NBP1-89909

antibody from Novus Biologicals

Targeting: LAMTOR1 C11orf59, FLJ20625, p18, p27RF-Rho, Pdro, Ragulator1

Western blot (Supportive data in Antibodypedia)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

NBP1-89909

Provider

Novus Biologicals

Proper citation

Novus Cat#NBP1-89909, RRID:AB_11015229

Product name

Rabbit Polyclonal LAMTOR1 Antibody

Antibody type

Polyclonal

Description

Immunogen affinity purified. Specificity of human c11orf59/LAMTOR1 antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.

Reactivity

Human

Host

Rabbit

Isotype

IgG

Vial size

0.1 ml

Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

References

Submitted references

LAMTOR2/LAMTOR1 complex is required for TAX1BP1-mediated xenophagy.

Lin CY, Nozawa T, Minowa-Nozawa A, Toh H, Aikawa C, Nakagawa I
Cellular microbiology 2019 Apr;21(4):e12981

---

mTOR activates the VPS34-UVRAG complex to regulate autolysosomal tubulation and cell survival.

Munson MJ, Allen GF, Toth R, Campbell DG, Lucocq JM, Ganley IG
The EMBO journal 2015 Sep 2;34(17):2272-90

---

MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB.

Martina JA, Chen Y, Gucek M, Puertollano R
Autophagy 2012 Jun;8(6):903-14

---

The late endosomal adaptor p14 is a macrophage host-defense factor against Salmonella infection.

Taub N, Nairz M, Hilber D, Hess MW, Weiss G, Huber LA
Journal of cell science 2012 Jun 1;125(Pt 11):2698-708

---

Proteomic analysis of endosomes from genetically modified p14/MP1 mouse embryonic fibroblasts.

Stasyk T, Holzmann J, Stumberger S, Ebner HL, Hess MW, Bonn GK, Mechtler K, Huber LA
Proteomics 2010 Nov;10(22):4117-27

Western blot

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Western Blot: LAMTOR1 Antibody [NBP1-89909] - Analysis in human cell line A-549.

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Western Blot: LAMTOR1 Antibody [NBP1-89909] - Analysis in MCF-7 cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-LAMTOR1 antibody. Remaining relative intensity is presented. Loading control: Anti-GAPDH.

Immunohistochemistry

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Immunohistochemistry-Paraffin: c11orf59/LAMTOR1 Antibody [NBP1-89909] - Staining of human rectum shows strong cytoplasmic positivity, with a granular pattern, in glandular cells.

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Immunohistochemistry-Paraffin: LAMTOR1 Antibody [NBP1-89909] - Staining of human duodenum shows strong granular cytoplasmic positivity in glandular cells.

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Immunohistochemistry-Paraffin: LAMTOR1 Antibody [NBP1-89909] - Staining of human skin shows strong positivity in cytoplasm granular in squamous epithelial cells.

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Immunohistochemistry-Paraffin: LAMTOR1 Antibody [NBP1-89909] - Staining of human pancreas shows strong granular cytoplasmic positivity in exocrine glandular cells.

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Immunohistochemistry-Paraffin: LAMTOR1 Antibody [NBP1-89909] - Staining of human tonsil shows strong positivity in cytoplasm granular in non-germinal center cells.

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Immunohistochemistry-Paraffin: LAMTOR1 Antibody [NBP1-89909] - Staining of human prostate shows strong granular cytoplasmic positivity in glandular cells.