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- Antigen structure
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- Product number
- NBP1-46851 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-46851, RRID:AB_10658241
- Product name
- Rabbit Polyclonal Blooms Syndrome Protein Blm Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.05 ml
- Concentration
- 4.8 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Bloom's syndrome helicase and Mus81 are required to induce transient double-strand DNA breaks in response to DNA replication stress.
Phosphorylation of BLM, dissociation from topoisomerase IIIalpha, and colocalization with gamma-H2AX after topoisomerase I-induced replication damage.
Shimura T, Torres MJ, Martin MM, Rao VA, Pommier Y, Katsura M, Miyagawa K, Aladjem MI
Journal of molecular biology 2008 Jan 25;375(4):1152-64
Journal of molecular biology 2008 Jan 25;375(4):1152-64
Phosphorylation of BLM, dissociation from topoisomerase IIIalpha, and colocalization with gamma-H2AX after topoisomerase I-induced replication damage.
Rao VA, Fan AM, Meng L, Doe CF, North PS, Hickson ID, Pommier Y
Molecular and cellular biology 2005 Oct;25(20):8925-37
Molecular and cellular biology 2005 Oct;25(20):8925-37
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Supportive validation
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- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Blooms Syndrome Protein Blm [p Thr99] Antibody [NBP1-46851] - Western blot analysis of Blooms Syndrome Protein Blm phosphorylated at Thr99 in MDA-MB-231 cells A) not treated and B) treated with 1uM camptothecin using NBP1-46851. Image courtesy of Dr. Keli Agama.
