abx010780

antibody from Abbexa

Targeting: FGR c-fgr, p55c-fgr, SRC2

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

abx010780

Provider

Abbexa

Product name

Tyrosine-Protein Kinase Fgr (FGR) Antibody

Antibody type

Monoclonal

Description

FGR: Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog, also known as SRC2; c-fgr; c-src2; FLJ43153; MGC75096; p55c-fgr; p58c-fgr. It is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta 2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Reactivity

Human, Mouse

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.