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Western blot
ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
- References [7]
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- Validations
- Western blot [1]
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- Product number
- AP08705PU-N - Provider product page
- Provider
- Acris Antibodies GmbH
- Proper citation
- Acris Antibodies GmbH Cat#AP08705PU-N, RRID:AB_1975627
- Product name
- anti NMDAR2B (C-term)
- Antibody type
- Polyclonal
- Antigen
- Fusion protein from the C-terminus of the NR2B subunit of rat NMDA Receptor.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 10 µg
Submitted references Moderate prenatal alcohol exposure reduces plasticity and alters NMDA receptor subunit composition in the dentate gyrus.
Alcohol inhibition of the NMDA receptor function, long-term potentiation, and fear learning requires striatal-enriched protein tyrosine phosphatase.
Abeta-mediated NMDA receptor endocytosis in Alzheimer's disease involves ubiquitination of the tyrosine phosphatase STEP61.
Extrasynaptic NMDA receptors couple preferentially to excitotoxicity via calpain-mediated cleavage of STEP.
Long term synaptic depression that is associated with GluR1 dephosphorylation but not alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor internalization.
Neurite degeneration induced by heme deficiency mediated via inhibition of NMDA receptor-dependent extracellular signal-regulated kinase 1/2 activation.
Modulation of NR2B-regulated contextual fear in the hippocampus by the tissue plasminogen activator system.
Brady ML, Diaz MR, Iuso A, Everett JC, Valenzuela CF, Caldwell KK
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Jan 16;33(3):1062-7
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Jan 16;33(3):1062-7
Alcohol inhibition of the NMDA receptor function, long-term potentiation, and fear learning requires striatal-enriched protein tyrosine phosphatase.
Hicklin TR, Wu PH, Radcliffe RA, Freund RK, Goebel-Goody SM, Correa PR, Proctor WR, Lombroso PJ, Browning MD
Proceedings of the National Academy of Sciences of the United States of America 2011 Apr 19;108(16):6650-5
Proceedings of the National Academy of Sciences of the United States of America 2011 Apr 19;108(16):6650-5
Abeta-mediated NMDA receptor endocytosis in Alzheimer's disease involves ubiquitination of the tyrosine phosphatase STEP61.
Kurup P, Zhang Y, Xu J, Venkitaramani DV, Haroutunian V, Greengard P, Nairn AC, Lombroso PJ
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 Apr 28;30(17):5948-57
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 Apr 28;30(17):5948-57
Extrasynaptic NMDA receptors couple preferentially to excitotoxicity via calpain-mediated cleavage of STEP.
Xu J, Kurup P, Zhang Y, Goebel-Goody SM, Wu PH, Hawasli AH, Baum ML, Bibb JA, Lombroso PJ
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 Jul 22;29(29):9330-43
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 Jul 22;29(29):9330-43
Long term synaptic depression that is associated with GluR1 dephosphorylation but not alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor internalization.
Davies KD, Goebel-Goody SM, Coultrap SJ, Browning MD
The Journal of biological chemistry 2008 Nov 28;283(48):33138-46
The Journal of biological chemistry 2008 Nov 28;283(48):33138-46
Neurite degeneration induced by heme deficiency mediated via inhibition of NMDA receptor-dependent extracellular signal-regulated kinase 1/2 activation.
Chernova T, Steinert JR, Guerin CJ, Nicotera P, Forsythe ID, Smith AG
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007 Aug 8;27(32):8475-85
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007 Aug 8;27(32):8475-85
Modulation of NR2B-regulated contextual fear in the hippocampus by the tissue plasminogen activator system.
Norris EH, Strickland S
Proceedings of the National Academy of Sciences of the United States of America 2007 Aug 14;104(33):13473-8
Proceedings of the National Academy of Sciences of the United States of America 2007 Aug 14;104(33):13473-8
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Supportive validation
- Submitted by
- Acris Antibodies GmbH (provider)
- Main image
- Experimental details
- Western blot of 10 µg of rat hippocampal lysate showing specific immunolabeling of the ~180k NR2B subunit of the NMDA Receptor.
