Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- MAB8321 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB8321, RRID:AB_10616783
- Product name
- TYK2 monoclonal antibody, clone 8G8E9,8G9H5
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised against partial recombinant TYK2.
- Isotype
- IgG
- Antibody clone number
- 8G8E9,8G9H5
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Tyk2 negatively regulates adaptive Th1 immunity by mediating IL-10 signaling and promoting IFN-gamma-dependent IL-10 reactivation.
TYK2 is a key regulator of the surveillance of B lymphoid tumors.
Enhanced Th2 cell-mediated allergic inflammation in Tyk2-deficient mice.
Shaw MH, Freeman GJ, Scott MF, Fox BA, Bzik DJ, Belkaid Y, Yap GS
Journal of immunology (Baltimore, Md. : 1950) 2006 Jun 15;176(12):7263-71
Journal of immunology (Baltimore, Md. : 1950) 2006 Jun 15;176(12):7263-71
TYK2 is a key regulator of the surveillance of B lymphoid tumors.
Stoiber D, Kovacic B, Schuster C, Schellack C, Karaghiosoff M, Kreibich R, Weisz E, Artwohl M, Kleine OC, Muller M, Baumgartner-Parzer S, Ghysdael J, Freissmuth M, Sexl V
The Journal of clinical investigation 2004 Dec;114(11):1650-8
The Journal of clinical investigation 2004 Dec;114(11):1650-8
Enhanced Th2 cell-mediated allergic inflammation in Tyk2-deficient mice.
Seto Y, Nakajima H, Suto A, Shimoda K, Saito Y, Nakayama KI, Iwamoto I
Journal of immunology (Baltimore, Md. : 1950) 2003 Jan 15;170(2):1077-83
Journal of immunology (Baltimore, Md. : 1950) 2003 Jan 15;170(2):1077-83
No comments: Submit comment
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analyssi using TYK2 monoclonal antibody, clone 8G8E9, 8G9H5 (Cat # MAB8321) against trucated TYK2 recombinant protein (Lane 1) and Jurkat cell lysate (Lane 2).