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- Antibody Data
- Antigen structure
- References [6]
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- Product number
- ABIN967602 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Epidermal Growth Factor Receptor (EGFR) (pTyr845) antibody
- Antibody type
- Monoclonal
- Antigen
- Phosphorylated Human EGF Receptor Peptide
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 12A3
- Vial size
- 0.1 mg
- Concentration
- 0.5 mg/ml
- Storage
- Store undiluted at 4°C.
Submitted references Phosphorylation of Y845 on the epidermal growth factor receptor mediates binding to the mitochondrial protein cytochrome c oxidase subunit II.
Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer.
Integrin-induced epidermal growth factor (EGF) receptor activation requires c-Src and p130Cas and leads to phosphorylation of specific EGF receptor tyrosines.
Src-dependent phosphorylation of the epidermal growth factor receptor on tyrosine 845 is required for zinc-induced Ras activation.
The ErbB signaling network: receptor heterodimerization in development and cancer.
c-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function.
Boerner JL, Demory ML, Silva C, Parsons SJ
Molecular and cellular biology 2004 Aug;24(16):7059-71
Molecular and cellular biology 2004 Aug;24(16):7059-71
Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer.
Mendelsohn J, Baselga J
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003 Jul 15;21(14):2787-99
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003 Jul 15;21(14):2787-99
Integrin-induced epidermal growth factor (EGF) receptor activation requires c-Src and p130Cas and leads to phosphorylation of specific EGF receptor tyrosines.
Moro L, Dolce L, Cabodi S, Bergatto E, Boeri Erba E, Smeriglio M, Turco E, Retta SF, Giuffrida MG, Venturino M, Godovac-Zimmermann J, Conti A, Schaefer E, Beguinot L, Tacchetti C, Gaggini P, Silengo L, Tarone G, Defilippi P
The Journal of biological chemistry 2002 Mar 15;277(11):9405-14
The Journal of biological chemistry 2002 Mar 15;277(11):9405-14
Src-dependent phosphorylation of the epidermal growth factor receptor on tyrosine 845 is required for zinc-induced Ras activation.
Wu W, Graves LM, Gill GN, Parsons SJ, Samet JM
The Journal of biological chemistry 2002 Jul 5;277(27):24252-7
The Journal of biological chemistry 2002 Jul 5;277(27):24252-7
The ErbB signaling network: receptor heterodimerization in development and cancer.
Olayioye MA, Neve RM, Lane HA, Hynes NE
The EMBO journal 2000 Jul 3;19(13):3159-67
The EMBO journal 2000 Jul 3;19(13):3159-67
c-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function.
Biscardi JS, Maa MC, Tice DA, Cox ME, Leu TH, Parsons SJ
The Journal of biological chemistry 1999 Mar 19;274(12):8335-43
The Journal of biological chemistry 1999 Mar 19;274(12):8335-43
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