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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [17]
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- Validations
- Immunohistochemistry [1]
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- Product number
- HPA018530 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA018530, RRID:AB_1848044
- Product name
- Anti-EGFR
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human EGFR, Gene description: epidermal growth factor receptor, Alternative Gene Names: ERBB, ERBB1, Validated applications: WB, IHC, ICC, Uniprot ID: P00533, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Oncogenic Roles of Laminin Subunit Gamma‐2 in Intrahepatic Cholangiocarcinoma via Promoting EGFR Translation
Cetuximab-Toxin Conjugate and NPe6 with Light Enhanced Cytotoxic Effects in Head and Neck Squamous Cell Carcinoma In Vitro.
ErbB signaling is a potential therapeutic target for vascular lesions with fibrous component
Association of Irisin/FNDC5 with ERRα and PGC-1α Expression in NSCLC
Expression of VEGF, EGF, and Their Receptors in Squamous Esophageal Mucosa, with Correlations to Histological Findings and Endoscopic Minimal Changes, in Patients with Different GERD Phenotypes
Triple-Negative Breast Cancer: Assessing the Role of Immunohistochemical Biomarkers on Neoadjuvant Treatment
Minocycline prevents and repairs the skin disorder associated with afatinib, one of the epidermal growth factor receptor-tyrosine kinase inhibitors for non-small cell lung cancer
The CHORD protein CHP-1 regulates EGF receptor trafficking and signaling in C. elegans and in human cells.
Modulating EGFR-MTORC1-autophagy as a potential therapy for persistent fetal vasculature (PFV) disease
Prognostic Impact of Melatonin Receptors MT1 and MT2 in Non-Small Cell Lung Cancer (NSCLC)
Altered transcriptional regulatory proteins in glioblastoma and YBX1 as a potential regulator of tumor invasion.
CRISPR/Cas9 Genome Editing of Epidermal Growth Factor Receptor Sufficiently Abolished Oncogenicity in Anaplastic Thyroid Cancer
The Role of BCA2 in the Endocytic Trafficking of EGFR and Significance as a Prognostic Biomarker in Cancer
Resetting cancer stem cell regulatory nodes upon MYC inhibition
Microsomal membrane proteome of low grade diffuse astrocytomas: Differentially expressed proteins and candidate surveillance biomarkers.
Sentinel Lymph Node Biopsy Revisited: Ultrasound-Guided Photoacoustic Detection of Micrometastases Using Molecularly Targeted Plasmonic Nanosensors
Proteomic screen reveals Fbw7 as a modulator of the NF-κB pathway
Zhang J, Ji F, Tan Y, Zhao L, Zhao Y, Liu J, Shao L, Shi J, Ye M, He X, Jin J, Zhao B, Huang J, Roessler S, Zheng X, Ji J
Advanced Science 2024;11(21)
Advanced Science 2024;11(21)
Cetuximab-Toxin Conjugate and NPe6 with Light Enhanced Cytotoxic Effects in Head and Neck Squamous Cell Carcinoma In Vitro.
Komatsu N, Kosai A, Kuroda M, Hamakubo T, Abe T
Biomedicines 2024 Apr 29;12(5)
Biomedicines 2024 Apr 29;12(5)
ErbB signaling is a potential therapeutic target for vascular lesions with fibrous component
Ilmonen H, Jauhiainen S, Vuola P, Rasinkangas H, Pulkkinen H, Keränen S, Kiema M, Liikkanen J, Laham-Karam N, Laidinen S, Beter M, Aavik E, Lappalainen K, Lohi J, Aronniemi J, Örd T, Kaikkonen M, Salminen P, Tukiainen E, Ylä-Herttuala S, Laakkonen J
eLife 2023;12
eLife 2023;12
Association of Irisin/FNDC5 with ERRα and PGC-1α Expression in NSCLC
Nowińska K, Jabłońska K, Ciesielska U, Piotrowska A, Haczkiewicz-Leśniak K, Pawełczyk K, Podhorska-Okołów M, Dzięgiel P
International Journal of Molecular Sciences 2022;23(22):14204
International Journal of Molecular Sciences 2022;23(22):14204
Expression of VEGF, EGF, and Their Receptors in Squamous Esophageal Mucosa, with Correlations to Histological Findings and Endoscopic Minimal Changes, in Patients with Different GERD Phenotypes
Wasielica-Berger J, Rogalski P, Świdnicka-Siergiejko A, Pryczynicz A, Kiśluk J, Daniluk J, Antonowicz S, Maślach D, Krzyżak M, Dąbrowski A
International Journal of Environmental Research and Public Health 2022;19(9):5298
International Journal of Environmental Research and Public Health 2022;19(9):5298
Triple-Negative Breast Cancer: Assessing the Role of Immunohistochemical Biomarkers on Neoadjuvant Treatment
da Silva J, Rodrigues F, de Mesquita G, Fernandes P, Thuler L, de Melo A
Breast Cancer: Targets and Therapy 2021;Volume 13
Breast Cancer: Targets and Therapy 2021;Volume 13
Minocycline prevents and repairs the skin disorder associated with afatinib, one of the epidermal growth factor receptor-tyrosine kinase inhibitors for non-small cell lung cancer
Sano K, Nakadate K, Hanada K
BMC Cancer 2020;20(1)
BMC Cancer 2020;20(1)
The CHORD protein CHP-1 regulates EGF receptor trafficking and signaling in C. elegans and in human cells.
Haag A, Walser M, Henggeler A, Hajnal A
eLife 2020 Feb 13;9
eLife 2020 Feb 13;9
Modulating EGFR-MTORC1-autophagy as a potential therapy for persistent fetal vasculature (PFV) disease
Yazdankhah M, Shang P, Ghosh S, Bhutto I, Stepicheva N, Grebe R, Hose S, Weiss J, Luo T, Mishra S, Riazuddin S, Ghosh A, Handa J, Lutty G, Zigler J, Sinha D
Autophagy 2019;16(6):1130-1142
Autophagy 2019;16(6):1130-1142
Prognostic Impact of Melatonin Receptors MT1 and MT2 in Non-Small Cell Lung Cancer (NSCLC)
Jablonska K, Nowinska K, Piotrowska A, Partynska A, Katnik E, Pawelczyk K, Kmiecik A, Glatzel-Plucinska N, Podhorska-Okolow M, Dziegiel P
Cancers 2019;11(7):1001
Cancers 2019;11(7):1001
Altered transcriptional regulatory proteins in glioblastoma and YBX1 as a potential regulator of tumor invasion.
Gupta MK, Polisetty RV, Sharma R, Ganesh RA, Gowda H, Purohit AK, Ankathi P, Prasad K, Mariswamappa K, Lakshmikantha A, Uppin MS, Sundaram C, Gautam P, Sirdeshmukh R
Scientific reports 2019 Jul 29;9(1):10986
Scientific reports 2019 Jul 29;9(1):10986
CRISPR/Cas9 Genome Editing of Epidermal Growth Factor Receptor Sufficiently Abolished Oncogenicity in Anaplastic Thyroid Cancer
Huang L, Tam K, Liu W, Lin C, Hsu K, Hsieh W, Chi W, Lee A, Yang J, Lin C, Lee C
Disease Markers 2018;2018
Disease Markers 2018;2018
The Role of BCA2 in the Endocytic Trafficking of EGFR and Significance as a Prognostic Biomarker in Cancer
Wymant J, Hiscox S, Westwell A, Urbé S, Clague M, Jones A
Journal of Cancer 2016;7(15):2388-2407
Journal of Cancer 2016;7(15):2388-2407
Resetting cancer stem cell regulatory nodes upon MYC inhibition
Galardi S, Savino M, Scagnoli F, Pellegatta S, Pisati F, Zambelli F, Illi B, Annibali D, Beji S, Orecchini E, Alberelli M, Apicella C, Fontanella R, Michienzi A, Finocchiaro G, Farace M, Pavesi G, Ciafrè S, Nasi S
EMBO reports 2016;17(12):1872-1889
EMBO reports 2016;17(12):1872-1889
Microsomal membrane proteome of low grade diffuse astrocytomas: Differentially expressed proteins and candidate surveillance biomarkers.
Polisetty RV, Gautam P, Gupta MK, Sharma R, Gowda H, Renu D, Shivakumar BM, Lakshmikantha A, Mariswamappa K, Ankathi P, Purohit AK, Uppin MS, Sundaram C, Sirdeshmukh R
Scientific reports 2016 Jun 1;6:26882
Scientific reports 2016 Jun 1;6:26882
Sentinel Lymph Node Biopsy Revisited: Ultrasound-Guided Photoacoustic Detection of Micrometastases Using Molecularly Targeted Plasmonic Nanosensors
Luke G, Myers J, Emelianov S, Sokolov K
Cancer Research 2014;74(19):5397-5408
Cancer Research 2014;74(19):5397-5408
Proteomic screen reveals Fbw7 as a modulator of the NF-κB pathway
Arabi A, Ullah K, Branca R, Johansson J, Bandarra D, Haneklaus M, Fu J, Ariës I, Nilsson P, Den Boer M, Pokrovskaja K, Grandér D, Xiao G, Rocha S, Lehtiö J, Sangfelt O
Nature Communications 2012;3(1)
Nature Communications 2012;3(1)
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human placenta and tonsil tissues using HPA018530 antibody. Corresponding EGFR RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
