ADI-AAP-210-D

antibody from Enzo Life Sciences

Targeting: FADD GIG3, MORT1

Western blot (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

ADI-AAP-210-D

Provider

Enzo Life Sciences

Proper citation

Enzo Life Sciences Cat#ADI-AAP-210-D, RRID:AB_2039115

Product name

FADD polyclonal antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide

Description

Peptide affinity purified.

Reactivity

Human, Rat, Simian

Host

Rabbit

Vial size

50 μg

Storage

-20°C

Handling

Avoid freeze/thaw cycles.

References

Submitted references

Hepatocyte Fas-associating death domain protein/mediator of receptor-induced toxicity (FADD/MORT1) levels increase in response to pro-apoptotic stimuli.

Kim PK, Wang Y, Gambotto A, Kim YM, Weller R, Zuckerbraun BS, Hua Y, Watkins SC, Billiar TR
The Journal of biological chemistry 2002 Oct 11;277(41):38855-62

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B cell receptor cross-linking triggers a caspase-8-dependent apoptotic pathway that is independent of the death effector domain of Fas-associated death domain protein.

Besnault L, Schrantz N, Auffredou MT, Leca G, Bourgeade MF, Vazquez A
Journal of immunology (Baltimore, Md. : 1950) 2001 Jul 15;167(2):733-40

Immunocytochemistry

Supportive validation

Submitted by

Enzo Life Sciences (provider)

Main image

Experimental details

Western blot analysis: Lane 1: MW marker, Lane 2: HeLa.

Supportive validation

Submitted by

Enzo Life Sciences (provider)

Main image

Experimental details

IHC Analysis: Human kidney tissue stained with FADD, pAb at 10µg/ml.

Supportive validation

Submitted by

Enzo Life Sciences (provider)

Main image

Experimental details

IHC Analysis: Human placenta tissue stained with FADD, pAb at 10µg/ml.