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- References [11]
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- Product number
- 18221-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- IRAK4 antibody
- Antibody type
- Polyclonal
- Description
- IRAK4 antibody (Cat. #18221-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Design, Synthesis, and Evaluation of Nucleolin-Bridged, MDM2-Recruiting IRAK4 Degraders for the Treatment of Autoimmune Diseases.
BAP1 Represses Sequential Activation of IRAKs and NF-κB Signaling in Pancreatic Cancer.
Global MicroRNA Profiling of HSV-1 Infected Cornea Identifies miR-329 as a Novel Regulator of Virus Infection.
MicroRNA-27a-5p Downregulates Expression of Proinflammatory Cytokines in Lipopolysaccharide-Stimulated Human Dental Pulp Cells via the NF-κB Signaling Pathway.
IL-1α facilitates GSH synthesis to counteract oxidative stress in oral squamous cell carcinoma under glucose-deprivation.
Let-7b-TLR7 Signaling Axis Contributes to the Anesthesia/Surgery-Induced Cognitive Impairment.
Integrated characterization of hepatobiliary tumor organoids provides a potential landscape of pharmacogenomic interactions.
Herbal compound cepharanthine attenuates inflammatory arthritis by blocking macrophage M1 polarization.
Euphorbia Factor L2 ameliorates the Progression of K/BxN Serum-Induced Arthritis by Blocking TLR7 Mediated IRAK4/IKKβ/IRF5 and NF-kB Signaling Pathways.
Capsular Polysaccharide is a Main Component of Mycoplasma ovipneumoniae in the Pathogen-Induced Toll-Like Receptor-Mediated Inflammatory Responses in Sheep Airway Epithelial Cells.
Extracts of Salvia-Nelumbinis Naturalis Ameliorate Nonalcoholic Steatohepatitis via Inhibiting Gut-Derived Endotoxin Mediated TLR4/NF-κB Activation.
Feng Z, Zhang X, Ding Y, Zhang K, Qiu F, Xie D, Lu A, Zhang L, Liang C
Journal of medicinal chemistry 2026 Feb 26;69(4):4855-4872
Journal of medicinal chemistry 2026 Feb 26;69(4):4855-4872
BAP1 Represses Sequential Activation of IRAKs and NF-κB Signaling in Pancreatic Cancer.
Zhao Y, Liang X, Wei R, Guo F, Qin G, Yu H, Liu J, Xia W, Gou S, Wu H, Zhou Y
International journal of biological sciences 2025;21(5):1949-1965
International journal of biological sciences 2025;21(5):1949-1965
Global MicroRNA Profiling of HSV-1 Infected Cornea Identifies miR-329 as a Novel Regulator of Virus Infection.
Sharma P, Naqvi RA, Borase H, Kapoor D, Valverde A, Capistrano K, Yadavalli T, Naqvi AR, Shukla D
Investigative ophthalmology & visual science 2025 Feb 3;66(2):61
Investigative ophthalmology & visual science 2025 Feb 3;66(2):61
MicroRNA-27a-5p Downregulates Expression of Proinflammatory Cytokines in Lipopolysaccharide-Stimulated Human Dental Pulp Cells via the NF-κB Signaling Pathway.
Wang S, Kawashima N, Han P, Sunada-Nara K, Yu Z, Tazawa K, Fujii M, Kieu TQ, Okiji T
International journal of molecular sciences 2024 Sep 7;25(17)
International journal of molecular sciences 2024 Sep 7;25(17)
IL-1α facilitates GSH synthesis to counteract oxidative stress in oral squamous cell carcinoma under glucose-deprivation.
Ji Y, Zhang Z, Zhao X, Li Z, Hu X, Zhang M, Pan X, Wang X, Chen W
Cancer letters 2024 May 1;589:216833
Cancer letters 2024 May 1;589:216833
Let-7b-TLR7 Signaling Axis Contributes to the Anesthesia/Surgery-Induced Cognitive Impairment.
Deng L, Gao R, Chen H, Jiao B, Zhang C, Wei L, Yan C, Ye-Lehmann S, Zhu T, Chen C
Molecular neurobiology 2024 Mar;61(3):1818-1832
Molecular neurobiology 2024 Mar;61(3):1818-1832
Integrated characterization of hepatobiliary tumor organoids provides a potential landscape of pharmacogenomic interactions.
Zhu Y, Tang S, Yuan Q, Fu J, He J, Liu Z, Zhao X, Li Y, Zhao Y, Zhang Y, Zhang X, Zhang Y, Zhu Y, Wang W, Zheng B, Wu R, Wu T, Yang S, Qiu X, Shen S, Hu J, Chen L, Wang Y, Wang H, Gao D, Chen L
Cell reports. Medicine 2024 Feb 20;5(2):101375
Cell reports. Medicine 2024 Feb 20;5(2):101375
Herbal compound cepharanthine attenuates inflammatory arthritis by blocking macrophage M1 polarization.
Lu C, Cheng RJ, Zhang Q, Hu Y, Pu Y, Wen J, Zhong Y, Tang Z, Wu L, Wei S, Tsou PS, Fox DA, Li S, Luo Y, Liu Y
International immunopharmacology 2023 Dec;125(Pt B):111175
International immunopharmacology 2023 Dec;125(Pt B):111175
Euphorbia Factor L2 ameliorates the Progression of K/BxN Serum-Induced Arthritis by Blocking TLR7 Mediated IRAK4/IKKβ/IRF5 and NF-kB Signaling Pathways.
Tang J, Cheng X, Yi S, Zhang Y, Tang Z, Zhong Y, Zhang Q, Pan B, Luo Y
Frontiers in pharmacology 2021;12:773592
Frontiers in pharmacology 2021;12:773592
Capsular Polysaccharide is a Main Component of Mycoplasma ovipneumoniae in the Pathogen-Induced Toll-Like Receptor-Mediated Inflammatory Responses in Sheep Airway Epithelial Cells.
Jiang Z, Song F, Li Y, Xue D, Deng G, Li M, Liu X, Wang Y
Mediators of inflammation 2017;2017:9891673
Mediators of inflammation 2017;2017:9891673
Extracts of Salvia-Nelumbinis Naturalis Ameliorate Nonalcoholic Steatohepatitis via Inhibiting Gut-Derived Endotoxin Mediated TLR4/NF-κB Activation.
Shu X, Wang M, Xu H, Liu Y, Huang J, Yao Z, Zhang L
Evidence-based complementary and alternative medicine : eCAM 2017;2017:9208314
Evidence-based complementary and alternative medicine : eCAM 2017;2017:9208314
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 18221-1-AP( IRAK4 Antibody) at dilution of 1:300
- Other comments
- WB
