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Learn14903-1-AP
antibody from Proteintech Group
Targeting: SNAP25
bA416N4.2, dJ1068F16.2, RIC-4, RIC4, SEC9, SNAP, SNAP-25
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [21]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 14903-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14903-1-AP, RRID:AB_2192051
- Product name
- SNAP25 antibody
- Antibody type
- Polyclonal
- Description
- SNAP25 antibody (Cat. #14903-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Clinical and functional characterization of a novel KCNJ11 (c.101G > A, p.R34H) mutation associated with maturity-onset diabetes mellitus of the young type 13.
Phosphorylation of Doc2 by EphB2 modulates Munc13-mediated SNARE complex assembly and neurotransmitter release.
Bavachin ameliorates neuroinflammation and depressive-like behaviors in streptozotocin-induced diabetic mice through the inhibition of PKCδ.
L116 Deletion in CSPα Promotes α-Synuclein Aggregation and Neurodegeneration.
Psoralen protects neurons and alleviates neuroinflammation by regulating microglial M1/M2 polarization via inhibition of the Fyn-PKCδ pathway.
Intrathecal Injection of Botulinum Toxin Type A has an Analgesic Effect in Male Rats CCI Model by Inhibiting the Activation of Spinal P2X4R.
Reduced synaptic proteins and SNARE complexes in Down syndrome with Alzheimer's disease and the Dp16 mouse Down syndrome model: Impact of APP gene dose.
Comparative study of PRPH2 D2 loop mutants reveals divergent disease mechanism in rods and cones.
Rabphilin 3A binds the N-peptide of SNAP-25 to promote SNARE complex assembly in exocytosis.
Chrysin alleviates lipopolysaccharide-induced neuron damage and behavioral deficits in mice through inhibition of Fyn.
METTL3-mediated m(6)A RNA methylation regulates dorsal lingual epithelium homeostasis.
RUNDC3A regulates SNAP25-mediated chemotherapy resistance by binding AKT in gastric neuroendocrine carcinoma (GNEC).
Nuclear speckle specific hnRNP D-like prevents age- and AD-related cognitive decline by modulating RNA splicing.
Neuromodulation Induced by Sitagliptin: A New Strategy for Treating Diabetic Retinopathy.
Chronic hepatitis C virus infection impairs insulin secretion by regulation of p38δ MAPK-dependent exocytosis in pancreatic β-cells.
SNAP25/syntaxin4/VAMP2/Munc18-1 Complexes in Spinal Dorsal Horn Contributed to Inflammatory Pain.
Absence of BBSome function leads to astrocyte reactivity in the brain.
Structural and Functional Analysis of the CAPS SNARE-Binding Domain Required for SNARE Complex Formation and Exocytosis.
miR‑153 promotes neural differentiation in the mouse hippocampal HT‑22 cell line and increases the expression of neuron‑specific enolase.
MicroRNA-210-5p Contributes to Cognitive Impairment in Early Vascular Dementia Rat Model Through Targeting Snap25.
Comparison of the Expression Changes after Botulinum Toxin Type A and Minocycline Administration in Lipopolysaccharide-Stimulated Rat Microglial and Astroglial Cultures.
Lv X, Gao J, Yang J, Zou Y, Chen J, Sun Y, Song J, Liu Y, Wang L, Xia L, Yu S, Wei Z, Chen L, Hou X
Endocrine 2024 Nov;86(2):515-527
Endocrine 2024 Nov;86(2):515-527
Phosphorylation of Doc2 by EphB2 modulates Munc13-mediated SNARE complex assembly and neurotransmitter release.
Zhang H, Lei M, Zhang Y, Li H, He Z, Xie S, Zhu L, Wang S, Liu J, Li Y, Lu Y, Ma C
Science advances 2024 May 17;10(20):eadi7024
Science advances 2024 May 17;10(20):eadi7024
Bavachin ameliorates neuroinflammation and depressive-like behaviors in streptozotocin-induced diabetic mice through the inhibition of PKCδ.
Zhang Z, Sun L, Guo Y, Zhao J, Li J, Pan X, Li Z
Free radical biology & medicine 2024 Mar;213:52-64
Free radical biology & medicine 2024 Mar;213:52-64
L116 Deletion in CSPα Promotes α-Synuclein Aggregation and Neurodegeneration.
Guo T, Xiong J, Feng H, Bu L, Xiao T, Zhou L, He J, Deng M, Liu Y, Zhang Z, Zhang Z
Molecular neurobiology 2024 Jan;61(1):15-27
Molecular neurobiology 2024 Jan;61(1):15-27
Psoralen protects neurons and alleviates neuroinflammation by regulating microglial M1/M2 polarization via inhibition of the Fyn-PKCδ pathway.
Guo Y, Xu S, Pan X, Xin W, Cao W, Ma W, Li L, Shen Q, Li Z
International immunopharmacology 2024 Aug 20;137:112493
International immunopharmacology 2024 Aug 20;137:112493
Intrathecal Injection of Botulinum Toxin Type A has an Analgesic Effect in Male Rats CCI Model by Inhibiting the Activation of Spinal P2X4R.
Zhou WM, Lei ZY, Shi YQ, Gong CY, Kai Z, Wei N, Wang LN, Zhang CJ, Zhang HH
Neurochemical research 2023 Oct;48(10):3099-3112
Neurochemical research 2023 Oct;48(10):3099-3112
Reduced synaptic proteins and SNARE complexes in Down syndrome with Alzheimer's disease and the Dp16 mouse Down syndrome model: Impact of APP gene dose.
Chen XQ, Zuo X, Becker A, Head E, Mobley WC
Alzheimer's & dementia : the journal of the Alzheimer's Association 2023 May;19(5):2095-2116
Alzheimer's & dementia : the journal of the Alzheimer's Association 2023 May;19(5):2095-2116
Comparative study of PRPH2 D2 loop mutants reveals divergent disease mechanism in rods and cones.
Ikelle L, Makia M, Lewis T, Crane R, Kakakhel M, Conley SM, Birtley JR, Arshavsky VY, Al-Ubaidi MR, Naash MI
Cellular and molecular life sciences : CMLS 2023 Jul 19;80(8):214
Cellular and molecular life sciences : CMLS 2023 Jul 19;80(8):214
Rabphilin 3A binds the N-peptide of SNAP-25 to promote SNARE complex assembly in exocytosis.
Li T, Cheng Q, Wang S, Ma C
eLife 2022 Sep 29;11
eLife 2022 Sep 29;11
Chrysin alleviates lipopolysaccharide-induced neuron damage and behavioral deficits in mice through inhibition of Fyn.
Wang Q, Yang Z, Wu X, Zhang X, Geng F, Wang Q, Geng Z, Yu C, Li Z
International immunopharmacology 2022 Oct;111:109118
International immunopharmacology 2022 Oct;111:109118
METTL3-mediated m(6)A RNA methylation regulates dorsal lingual epithelium homeostasis.
Xiong Q, Liu C, Zheng X, Zhou X, Lei K, Zhang X, Wang Q, Lin W, Tong R, Xu R, Yuan Q
International journal of oral science 2022 May 17;14(1):26
International journal of oral science 2022 May 17;14(1):26
RUNDC3A regulates SNAP25-mediated chemotherapy resistance by binding AKT in gastric neuroendocrine carcinoma (GNEC).
Chen P, Wang W, Wong SW, Li J, Wu Q, Zhang SD, Lin Y, Kwok HF
Cell death discovery 2022 Jun 25;8(1):296
Cell death discovery 2022 Jun 25;8(1):296
Nuclear speckle specific hnRNP D-like prevents age- and AD-related cognitive decline by modulating RNA splicing.
Zhang Q, Zhang J, Ye J, Li X, Liu H, Ma X, Wang C, He K, Zhang W, Yuan J, Zhao Y, Xu H, Liu Q
Molecular neurodegeneration 2021 Sep 22;16(1):66
Molecular neurodegeneration 2021 Sep 22;16(1):66
Neuromodulation Induced by Sitagliptin: A New Strategy for Treating Diabetic Retinopathy.
Ramos H, Bogdanov P, Sabater D, Huerta J, Valeri M, Hernández C, Simó R
Biomedicines 2021 Nov 26;9(12)
Biomedicines 2021 Nov 26;9(12)
Chronic hepatitis C virus infection impairs insulin secretion by regulation of p38δ MAPK-dependent exocytosis in pancreatic β-cells.
Chen J, Wang F, Zhou Y, Jiang J, Ksimu S, Zhang X, Li JZ, Niu J, Wang Q
Clinical science (London, England : 1979) 2020 Mar 13;134(5):529-542
Clinical science (London, England : 1979) 2020 Mar 13;134(5):529-542
SNAP25/syntaxin4/VAMP2/Munc18-1 Complexes in Spinal Dorsal Horn Contributed to Inflammatory Pain.
Duan XL, Guo Z, He YT, Li YX, Liu YN, Bai HH, Li HL, Hu XD, Suo ZW
Neuroscience 2020 Mar 1;429:203-212
Neuroscience 2020 Mar 1;429:203-212
Absence of BBSome function leads to astrocyte reactivity in the brain.
Singh M, Garrison JE, Wang K, Sheffield VC
Molecular brain 2019 May 9;12(1):48
Molecular brain 2019 May 9;12(1):48
Structural and Functional Analysis of the CAPS SNARE-Binding Domain Required for SNARE Complex Formation and Exocytosis.
Zhou H, Wei Z, Wang S, Yao D, Zhang R, Ma C
Cell reports 2019 Mar 19;26(12):3347-3359.e6
Cell reports 2019 Mar 19;26(12):3347-3359.e6
miR‑153 promotes neural differentiation in the mouse hippocampal HT‑22 cell line and increases the expression of neuron‑specific enolase.
Xu C, Wang C, Meng Q, Gu Y, Wang Q, Xu W, Han Y, Qin Y, Li J, Jia S, Xu J, Zhou Y
Molecular medicine reports 2019 Aug;20(2):1725-1735
Molecular medicine reports 2019 Aug;20(2):1725-1735
MicroRNA-210-5p Contributes to Cognitive Impairment in Early Vascular Dementia Rat Model Through Targeting Snap25.
Ren Z, Yu J, Wu Z, Si W, Li X, Liu Y, Zhou J, Deng R, Chen D
Frontiers in molecular neuroscience 2018;11:388
Frontiers in molecular neuroscience 2018;11:388
Comparison of the Expression Changes after Botulinum Toxin Type A and Minocycline Administration in Lipopolysaccharide-Stimulated Rat Microglial and Astroglial Cultures.
Piotrowska A, Popiolek-Barczyk K, Pavone F, Mika J
Frontiers in cellular and infection microbiology 2017;7:141
Frontiers in cellular and infection microbiology 2017;7:141
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SNAP25 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SNAP25. This antibody recognizes human,mouse,rat antigen. The SNAP25 antibody has been validated for the following applications: ELISA, WB analysis.
