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- Western blot [5]
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- Immunoprecipitation [1]
- Immunohistochemistry [1]
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- Product number
- GTX118741 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX118741, RRID:AB_10624939
- Product name
- Mre11 antibody
- Antibody type
- Polyclonal
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
Submitted references Degradation of a Novel DNA Damage Response Protein, Tankyrase 1 Binding Protein 1, following Adenovirus Infection.
Inhibition of non-homologous end joining in Fanconi Anemia cells results in rescue of survival after interstrand crosslinks but sensitization to replication associated double-strand breaks.
The E1B19K-deleted oncolytic adenovirus mutant AdΔ19K sensitizes pancreatic cancer cells to drug-induced DNA-damage by down-regulating Claspin and Mre11.
Timely synthesis of the adenovirus type 5 E1B 55-kilodalton protein is required for efficient genome replication in normal human cells.
Chalabi Hagkarim N, Ryan EL, Byrd PJ, Hollingworth R, Shimwell NJ, Agathanggelou A, Vavasseur M, Kolbe V, Speiseder T, Dobner T, Stewart GS, Grand RJ
Journal of virology 2018 Jun 15;92(12)
Journal of virology 2018 Jun 15;92(12)
Inhibition of non-homologous end joining in Fanconi Anemia cells results in rescue of survival after interstrand crosslinks but sensitization to replication associated double-strand breaks.
Eccles LJ, Bell AC, Powell SN
DNA repair 2018 Apr;64:1-9
DNA repair 2018 Apr;64:1-9
The E1B19K-deleted oncolytic adenovirus mutant AdΔ19K sensitizes pancreatic cancer cells to drug-induced DNA-damage by down-regulating Claspin and Mre11.
Pantelidou C, Cherubini G, Lemoine NR, Halldén G
Oncotarget 2016 Mar 29;7(13):15703-24
Oncotarget 2016 Mar 29;7(13):15703-24
Timely synthesis of the adenovirus type 5 E1B 55-kilodalton protein is required for efficient genome replication in normal human cells.
Chahal JS, Flint SJ
Journal of virology 2012 Mar;86(6):3064-72
Journal of virology 2012 Mar;86(6):3064-72
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Enhanced validation
Supportive validation
- Submitted by
- GeneTex (provider)
- Enhanced method
- Genetic validation
- Main image
- Experimental details
- Non-transfected (¡V) and transfected (+) HeLa whole cell extracts (30 ?g) were separated by 7.5% SDS-PAGE, and the membrane was blotted with Mre11 antibody (GTX118741) diluted at 1:2000.
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Sample (30 ug of whole cell lysate) A: A431 (GTX27909) 7.5% SDS PAGE GTX118741 diluted at 1:1000
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Mre11 antibody detects MRE11A protein by Western blot analysis.A. 30 ?g C8D30 whole cell lysate/extract B. 30 ?g NIH-3T3 whole cell lysate/extract7.5 % SDS-PAGEMre11 antibody (GTX118741) dilution: 1:1000
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Mre11 antibody detects MRE11A protein by Western blot analysis.A. 30 ?g PC-12 whole cell lysate/extract 7.5 % SDS-PAGEMre11 antibody (GTX118741) dilution: 1:1000
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Non-transfected (¡V) and transfected (+) HeLa whole cell extracts (30 ?g) were separated by 7.5% SDS-PAGE, and the membrane was blotted with Mre11 antibody (GTX118741) diluted at 1:2000.
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Immunofluorescence analysis of paraformaldehyde-fixed A431, using Mre11(GTX118741) antibody at 1:200 dilution.
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Immunoprecipitation of Mre11 protein from HeLa whole cell extracts using 5 £gg of Mre11 antibody (GTX118741).Western blot analysis was performed using Mre11 antibody (GTX118741).EasyBlot anti-Rabbit IgG (GTX221666-01) was used as a secondary reagent.
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded BT474 xenograft, using Mre11(GTX118741) antibody at 1:500 dilution.
