orb154251

antibody from Biorbyt
Targeting: TEC PSCTK4
Provider product page for orb154251
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
orb154251 - Provider product page
Provider
Biorbyt
Product name
Tec antibody
Antibody type
Polyclonal
Description
Rabbit polyclonal antibody to Tec. Tec is a member of the Tec family of non-receptor protein-tyrosine kinase (PTK) which also includes Btk, emtk/itk/Tsk, Rlk/Txx and Bmx. Tec is composed of a pleckstrin domain (PH), an SH3 and SH2 domain, a catalytic kinase domain and a Tec homology domain (TH). Tecs TH domain interacts with the SH3 domain of Grb2, Src family PTKs ( Fyn, Lyn, and Hck), Vav, and c-Kit. Tec is mostly expressed in hematopoietic cells. Tecs SH3 domain interacts with DC28 and has been shown to phosphorylate p62 dok, CD28 substrate. Tec can phosphorylate Jak kinase in hematopoietic cellsand can also be phosphorylated by Src member Lyn on multiple tyrosine residues.
Reactivity
Human, Mouse, Rat
Conjugate
Unconjugated
Isotype
IgG
Vial size
50 ul
Storage
Store at -20°C. Avoid freeze / thaw cycles.
TEC protein structure - orb154251 shown in red.