
Ponatinib exacerbate renal injury in systemic lupus erythematosus mouse model through PDGFR-PI3K/AKT pathway.
Dong Y, Wang G, Yan X, Ye W, Qiao X, Deng X, Ren P, Jia C, Chen G, Zheng K, Jiang C, Li X
Biochemical pharmacology 2024 Dec;230(Pt 2):116578
Biochemical pharmacology 2024 Dec;230(Pt 2):116578
C3(+) cancer-associated fibroblasts promote tumor growth and therapeutic resistance in gastric cancer via activation of the NF-κB signaling pathway.
Zhao Z, Xiong S, Gao J, Zhang Y, Guo E, Huang Y
Journal of translational medicine 2024 Dec 20;22(1):1130
Journal of translational medicine 2024 Dec 20;22(1):1130
Blockade of OX40/OX40L signaling using anti-OX40L alleviates murine lupus nephritis.
Zhao J, Li L, Feng X, Yin H, Fan X, Gao C, Zhao M, Lu Q
European journal of immunology 2024 Aug;54(8):e2350915
European journal of immunology 2024 Aug;54(8):e2350915
A2 reactive astrocyte-derived exosomes alleviate cerebral ischemia-reperfusion injury by delivering miR-628.
Wang Y, Li H, Sun H, Xu C, Sun H, Wei W, Song J, Jia F, Zhong D, Li G
Journal of cellular and molecular medicine 2024 Aug;28(16):e70004
Journal of cellular and molecular medicine 2024 Aug;28(16):e70004
Quercetin-loaded Human Umbilical cord Mesenchymal Stem Cell-derived sEVs for Spinal Cord Injury Recovery.
Yang C, Xu T, Lu Y, Liu J, Chen C, Wang H, Chen X
Neuroscience 2024 Aug 6;552:14-28
Neuroscience 2024 Aug 6;552:14-28
Study on the underlying molecular mechanism of benzene-induced nervous system damage in mice based on tandem mass tag (TMT) proteomics.
Zheng Z, Li H, Zhang Z, Zhai X, Qin H
Toxicology research 2024 Apr;13(2):tfae036
Toxicology research 2024 Apr;13(2):tfae036
Enriched Environment Inhibits Neurotoxic Reactive Astrocytes via JAK2-STAT3 to Promote Glutamatergic Synaptogenesis and Cognitive Improvement in Chronic Cerebral Hypoperfusion Rats.
Fan B, Lin J, Luo Q, Liao W, Hao C
Neurotoxicity research 2024 Apr 2;42(2):22
Neurotoxicity research 2024 Apr 2;42(2):22
KYNA Ameliorates Glutamate Toxicity of HAND by Enhancing Glutamate Uptake in A2 Astrocytes.
Chen J, Zou J, Huang P, Gao X, Lun J, Li Y, Gong Z, Cao H
International journal of molecular sciences 2024 Apr 12;25(8)
International journal of molecular sciences 2024 Apr 12;25(8)
Complement C1q-mediated microglial synaptic elimination by enhancing desialylation underlies sevoflurane-induced developmental neurotoxicity.
Wang G, Liu HY, Meng XW, Chen Y, Zhao WM, Li WT, Xu HB, Peng K, Ji FH
Cell & bioscience 2024 Apr 1;14(1):42
Cell & bioscience 2024 Apr 1;14(1):42
Effects of liraglutide on astrocyte polarization and neuroinflammation in db/db mice: focus on iron overload and oxidative stress.
An JR, Liu JT, Gao XM, Wang QF, Sun GY, Su JN, Zhang C, Yu JX, Yang YF, Shi Y
Frontiers in cellular neuroscience 2023;17:1136070
Frontiers in cellular neuroscience 2023;17:1136070
TIGIT-Fc fusion protein alleviates murine lupus nephritis through the regulation of SPI-B-PAX5-XBP1 axis-mediated B-cell differentiation.
Zhao J, Li L, Feng X, Gao C, Gao L, Zhan Y, Wang Z, Zhao M, Yin H, Lu Q
Journal of autoimmunity 2023 Sep;139:103087
Journal of autoimmunity 2023 Sep;139:103087
The Oxysterol Receptor EBI2 Links Innate and Adaptive Immunity to Limit IFN Response and Systemic Lupus Erythematosus.
Zhang F, Zhang B, Ding H, Li X, Wang X, Zhang X, Liu Q, Feng Q, Han M, Chen L, Qi L, Yang D, Li X, Zhu X, Zhao Q, Qiu J, Zhu Z, Tang H, Shen N, Wang H, Wei B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(27):e2207108
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(27):e2207108
Knockout of microglial Hv1 proton channel reduces neurotoxic A1 astrocytes and neuronal damage via the ROS/STAT3 pathway after spinal cord injury.
Li Y, Xie Y, Liu R, Wang Z, Chen P, Wang M, Yu Z, Wang W, Luo X
Glia 2023 Oct;71(10):2418-2436
Glia 2023 Oct;71(10):2418-2436
Cell-specific NFIA upregulation promotes epileptogenesis by TRPV4-mediated astrocyte reactivity.
Kong S, Chen TX, Jia XL, Cheng XL, Zeng ML, Liang JY, He XH, Yin J, Han S, Liu WH, Fan YT, Zhou T, Liu YM, Peng BW
Journal of neuroinflammation 2023 Oct 25;20(1):247
Journal of neuroinflammation 2023 Oct 25;20(1):247
Repurposing crizotinib to target RIPK1-dependent cell death.
Yu Y, Li M, Fu S, He X, Hu X, Zhu G, Wang J, You X, Mou Y, Ye Z, Wei J, Zha Y
International immunology 2023 May 8;35(5):221-230
International immunology 2023 May 8;35(5):221-230
Kynurenic acid blunts A1 astrocyte activation against neurodegeneration in HIV-associated neurocognitive disorders.
Lun J, Li Y, Gao X, Gong Z, Chen X, Zou J, Zhou C, Huang Y, Zhou B, Huang P, Cao H
Journal of neuroinflammation 2023 Mar 30;20(1):87
Journal of neuroinflammation 2023 Mar 30;20(1):87
Unrecognized Potent Activities of Colistin Against Clinically Important mcr+ Enterobacteriaceae Revealed in Synergy with Host Immunity.
Kumaraswamy M, Riestra A, Flores A, Uchiyama S, Dahesh S, Bondsäter G, Nilsson V, Chang M, Seo H, Sakoulas G, Nizet V
bioRxiv : the preprint server for biology 2023 Mar 21;
bioRxiv : the preprint server for biology 2023 Mar 21;
Proteomics and transcriptomics profiling reveals distinct aspects of kidney stone related genes in calculi rats.
Zhu W, Qiong D, Yanli G, Min L, Ying Z, Qiyi H, Shenping Z, Xisheng W, Hui L
BMC genomics 2023 Mar 17;24(1):127
BMC genomics 2023 Mar 17;24(1):127
Blocking Two-Pore Domain Potassium Channel TREK-1 Inhibits the Activation of A1-Like Reactive Astrocyte Through the NF-κB Signaling Pathway in a Rat Model of Major Depressive Disorder.
Cong T, Sun Y, Zhou Y, Wu H, Li L, Chu Z, Chen X, Li J, Zhao D, Wang Y, Liu Y, Yin S, Xiao Z
Neurochemical research 2023 Jun;48(6):1737-1754
Neurochemical research 2023 Jun;48(6):1737-1754
Autophagy enables microglia to engage amyloid plaques and prevents microglial senescence.
Choi I, Wang M, Yoo S, Xu P, Seegobin SP, Li X, Han X, Wang Q, Peng J, Zhang B, Yue Z
Nature cell biology 2023 Jul;25(7):963-974
Nature cell biology 2023 Jul;25(7):963-974
Therapeutic hyperthermia regulates complement C3 activation and suppresses tumor development through HSPA5/NFκB/CD55 pathway in nasopharyngeal carcinoma.
Chen C, Ren A, Yi Q, Cai J, Khan M, Lin Y, Huang Z, Lin J, Zhang J, Liu W, Xu A, Tian Y, Yuan Y, Zheng R
Clinical and experimental immunology 2023 Jul 21;213(2):221-234
Clinical and experimental immunology 2023 Jul 21;213(2):221-234
Tandem Mass Tag-based proteomics analysis reveals the vital role of inflammation in traumatic brain injury in a mouse model.
Dong JQ, Ge QQ, Lu SH, Yang MS, Zhuang Y, Zhang B, Niu F, Xu XJ, Liu BY
Neural regeneration research 2023 Jan;18(1):155-161
Neural regeneration research 2023 Jan;18(1):155-161
PPARγ Acetylation Orchestrates Adipose Plasticity and Metabolic Rhythms.
He Y, B'nai Taub A, Yu L, Yao Y, Zhang R, Zahr T, Aaron N, LeSauter J, Fan L, Liu L, Tazebay R, Que J, Pajvani U, Wang L, Silver R, Qiang L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jan;10(2):e2204190
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jan;10(2):e2204190
HIF-1α participates in secondary brain injury through regulating neuroinflammation.
Xu X, Yang M, Zhang B, Dong J, Zhuang Y, Ge Q, Niu F, Liu B
Translational neuroscience 2023 Jan 1;14(1):20220272
Translational neuroscience 2023 Jan 1;14(1):20220272
Qihuang Granule protects the retinal pigment epithelium from oxidative stress via regulation of the alternative complement pathway.
Wang Y, Shen H, Pang L, Qiu B, Yuan Y, Guan X, Xiang X
BMC complementary medicine and therapies 2023 Feb 18;23(1):55
BMC complementary medicine and therapies 2023 Feb 18;23(1):55
Neuron-Derived Exosomes Promote the Recovery of Spinal Cord Injury by Modulating Nerve Cells in the Cellular Microenvironment of the Lesion Area.
Xu Y, Zhu ZH, Xu X, Sun HT, Zheng HM, Zhang JL, Wang HH, Fang JW, Liu YZ, Huang LL, Song ZW, Liu JB
Molecular neurobiology 2023 Aug;60(8):4502-4516
Molecular neurobiology 2023 Aug;60(8):4502-4516
Inhibition of acid sphingomyelinase reduces reactive astrocyte secretion of mitotoxic extracellular vesicles and improves Alzheimer's disease pathology in the 5xFAD mouse.
Crivelli SM, Quadri Z, Vekaria HJ, Zhu Z, Tripathi P, Elsherbini A, Zhang L, Sullivan PG, Bieberich E
Acta neuropathologica communications 2023 Aug 21;11(1):135
Acta neuropathologica communications 2023 Aug 21;11(1):135
Hemocompatibility tuning of an innovative glutaraldehyde-free preparation strategy using riboflavin/UV crosslinking and electron irradiation of bovine pericardium for cardiac substitutes.
Dittfeld C, Welzel C, König U, Jannasch A, Alexiou K, Blum E, Bronder S, Sperling C, Maitz MF, Tugtekin SM
Biomaterials advances 2023 Apr;147:213328
Biomaterials advances 2023 Apr;147:213328
Integrated transcriptomics and metabolomics analysis reveals that C3 and C5 are vital targets of DuZhi Wan in protecting against cerebral ischemic injury.
Hou JY, Cao GZ, Tian LL, Zhou R, Zhang Y, Xu H, Wu HW, Wang LF, Yang HJ, Zhang JJ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113703
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113703
SIRT3 alleviates mitochondrial dysfunction induced by recurrent low glucose and improves the supportive function of astrocytes to neurons.
Gao R, Chen Z, Wu Y, Chen R, Zheng W, Qi L, Liu X, Liu X, Liu L
Free radical biology & medicine 2022 Nov 20;193(Pt 1):405-420
Free radical biology & medicine 2022 Nov 20;193(Pt 1):405-420
Neutral Sphingomyelinase 2 Mediates Oxidative Stress Effects on Astrocyte Senescence and Synaptic Plasticity Transcripts.
Zhu Z, Quadri Z, Crivelli SM, Elsherbini A, Zhang L, Tripathi P, Qin H, Roush E, Spassieva SD, Nikolova-Karakashian M, McClintock TS, Bieberich E
Molecular neurobiology 2022 May;59(5):3233-3253
Molecular neurobiology 2022 May;59(5):3233-3253
Cyanidin-3-O-glucoside ameliorates cadmium induced uterine epithelium proliferation in mice.
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Journal of hazardous materials 2022 Mar 5;425:127571
Journal of hazardous materials 2022 Mar 5;425:127571
Natural antibodies and CRP drive anaphylatoxin production by urate crystals.
Wessig AK, Hoffmeister L, Klingberg A, Alberts A, Pich A, Brand K, Witte T, Neumann K
Scientific reports 2022 Mar 16;12(1):4483
Scientific reports 2022 Mar 16;12(1):4483
1,25-dihydroxyvitamin D3 ameliorates lupus nephritis through inhibiting the NF-κB and MAPK signalling pathways in MRL/lpr mice.
Li X, Liu J, Zhao Y, Xu N, Lv E, Ci C, Li X
BMC nephrology 2022 Jul 8;23(1):243
BMC nephrology 2022 Jul 8;23(1):243
Total coumarin derivates from Hydrangea paniculata attenuate renal injuries in cationized-BSA induced membranous nephropathy by inhibiting complement activation and interleukin 10-mediated interstitial fibrosis.
Wang W, Sheng L, Chen Y, Li Z, Wu H, Ma J, Zhang D, Chen X, Zhang S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Feb;96:153886
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Feb;96:153886
Pandemic Influenza Infection Promotes Streptococcus pneumoniae Infiltration, Necrotic Damage, and Proteomic Remodeling in the Heart.
Platt MP, Lin YH, Wiscovitch-Russo R, Yu Y, Gonzalez-Juarbe N
mBio 2022 Feb 22;13(1):e0325721
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Cornuside Is a Potential Agent against Alzheimer's Disease via Orchestration of Reactive Astrocytes.
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Nutrients 2022 Aug 3;14(15)
Nutrients 2022 Aug 3;14(15)
Activation of C3 and C5 May Be Involved in the Inflammatory Progression of PCM and GM.
Li XQ, Sun HG, Wang XH, Zhang HJ, Zhang XS, Yu Y, Liu J, Guo QQ, Yang ZL
Inflammation 2022 Apr;45(2):739-752
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Duong PC, McCabe TC, Riley GF, Holmes HL, Piermarini PM, Romero MF, Gillen CM
Insect biochemistry and molecular biology 2022 Apr;143:103729
Insect biochemistry and molecular biology 2022 Apr;143:103729
Exogenous Biological Renal Support Improves Kidney Function in Mice With Rhabdomyolysis-Induced Acute Kidney Injury.
Liu C, Chi K, Geng X, Hong Q, Mao Z, Huang Q, Liu D, Wang Y, Zhang Y, Zhou F, Cai G, Chen X, Sun X
Frontiers in medicine 2021;8:655787
Frontiers in medicine 2021;8:655787
Proteomic Landscape of Exosomes Reveals the Functional Contributions of CD151 in Triple-Negative Breast Cancer.
Li S, Li X, Yang S, Pi H, Li Z, Yao P, Zhang Q, Wang Q, Shen P, Li X, Ji J
Molecular & cellular proteomics : MCP 2021;20:100121
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Extracellular vesicles derived from CD73 modified human umbilical cord mesenchymal stem cells ameliorate inflammation after spinal cord injury.
Zhai X, Chen K, Yang H, Li B, Zhou T, Wang H, Zhou H, Chen S, Zhou X, Wei X, Bai Y, Li M
Journal of nanobiotechnology 2021 Sep 8;19(1):274
Journal of nanobiotechnology 2021 Sep 8;19(1):274
Kinetic Multi-omic Analysis of Responses to SARS-CoV-2 Infection in a Model of Severe COVID-19.
Cantwell AM, Singh H, Platt M, Yu Y, Lin YH, Ikeno Y, Hubbard G, Xiang Y, Gonzalez-Juarbe N, Dube PH
Journal of virology 2021 Sep 27;95(20):e0101021
Journal of virology 2021 Sep 27;95(20):e0101021
Complement C3 Aggravates Post-epileptic Neuronal Injury Via Activation of TRPV1.
Jiang GT, Shao L, Kong S, Zeng ML, Cheng JJ, Chen TX, Han S, Yin J, Liu WH, He XH, Liu YM, Gongga L, Peng BW
Neuroscience bulletin 2021 Oct;37(10):1427-1440
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FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21330
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21330
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Journal of dairy science 2021 Aug;104(8):8411-8424
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Nature communications 2020 Feb 7;11(1):778
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Scientific reports 2020 Apr 14;10(1):6391
Scientific reports 2020 Apr 14;10(1):6391
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Cardiology in the young 2017 Nov;27(9):1786-1796
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Scientific reports 2017 Jul 10;7(1):5009
Scientific reports 2017 Jul 10;7(1):5009
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Journal of molecular endocrinology 2017 Aug;59(2):105-119
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International journal of molecular sciences 2016 Dec 7;17(12)
International journal of molecular sciences 2016 Dec 7;17(12)
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The C3 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human C3. This antibody recognizes human antigen. The C3 antibody has been validated for the following applications: ELISA, WB analysis.
