311301

antibody from BioLegend
Targeting: CD55 CR, CROM, DAF, TC
Provider product page for 311301

Antibody data

Product number
311301 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#311301, RRID:AB_314858
Product name
Purified anti-human CD55
Antibody type
Monoclonal
Antigen
CD55
Description
CD55 is a 60-70 kD glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein also known as decay-accelerating factor (DAF). It is expressed on hematopoietic cells including erythrocytes and many non-hematopoietic cells. CD55 accelerates the dissociation of the components of the C3-convertases (namely C2a from C4b in the C4bC2a complex, a C3-convertase of the classical pathway, and factor Bb from the C3bBb complex, a C3-convertase of the alternative pathway) to protect cells from inappropriate damage caused by autologous complement. CD55 has been reported to reduce the efficiency of NK cell lysis and induce signal transduction in T cells. CD55 has also been shown to interact with CD97 and bind to Coxsackie and Echovirus.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Isotype
IgG
Vial size
25 µg
Concentration
0.5 mg/ml
Storage
The antibody solution should be stored undiluted at 4°C.
CD55 protein structure - 311301 shown in red.