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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [16]
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- Product number
- ABIN372682 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- Fusion protein from the C-terminus of the NR2B subunit of rat NMDA Receptor.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 10 µg
- Storage
- Store the antibody undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Submitted references Moderate prenatal alcohol exposure reduces plasticity and alters NMDA receptor subunit composition in the dentate gyrus.
Alcohol inhibition of the NMDA receptor function, long-term potentiation, and fear learning requires striatal-enriched protein tyrosine phosphatase.
Abeta-mediated NMDA receptor endocytosis in Alzheimer's disease involves ubiquitination of the tyrosine phosphatase STEP61.
Extrasynaptic NMDA receptors couple preferentially to excitotoxicity via calpain-mediated cleavage of STEP.
Spherical aberration correction suitable for a wavefront controller.
Long term synaptic depression that is associated with GluR1 dephosphorylation but not alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor internalization.
Neurite degeneration induced by heme deficiency mediated via inhibition of NMDA receptor-dependent extracellular signal-regulated kinase 1/2 activation.
Trafficking of NMDA receptors.
Tyrosine dephosphorylation and ethanol inhibition of N-Methyl-D-aspartate receptor function.
NMDA-receptor trafficking and targeting: implications for synaptic transmission and plasticity.
A hippocampal NR2B deficit can mimic age-related changes in long-term potentiation and spatial learning in the Fischer 344 rat.
LTP leads to rapid surface expression of NMDA but not AMPA receptors in adult rat CA1.
Aging and surface expression of hippocampal NMDA receptors.
G-protein-coupled receptors act via protein kinase C and Src to regulate NMDA receptors.
Regional and subunit specific changes in NMDA receptor mRNA and immunoreactivity in mouse brain following chronic ethanol ingestion.
Ethanol inhibits NMDA-activated ion current in hippocampal neurons.
Brady ML, Diaz MR, Iuso A, Everett JC, Valenzuela CF, Caldwell KK
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Jan 16;33(3):1062-7
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Jan 16;33(3):1062-7
Alcohol inhibition of the NMDA receptor function, long-term potentiation, and fear learning requires striatal-enriched protein tyrosine phosphatase.
Hicklin TR, Wu PH, Radcliffe RA, Freund RK, Goebel-Goody SM, Correa PR, Proctor WR, Lombroso PJ, Browning MD
Proceedings of the National Academy of Sciences of the United States of America 2011 Apr 19;108(16):6650-5
Proceedings of the National Academy of Sciences of the United States of America 2011 Apr 19;108(16):6650-5
Abeta-mediated NMDA receptor endocytosis in Alzheimer's disease involves ubiquitination of the tyrosine phosphatase STEP61.
Kurup P, Zhang Y, Xu J, Venkitaramani DV, Haroutunian V, Greengard P, Nairn AC, Lombroso PJ
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 Apr 28;30(17):5948-57
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 Apr 28;30(17):5948-57
Extrasynaptic NMDA receptors couple preferentially to excitotoxicity via calpain-mediated cleavage of STEP.
Xu J, Kurup P, Zhang Y, Goebel-Goody SM, Wu PH, Hawasli AH, Baum ML, Bibb JA, Lombroso PJ
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 Jul 22;29(29):9330-43
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 Jul 22;29(29):9330-43
Spherical aberration correction suitable for a wavefront controller.
Itoh H, Matsumoto N, Inoue T
Optics express 2009 Aug 3;17(16):14367-73
Optics express 2009 Aug 3;17(16):14367-73
Long term synaptic depression that is associated with GluR1 dephosphorylation but not alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor internalization.
Davies KD, Goebel-Goody SM, Coultrap SJ, Browning MD
The Journal of biological chemistry 2008 Nov 28;283(48):33138-46
The Journal of biological chemistry 2008 Nov 28;283(48):33138-46
Neurite degeneration induced by heme deficiency mediated via inhibition of NMDA receptor-dependent extracellular signal-regulated kinase 1/2 activation.
Chernova T, Steinert JR, Guerin CJ, Nicotera P, Forsythe ID, Smith AG
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007 Aug 8;27(32):8475-85
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007 Aug 8;27(32):8475-85
Trafficking of NMDA receptors.
Wenthold RJ, Prybylowski K, Standley S, Sans N, Petralia RS
Annual review of pharmacology and toxicology 2003;43:335-58
Annual review of pharmacology and toxicology 2003;43:335-58
Tyrosine dephosphorylation and ethanol inhibition of N-Methyl-D-aspartate receptor function.
Alvestad RM, Grosshans DR, Coultrap SJ, Nakazawa T, Yamamoto T, Browning MD
The Journal of biological chemistry 2003 Mar 28;278(13):11020-5
The Journal of biological chemistry 2003 Mar 28;278(13):11020-5
NMDA-receptor trafficking and targeting: implications for synaptic transmission and plasticity.
Carroll RC, Zukin RS
Trends in neurosciences 2002 Nov;25(11):571-7
Trends in neurosciences 2002 Nov;25(11):571-7
A hippocampal NR2B deficit can mimic age-related changes in long-term potentiation and spatial learning in the Fischer 344 rat.
Clayton DA, Mesches MH, Alvarez E, Bickford PC, Browning MD
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002 May 1;22(9):3628-37
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002 May 1;22(9):3628-37
LTP leads to rapid surface expression of NMDA but not AMPA receptors in adult rat CA1.
Grosshans DR, Clayton DA, Coultrap SJ, Browning MD
Nature neuroscience 2002 Jan;5(1):27-33
Nature neuroscience 2002 Jan;5(1):27-33
Aging and surface expression of hippocampal NMDA receptors.
Clayton DA, Grosshans DR, Browning MD
The Journal of biological chemistry 2002 Apr 26;277(17):14367-9
The Journal of biological chemistry 2002 Apr 26;277(17):14367-9
G-protein-coupled receptors act via protein kinase C and Src to regulate NMDA receptors.
Lu WY, Xiong ZG, Lei S, Orser BA, Dudek E, Browning MD, MacDonald JF
Nature neuroscience 1999 Apr;2(4):331-8
Nature neuroscience 1999 Apr;2(4):331-8
Regional and subunit specific changes in NMDA receptor mRNA and immunoreactivity in mouse brain following chronic ethanol ingestion.
Snell LD, Nunley KR, Lickteig RL, Browning MD, Tabakoff B, Hoffman PL
Brain research. Molecular brain research 1996 Aug;40(1):71-8
Brain research. Molecular brain research 1996 Aug;40(1):71-8
Ethanol inhibits NMDA-activated ion current in hippocampal neurons.
Lovinger DM, White G, Weight FF
Science (New York, N.Y.) 1989 Mar 31;243(4899):1721-4
Science (New York, N.Y.) 1989 Mar 31;243(4899):1721-4
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