Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations [0]
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- Product number
- ABIN358126 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (pSer191) antibody
- Antibody type
- Polyclonal
- Description
- Protein G Affinity Chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- pSer191
- Vial size
- 0.4 mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references The solution structure of FADD death domain. Structural basis of death domain interactions of Fas and FADD.
A mouse Fas-associated protein with homology to the human Mort1/FADD protein is essential for Fas-induced apoptosis.
TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways.
Jeong EJ, Bang S, Lee TH, Park YI, Sim WS, Kim KS
The Journal of biological chemistry 1999 Jun 4;274(23):16337-42
The Journal of biological chemistry 1999 Jun 4;274(23):16337-42
A mouse Fas-associated protein with homology to the human Mort1/FADD protein is essential for Fas-induced apoptosis.
Zhang J, Winoto A
Molecular and cellular biology 1996 Jun;16(6):2756-63
Molecular and cellular biology 1996 Jun;16(6):2756-63
TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways.
Hsu H, Shu HB, Pan MG, Goeddel DV
Cell 1996 Jan 26;84(2):299-308
Cell 1996 Jan 26;84(2):299-308
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