ABIN362700

antibody from antibodies-online

Targeting: TYK2 JTK1

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN362700

Provider

antibodies-online

Product name

anti-Tyrosine Kinase 2 (TYK2) (AA 1052-1056) antibody

Antibody type

Polyclonal

Antigen

Peptide sequence around AA 1052-1056 (H-E-Y-Y-R) derived from Human TYK2. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.

Reactivity

Human, Mouse

Host

Rabbit

Epitope

AA 1052-1056

Isotype

IgG

Vial size

100 μL

Concentration

1 mg/mL

Storage

Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

References

Submitted references

Phosphotyrosine proteomic study of interferon alpha signaling pathway using a combination of immunoprecipitation and immobilized metal affinity chromatography.

Zheng H, Hu P, Quinn DF, Wang YK
Molecular & cellular proteomics : MCP 2005 Jun;4(6):721-30

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Interferon-alpha-dependent activation of Tyk2 requires phosphorylation of positive regulatory tyrosines by another kinase.

Gauzzi MC, Velazquez L, McKendry R, Mogensen KE, Fellous M, Pellegrini S
The Journal of biological chemistry 1996 Aug 23;271(34):20494-500