ABIN969448

antibody from antibodies-online

Targeting: TYK2 JTK1

Western blot (Supportive data in Antibodypedia)

ELISA (Recommended by provider)

Antibody Data

Product number

ABIN969448

Provider

antibodies-online

Product name

anti-Tyrosine Kinase 2 (TYK2) antibody

Antibody type

Monoclonal

Description

Ascites

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

8G8B3

Vial size

100 μL

Storage

4°C, -20°C for long term storage

References

Submitted references

Tyk2 negatively regulates adaptive Th1 immunity by mediating IL-10 signaling and promoting IFN-gamma-dependent IL-10 reactivation.

Shaw MH, Freeman GJ, Scott MF, Fox BA, Bzik DJ, Belkaid Y, Yap GS
Journal of immunology (Baltimore, Md. : 1950) 2006 Jun 15;176(12):7263-71

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Enhanced Th2 cell-mediated allergic inflammation in Tyk2-deficient mice.

Seto Y, Nakajima H, Suto A, Shimoda K, Saito Y, Nakayama KI, Iwamoto I
Journal of immunology (Baltimore, Md. : 1950) 2003 Jan 15;170(2):1077-83

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB