346804

antibody from BioLegend

Targeting: MBL2 COLEC1, MBL

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

346804

Provider

BioLegend

Product name

Alexa Fluor® 647 anti-human Pro-Major Basic Protein 1 (ProMBP1) [J175-7D4]

Antibody type

Monoclonal

Antigen

Recombinant pro-form of human major basic protein 1

Description

Pro-form of Major Basic Protein 1 (ProMBP1) is composed of a strongly acidic 90-residue propart and a highly basic mature portion of 117 residues. It is an extensively and very heterogeneously glycosylated proteoglycan. ProMBP1 is processed to 14 kD MBP1 by convertase during maturation and localized in cell granule core. The mature MBP1 is a cytotoxic protein. The mAb J175-7D4 binds ProMBP1 and intermediate ProMBP1, but not mature MBP1. It  specifically stain basophils, does not stain eosinophils, granulocytes, and mast cells and can be used as a marker for human basophils.

Reactivity

Human

Host

Mouse

Conjugate

Red dye

Isotype

IgG

Vial size

100 tests

Storage

The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.