Tissue expression
Cell line expression
Protein structure
GDF2
Growth differentiation factor 2BMP-9, BMP9
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates cartilage and bone development, angiogenesis and differentiation of cholinergic central nervous system neurons. Mutations in this gene are associated with hereditary hemorrhagic telangiectasia. [provided by RefSeq, Jul 2016]
Top validated antibodies |
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LSBio | ![]() |
Polyclonal |
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R&D Systems | ![]() |
9 references | Monoclonal |
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antibodies-online | ![]() |
5 references | Polyclonal |
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Abnova Corporation | ![]() |
3 references | Polyclonal |
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Antibodies.com | ![]() |
Polyclonal |
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