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GDF2
Growth differentiation factor 2BMP-9, BMP9
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates cartilage and bone development, angiogenesis and differentiation of cholinergic central nervous system neurons. Mutations in this gene are associated with hereditary hemorrhagic telangiectasia. [provided by RefSeq, Jul 2016]
Top validated antibodies |
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| R&D Systems |  MAB3209-100 |
9 references | Monoclonal |
WB
EL
BN
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| antibodies-online | ABIN2839135 |
5 references | Polyclonal |
WB
IHC
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| Abnova Corporation | PAB3885 |
3 references | Polyclonal |
WB
IHC
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| GeneTex | GTX108417 |
1 references | Polyclonal |
WB
ICC
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| Invitrogen Antibodies | PA5-11931 |
1 references | Polyclonal |
WB
IHC
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