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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [12]
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- Product number
- NB500-597 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Rabbit Polyclonal IRAK4 Antibody
- Antibody type
- Polyclonal
- Antigen
- This antibody was developed against a mixture of synthetic peptides containing amino acids 38-54 and 120-136 of mouse IRAK-4.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Vial size
- 0.2ml
- Concentration
- 0.5 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Submitted references The inhibition of RANKL expression in fibroblasts attenuate CoCr particles induced aseptic prosthesis loosening via the MyD88-independent TLR signaling pathway.
Inhibition of lethal inflammatory responses through the targeting of membrane-associated Toll-like receptor 4 signaling complexes with a Smad6-derived peptide.
Expression and activation of intracellular receptors TLR7, TLR8 and TLR9 in peripheral blood monocytes from HIV-infected patients.
Caveolin-1 deficiency dampens Toll-like receptor 4 signaling through eNOS activation.
Blockade of inducible costimulator pathway to prevent acute rejection in rat liver transplantation.
Glycine attenuates endotoxin-induced liver injury by downregulating TLR4 signaling in Kupffer cells.
Cross-talk between IRAK-4 and the NADPH oxidase.
Direct extracellular interaction between the early secreted antigen ESAT-6 of Mycobacterium tuberculosis and TLR2 inhibits TLR signaling in macrophages.
Smad6 negatively regulates interleukin 1-receptor-Toll-like receptor signaling through direct interaction with the adaptor Pellino-1.
Glycine blunts transplantative liver ischemia-reperfusion injury by downregulating interleukin 1 receptor associated kinase-4.
Prolonged Toll-like receptor stimulation leads to down-regulation of IRAK-4 protein.
Involvement of reactive oxygen species in Toll-like receptor 4-dependent activation of NF-kappa B.
Li, Wang H, Li Z, Wang C, Xiao F, Gao Y, Zhang X, Wang P, Peng J, Cai G, Zuo B, Shen Y, Qi J, Qian N, Deng L, Song W, Zhang X, Shen L, Chen X
Biochemical and biophysical research communications 2018 Sep 5;503(2):1115-1122
Biochemical and biophysical research communications 2018 Sep 5;503(2):1115-1122
Inhibition of lethal inflammatory responses through the targeting of membrane-associated Toll-like receptor 4 signaling complexes with a Smad6-derived peptide.
Lee YS, Park JS, Jung SM, Kim SD, Kim JH, Lee JY, Jung KC, Mamura M, Lee S, Kim SJ, Bae YS, Park SH
EMBO molecular medicine 2015 May;7(5):577-92
EMBO molecular medicine 2015 May;7(5):577-92
Expression and activation of intracellular receptors TLR7, TLR8 and TLR9 in peripheral blood monocytes from HIV-infected patients.
Valencia Pacheco GJ, Pinzón Herrera F, Cruz López JJ, Vera Gamboa Ldel C, Pavía Ruiz N, Santos Rivero A, Sánchez Lugo S, Puerto F
Colombia medica (Cali, Colombia) 2013 Apr;44(2):92-9
Colombia medica (Cali, Colombia) 2013 Apr;44(2):92-9
Caveolin-1 deficiency dampens Toll-like receptor 4 signaling through eNOS activation.
Mirza MK, Yuan J, Gao XP, Garrean S, Brovkovych V, Malik AB, Tiruppathi C, Zhao YY
The American journal of pathology 2010 May;176(5):2344-51
The American journal of pathology 2010 May;176(5):2344-51
Blockade of inducible costimulator pathway to prevent acute rejection in rat liver transplantation.
Chen Y, Liu H, Liu Z, Liang S, Chen J, Long F, Peng Y, Yan L, Gong J
American journal of surgery 2009 Aug;198(2):244-9
American journal of surgery 2009 Aug;198(2):244-9
Glycine attenuates endotoxin-induced liver injury by downregulating TLR4 signaling in Kupffer cells.
Xu FL, You HB, Li XH, Chen XF, Liu ZJ, Gong JP
American journal of surgery 2008 Jul;196(1):139-48
American journal of surgery 2008 Jul;196(1):139-48
Cross-talk between IRAK-4 and the NADPH oxidase.
Pacquelet S, Johnson JL, Ellis BA, Brzezinska AA, Lane WS, Munafo DB, Catz SD
The Biochemical journal 2007 May 1;403(3):451-61
The Biochemical journal 2007 May 1;403(3):451-61
Direct extracellular interaction between the early secreted antigen ESAT-6 of Mycobacterium tuberculosis and TLR2 inhibits TLR signaling in macrophages.
Pathak SK, Basu S, Basu KK, Banerjee A, Pathak S, Bhattacharyya A, Kaisho T, Kundu M, Basu J
Nature immunology 2007 Jun;8(6):610-8
Nature immunology 2007 Jun;8(6):610-8
Smad6 negatively regulates interleukin 1-receptor-Toll-like receptor signaling through direct interaction with the adaptor Pellino-1.
Choi KC, Lee YS, Lim S, Choi HK, Lee CH, Lee EK, Hong S, Kim IH, Kim SJ, Park SH
Nature immunology 2006 Oct;7(10):1057-65
Nature immunology 2006 Oct;7(10):1057-65
Glycine blunts transplantative liver ischemia-reperfusion injury by downregulating interleukin 1 receptor associated kinase-4.
Liu ZJ, Yan LN, Li SW, You HB, Gong JP
Acta pharmacologica Sinica 2006 Nov;27(11):1479-86
Acta pharmacologica Sinica 2006 Nov;27(11):1479-86
Prolonged Toll-like receptor stimulation leads to down-regulation of IRAK-4 protein.
Hatao F, Muroi M, Hiki N, Ogawa T, Mimura Y, Kaminishi M, Tanamoto K
Journal of leukocyte biology 2004 Oct;76(4):904-8
Journal of leukocyte biology 2004 Oct;76(4):904-8
Involvement of reactive oxygen species in Toll-like receptor 4-dependent activation of NF-kappa B.
Asehnoune K, Strassheim D, Mitra S, Kim JY, Abraham E
Journal of immunology (Baltimore, Md. : 1950) 2004 Feb 15;172(4):2522-9
Journal of immunology (Baltimore, Md. : 1950) 2004 Feb 15;172(4):2522-9
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