Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations [0]
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- Product number
- ABIN362259 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Epidermal Growth Factor Receptor (EGFR) (pTyr1172) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around phosphorylation site of pTyr1172 (P-D-Y (p) -Q-Q) derived from Human EGFR. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- pTyr1172
- Isotype
- IgG
- Vial size
- 50 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect.
PKM2 phosphorylates histone H3 and promotes gene transcription and tumorigenesis.
The HER-2/neu receptor tyrosine kinase gene encodes a secreted autoinhibitor.
Tyrosine phosphorylation of selected secretory carrier membrane proteins, SCAMP1 and SCAMP3, and association with the EGF receptor.
Role of SH-PTP2, a protein-tyrosine phosphatase with Src homology 2 domains, in insulin-stimulated Ras activation.
Tyrosine phosphorylation of a 120-kilodalton pp60src substrate upon epidermal growth factor and platelet-derived growth factor receptor stimulation and in polyomavirus middle-T-antigen-transformed cells.
Yang W, Zheng Y, Xia Y, Ji H, Chen X, Guo F, Lyssiotis CA, Aldape K, Cantley LC, Lu Z
Nature cell biology 2012 Dec;14(12):1295-304
Nature cell biology 2012 Dec;14(12):1295-304
PKM2 phosphorylates histone H3 and promotes gene transcription and tumorigenesis.
Yang W, Xia Y, Hawke D, Li X, Liang J, Xing D, Aldape K, Hunter T, Alfred Yung WK, Lu Z
Cell 2012 Aug 17;150(4):685-96
Cell 2012 Aug 17;150(4):685-96
The HER-2/neu receptor tyrosine kinase gene encodes a secreted autoinhibitor.
Doherty JK, Bond C, Jardim A, Adelman JP, Clinton GM
Proceedings of the National Academy of Sciences of the United States of America 1999 Sep 14;96(19):10869-74
Proceedings of the National Academy of Sciences of the United States of America 1999 Sep 14;96(19):10869-74
Tyrosine phosphorylation of selected secretory carrier membrane proteins, SCAMP1 and SCAMP3, and association with the EGF receptor.
Wu TT, Castle JD
Molecular biology of the cell 1998 Jul;9(7):1661-74
Molecular biology of the cell 1998 Jul;9(7):1661-74
Role of SH-PTP2, a protein-tyrosine phosphatase with Src homology 2 domains, in insulin-stimulated Ras activation.
Noguchi T, Matozaki T, Horita K, Fujioka Y, Kasuga M
Molecular and cellular biology 1994 Oct;14(10):6674-82
Molecular and cellular biology 1994 Oct;14(10):6674-82
Tyrosine phosphorylation of a 120-kilodalton pp60src substrate upon epidermal growth factor and platelet-derived growth factor receptor stimulation and in polyomavirus middle-T-antigen-transformed cells.
Kanner SB, Reynolds AB, Parsons JT
Molecular and cellular biology 1991 Feb;11(2):713-20
Molecular and cellular biology 1991 Feb;11(2):713-20
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