AF2307

antibody from Novus Biologicals

Targeting: MBL2 COLEC1, MBL

Western blot (Data presented on provider website)

Antibody Data

Product number

AF2307

Provider

Novus Biologicals

Product name

Goat Polyclonal MBL Antibody

Antibody type

Polyclonal

Description

Immunogen affinity purified. Detects human MBL in ELISAs and Western blots. In sandwich ELISAs, less than 0.05% cross-reactivity with recombinant mouse (rm) MBL and rmMBL-2 is observed.

Reactivity

Human

Host

Goat

Isotype

IgG

Vial size

100 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.

References

Submitted references

Mannan-Binding Lectin Suppresses Peptidoglycan-Induced TLR2 Activation and Inflammatory Responses.

Wang F, Li Y, Yang C, Mu Y, Wang Y, Zhang W, Yang Y, Chen C, Song S, Shen Z, Wang W, Li J, Zhai J, Guo K, Sun R, Yu L, Wang M
Mediators of inflammation 2019;2019:1349784

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Moraxella catarrhalis Evades Host Innate Immunity via Targeting Cartilage Oligomeric Matrix Protein.

Liu G, Gradstedt H, Ermert D, Englund E, Singh B, Su YC, Johansson ME, Aspberg A, Agarwal V, Riesbeck K, Blom AM
Journal of immunology (Baltimore, Md. : 1950) 2016 Feb 1;196(3):1249-58

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Mannan-binding lectin inhibits Candida albicans-induced cellular responses in PMA-activated THP-1 cells through Toll-like receptor 2 and Toll-like receptor 4.

Wang M, Wang F, Yang J, Zhao D, Wang H, Shao F, Wang W, Sun R, Ling M, Zhai J, Song S
PloS one 2013;8(12):e83517

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A metalloproteinase karilysin present in the majority of Tannerella forsythia isolates inhibits all pathways of the complement system.

Jusko M, Potempa J, Karim AY, Ksiazek M, Riesbeck K, Garred P, Eick S, Blom AM
Journal of immunology (Baltimore, Md. : 1950) 2012 Mar 1;188(5):2338-49

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Scabies mite peritrophins are potential targets of human host innate immunity.

Mika A, Goh P, Holt DC, Kemp DJ, Fischer K
PLoS neglected tropical diseases 2011 Sep;5(9):e1331

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Serglycin inhibits the classical and lectin pathways of complement via its glycosaminoglycan chains: implications for multiple myeloma.

Skliris A, Happonen KE, Terpos E, Labropoulou V, Børset M, Heinegård D, Blom AM, Theocharis AD
European journal of immunology 2011 Feb;41(2):437-49