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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Product number
- ABIN371639 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) antibody (Sepharose)
- Antibody type
- Monoclonal
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Agarose/Sepharose
- Isotype
- IgG
- Antibody clone number
- 1A11
- Vial size
- 50 tests
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Store protected from light. Avoid repeated freezing and thawing.Shelf life: one year from despatch.
Submitted references Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3.
A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes.
FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex.
Contenders in FasL/TNF death signaling.
A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain.
Wieder T, Essmann F, Prokop A, Schmelz K, Schulze-Osthoff K, Beyaert R, Dörken B, Daniel PT
Blood 2001 Mar 1;97(5):1378-87
Blood 2001 Mar 1;97(5):1378-87
A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes.
Newton K, Harris AW, Bath ML, Smith KG, Strasser A
The EMBO journal 1998 Feb 2;17(3):706-18
The EMBO journal 1998 Feb 2;17(3):706-18
FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex.
Muzio M, Chinnaiyan AM, Kischkel FC, O'Rourke K, Shevchenko A, Ni J, Scaffidi C, Bretz JD, Zhang M, Gentz R, Mann M, Krammer PH, Peter ME, Dixit VM
Cell 1996 Jun 14;85(6):817-27
Cell 1996 Jun 14;85(6):817-27
Contenders in FasL/TNF death signaling.
Cleveland JL, Ihle JN
Cell 1995 May 19;81(4):479-82
Cell 1995 May 19;81(4):479-82
A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain.
Boldin MP, Varfolomeev EE, Pancer Z, Mett IL, Camonis JH, Wallach D
The Journal of biological chemistry 1995 Apr 7;270(14):7795-8
The Journal of biological chemistry 1995 Apr 7;270(14):7795-8
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