Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 21082-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21082-1-AP, RRID:AB_10695770
- Product name
- CCDC50 antibody
- Antibody type
- Polyclonal
- Description
- CCDC50 antibody (Cat. #21082-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references TAX1BP1-dependent autophagic degradation of STING1 impairs anti-tumor immunity.
CCDC50 mediates the clearance of protein aggregates to prevent cellular proteotoxicity.
CCDC50 promotes tumor growth through regulation of lysosome homeostasis.
CCDC50 suppresses NLRP3 inflammasome activity by mediating autophagic degradation of NLRP3.
Zhang R, Yu C, Zeh HJ, Kroemer G, Klionsky DJ, Tang D, Kang R
Autophagy 2025 Aug;21(8):1802-1823
Autophagy 2025 Aug;21(8):1802-1823
CCDC50 mediates the clearance of protein aggregates to prevent cellular proteotoxicity.
Ye Y, Jia P, Miao J, Wang Y, Li Z, Lin Y, He M, Liu S, Zheng BR, Wu J, Pan J, Li CM, Hou P, Guo D
Autophagy 2024 Nov;20(11):2529-2539
Autophagy 2024 Nov;20(11):2529-2539
CCDC50 promotes tumor growth through regulation of lysosome homeostasis.
Jia P, Tian T, Li Z, Wang Y, Lin Y, Zeng W, Ye Y, He M, Ni X, Pan J, Dong X, Huang J, Li CM, Guo D, Hou P
EMBO reports 2023 Oct 9;24(10):e56948
EMBO reports 2023 Oct 9;24(10):e56948
CCDC50 suppresses NLRP3 inflammasome activity by mediating autophagic degradation of NLRP3.
Lin Y, Li Z, Wang Y, Tian T, Jia P, Ye Y, He M, Yang Z, Li C, Guo D, Hou P
EMBO reports 2022 May 4;23(5):e54453
EMBO reports 2022 May 4;23(5):e54453
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- K-562 cells were subjected to SDS PAGE followed by western blot with 21082-1-AP(CCDC50 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 21082-1-AP(CCDC50 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CCDC50 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human CCDC50. This antibody recognizes human, mouse, rat antigen. The CCDC50 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
